中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [8]
采集方式
OAI收割 [8]
内容类型
期刊论文 [6]
会议论文 [2]
发表日期
2019 [3]
2017 [1]
2016 [2]
2014 [2]
学科主题
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Current trends in drug metabolism and pharmacokinetics
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 6, 页码: 1113-1144
作者:
Li, Yuhua
;
Meng, Qiang
;
Yang, Mengbi
;
Liu, Dongyang
;
Hou, Xiangyu
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2020/07/01
Pharmacokinetics
Drug metabolism
Drug-drug interactions
Modeling
Metabolizing enzymes
Transporters
Nuclear receptors
Noncoding RNAs
Intestinal and hepatic biotransformation of pyrrolizidine alkaloid N-oxides to toxic pyrrolizidine alkaloids
期刊论文
OAI收割
ARCHIVES OF TOXICOLOGY, 2019, 卷号: 93, 期号: 8, 页码: 2197-2209
作者:
Yang, Mengbi
;
Ma, Jiang
;
Ruan, Jianqing
;
Ye, Yang
;
Fu, Peter Pi-Cheng
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/07/01
Pyrrolizidine alkaloid N-oxides
Pyrrolizidine alkaloids
Pyrrolizidine alkaloid N-oxide toxicity
Biotransformation of pyrrolizidine alkaloid N-oxides
Microbiota biotransformation
currenttrendsindrugmetabolismandpharmacokinetics
期刊论文
OAI收割
actapharmaceuticasinicab, 2019, 卷号: 9, 期号: 6, 页码: 1113
作者:
Liu Dongyang
;
Hou Xiangyu
;
Tang Lan
;
Wang Xin
;
Lyu Yuanfeng
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/07/01
ARYL-HYDROCARBON RECEPTOR
BLOOD-BRAIN-BARRIER
ORGANIC ANION TRANSPORTERS
CHRONIC KIDNEY-DISEASE
PREGNANE-X-RECEPTOR
P-GLYCOPROTEIN
QUANTITATIVE PREDICTION
CYTOCHROME-P450 ENZYMES
DOWN-REGULATION
IN-VIVO
Pharmacokinetics
Drug metabolism
Drug-drug interactions
Modeling
Metabolizing enzymes
Transporters
Nuclear receptors
Noncoding RNAs
First evidence of pyrrolizidine alkaloid N-oxide-induced hepatic sinusoidal obstruction syndrome in humans
期刊论文
OAI收割
ARCHIVES OF TOXICOLOGY, 2017, 卷号: 91, 期号: 12, 页码: 3913-3925
作者:
Yang, Mengbi
;
Ruan, Jianqing
;
Gao, Hong
;
Li, Na
;
Ma, Jiang
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
Pyrrolizidine alkaloid N-oxide
Pyrrolizidine alkaloid
Hepatic sinusoidal obstruction syndrome
Pyrrole-protein adduct
Biotransformation
Toxicokinetic
Cytotoxicity of pyrrolizidine alkaloid in human hepatic parenchymal and sinusoidal endothelial cells: Firm evidence for the reactive metabolites mediated pyrrolizidine alkaloid-induced hepatotoxicity
期刊论文
OAI收割
Chemico-biological interactions, 2016, 卷号: 243, 页码: 119-26
作者:
Yang, Mengbi
;
Ruan, Jianqing
;
Fu, Peter P
;
Lin, Ge
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
Comparative study on the pharmacokinetic profiles of hepatotoxic pyrrolizidine alkaloids and their N-oxides
会议论文
OAI收割
作者:
Yang, Mengbi
;
Ye, Yang
;
Lin, Ge
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/01/08
Metabolic Activation of Pyrrolizidine Alkaloids: Insights into the Structural and Enzymatic Basis
期刊论文
OAI收割
CHEMICAL RESEARCH IN TOXICOLOGY, 2014, 卷号: 27, 期号: 6, 页码: 1030-1039
作者:
Ruan, Jianqing
;
Yang, Mengbi
;
Fu, Peter
;
Ye, Yang
;
Lin, Ge
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
INTESTINAL ABSORPTION OF PYRROLIZIDINE ALKALOIDS AND THEIR N-OXIDES
会议论文
OAI收割
作者:
Yang, Mengbi
;
Ruan, Jianqing
;
Ye, Yang
;
Lin, Ge
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08