中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [10]
深圳先进技术研究院 [2]
采集方式
OAI收割 [12]
内容类型
期刊论文 [11]
会议论文 [1]
发表日期
2022 [2]
2021 [1]
2018 [2]
2016 [1]
2015 [3]
2013 [1]
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Discovery of novel Thieno[2,3-d]imidazole derivatives as agonists of human STING for antitumor immunotherapy using systemic administration
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 238, 页码: 16
作者:
Niu, Jing
;
Bai, Hudagula
;
Li, Zizhou
;
Gao, Yuzhe
;
Zhang, Yan
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/08/16
STING
cGAS
Non-cyclic dinucleotides (non-CDNs)
Systemic administration
Antitumor immunotherapy
Rh(III)-Catalyzed C-H Activation and [4+1+1] Sequential Cyclization Cascade to Give Highly Fused Indano[1,2-b]azirines
期刊论文
OAI收割
ORGANIC LETTERS, 2022, 页码: 5
作者:
Zheng, Fuqiang
;
Zhou, Jianhui
;
Fang, Feifei
;
Li, Jiyuan
;
Wang, Jing
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2022/08/30
PARP14 inhibits microglial activation via LPAR5 to promote post-stroke functional recovery
期刊论文
OAI收割
AUTOPHAGY, 2021, 卷号: 17, 期号: 10, 页码: 2905-2922
作者:
Tang, Ying
;
Liu, Jinchang
;
Wang, Yu
;
Yang, Li
;
Han, Bing
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2022/01/04
Autophagy
functional recovery
ischemic stroke
lysophosphatidic acid receptor 5
microglial activation
poly (ADP-ribose) polymerase 14
Both Hypo-Connectivity and Hyper-Connectivity of the Insular Subregions Associated With Severity in Children With Autism Spectrum Disorders.
期刊论文
OAI收割
FRONTIERS IN NEUROSCIENCE, 2018
作者:
Zhou, Zhifeng
;
Gan, Yungen
;
Hu, Qingmao
;
Xu, Jinping
;
Wang, Hongwei
  |  
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2019/01/31
Functional connectivity of the insular sub_regions associated with severity in children with ASD
会议论文
OAI收割
新加坡, 2018
作者:
Qingmao Hu
;
Ziyun Xu
;
Zhenhui Zhou
;
Yungen Gan
;
Jinping Xu
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/31
Design, synthesis and biological evaluation of novel tetrahydroisoquinoline quaternary derivatives as peripheral kappa-opioid receptor agonists
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: 13, 页码: 2964-2970
作者:
Guo, Ting
;
Gan, Zongjie
;
Chen, Jie
;
Wang, Dechuan
;
He, Ling
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
Tetrahydroisoquinoline quaternary derivatives
Peripheral
kappa-Opioid receptor agonists
Fluorescent Coumarin-Artemisinin Conjugates as Mitochondria-Targeting Theranostic Probes for Enhanced Anticancer Activities
期刊论文
OAI收割
CHEMISTRY-A EUROPEAN JOURNAL, 2015, 卷号: 21, 期号: 48, 页码: 17415-17421
作者:
Zhang, Xu
;
Ba, Qian
;
Gu, Zhanni
;
Guo, Diliang
;
Zhou, Yu
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
apoptosis
cancer
drug delivery
imaging agents
theranostic probes
novelopioidreceptoragonistmb1cohproducespotentanalgesiawithlessdepressionandsedation
期刊论文
OAI收割
actapharmacologicasinica, 2015, 卷号: 36, 期号: 5, 页码: 565
作者:
Zhang Lesha
;
Wang Jun
;
Chen Jianchun
;
Tao Yimin
;
Wang Yuhua
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/07/01
κ-opioid receptor
MB-1C-OH
(-)U50
488H
Nor-BNI
morphine
pain
acetic acid-induced writhing
formalin test
depression
sedation
Novel κ-opioid receptor agonist MB-1C-OH produces potent analgesia with less depression and sedation
期刊论文
OAI收割
Acta Pharmacologica Sinica, 2015, 卷号: 36, 期号: 5, 页码: 565
作者:
Zhang Lesha
;
Wang Jun
;
Chen Jianchun
;
Tao Yimin
;
Wang Yuhua
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/12/24
κ-opioid receptor
MB-1C-OH
(-)U50
488H
Nor-BNI
morphine
pain
acetic acid-induced writhing
formalin test
depression
sedation
Design, synthesis and biological evaluation of novel 4-anilinoquinazolines with C-6 urea-linked side chains as inhibitors of the epidermal growth factor receptor
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 24, 页码: 7988-7998
作者:
Zhang, Xu
;
Peng, Ting
;
Ji, Xun
;
Li, Jian
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2019/01/08
EGFR inhibitor
EGFR T790M/L858R
Binding mode
Irreversible EGFR inhibitor