中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
昆明植物研究所 [153]
上海药物研究所 [85]
近代物理研究所 [52]
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期刊论文 [682]
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One stone two birds: Introducing piperazine into a series of nucleoside derivatives as potent and selective PRMT5 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 18
作者:
Li, Huaxuan
;
Yang, Hong
;
Liu, Li
;
Zheng, Jiahong
;
Shi, Qiongyu
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/12/11
Protein arginine methyltransferase 5
Nucleoside derivatives
Piperazine
Metabolic stability
Symmetric dimethylarginines
GRB 240529A: A Tale of Two Shocks
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2024, 卷号: 976, 期号: 2
作者:
Sun, Tian-Rui
;
Geng, Jin-Jun
;
Yan, Jing-Zhi
;
Hu, You-Dong
;
Wu, Xue-Feng
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/12/02
Discovery of CZL-046 with an (
S
)-3-Fluoropyrrolidin-2-one Scaffold as a p300 Bromodomain Inhibitor for the Treatment of Multiple Myeloma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 20, 页码: 18606-18628
作者:
Chen, Zonglong
;
Yang, Hong
;
Zhang, Yan
;
Lyu, Xiaodong
;
Shi, Qiongyu
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/11/05
Gut microbiota-brain bile acid axis orchestrates aging-related neuroinflammation and behavior impairment in mice
期刊论文
OAI收割
PHARMACOLOGICAL RESEARCH, 2024, 卷号: 208, 页码: 15
作者:
Ma, Junli
;
Li, Mingxiao
;
Bao, Yiyang
;
Huang, Wenjin
;
He, Xiaofang
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/10/21
aging
brain
neuro-impairment
bile acid
gut microbiota
Efficacy and safety of
Bacteroides fragilis
BF839 for pediatric autism spectrum disorder: a randomized clinical trial
期刊论文
OAI收割
FRONTIERS IN NUTRITION, 2024, 卷号: 11, 页码: 12
作者:
Lin, Chu-hui
;
Zeng, Ting
;
Lu, Cui-wei
;
Li, De-yang
;
Liu, Yi-ying
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/10/14
autism spectrum disorder in children
probiotics
Bacteroides fragilis BF839
abnormal behavior
gastrointestinal symptoms
Transcriptomic decoding of regional cortical vulnerability to major depressive disorder
期刊论文
OAI收割
COMMUNICATIONS BIOLOGY, 2024, 卷号: 7, 期号: 1, 页码: 12
作者:
Zhu, Jiajia
;
Chen, Xiao
;
Lu, Bin
;
Li, Xue-Ying
;
Wang, Zi-Han
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/09/10
Anti-HBV Activities of Cembranoids from the South China Sea Soft Coral
Sinularia pedunculata
and Their Structure Activity Relationship
期刊论文
OAI收割
CHEMISTRY & BIODIVERSITY, 2024, 页码: 8
作者:
Huang, Chao
;
Jin, Yang
;
Sun, Ruo-Nan
;
Hu, Kong-Ying
;
Yao, Li-Gong
  |  
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2024/08/22
Hepatitis B Virus
cembranoid
anti-HBV activity
structure-activity relationship
ENI/Xp enhancer/promoter
FXR activation remodels hepatic and intestinal transcriptional landscapes in metabolic dysfunction-associated steatohepatitis
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 15
作者:
Wen, Ying-quan
;
Zou, Zi-yuan
;
Zhao, Guan-guan
;
Zhang, Meng-jiao
;
Zhang, Yong-xin
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/08/22
MASLD/MASH
FXR
transcriptome
gut-liver axis
agonist
Oncogenic KRAS Induces Arginine Auxotrophy and Confers a Therapeutic Vulnerability to SLC7A1 Inhibition in Non-Small Cell Lung Cancer
期刊论文
OAI收割
CANCER RESEARCH, 2024, 卷号: 84, 期号: 12, 页码: 1963-1977
作者:
Gai, Xiameng
;
Liu, Yingluo
;
Lan, Xiaojing
;
Chen, Luoyi
;
Yuan, Tao
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/08/20
Cross-ancestry genome-wide association studies of brain imaging phenotypes
期刊论文
OAI收割
NATURE GENETICS, 2024, 页码: 31
作者:
Fu, Jilian
;
Zhang, Quan
;
Wang, Jianhua
;
Wang, Meiyun
;
Zhang, Bing
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/06/29