中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [168]
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期刊论文 [290]
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De Novo Design of Structure-Tunable Multivalent Targeting Chimeras for Tumor-Targeted PD-L1 Degradation and Potentiated Cancer Immunotherapy
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 17
作者:
Zhou, Huiling
;
Hou, Bo
;
Shan, Yiming
;
Huang, Lujia
;
Chen, Fangmin
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/06/23
Combinatory therapy, Immune checkpoint blockade, Multivalent targeting chimeras
Tumor microenvironment
Tumor-specific PD-L1 degradation
Enhancing anti-tumor immunity through intratumoral combination therapy with amphiphilic conjugates of oxaliplatin and imidazoquinoline TLR7/8 agonist
期刊论文
OAI收割
RSC ADVANCES, 2025, 卷号: 15, 期号: 15, 页码: 11662-11674
作者:
Verschuere, Hanne
;
Kasmi, Sabah
;
Nuhn, Lutz
;
D'Almeida, Senan Mickael
;
Zhu, Qiwen
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/06/23
Tailoring nanovectors for optimal neoantigen vaccine efficacy
期刊论文
OAI收割
JOURNAL OF MATERIALS CHEMISTRY B, 2025, 卷号: 13, 期号: 13, 页码: 4045-4058
作者:
Zheng, Youshi
;
Wang, Bing
;
Cai, Zhixiong
;
Lai, Zisen
;
Yu, Haijun
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/04/24
Self-Oxygenating PROTAC Microneedle for Spatiotemporally-Confined Protein Degradation and Enhanced Glioblastoma Therapy
期刊论文
OAI收割
ADVANCED MATERIALS, 2025, 页码: 13
作者:
Jiang, Xingyu
;
Lai, Yi
;
Xia, Wenzheng
;
Yang, Wenfang
;
Wang, Junjue
  |  
收藏
  |  
浏览/下载:0/0
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提交时间:2025/04/24
acid-activatable photodynamic therapy
double-layered microneedle
glioblastoma therapy
light-activatable PROTAC prodrug
protein degradation
Targeting Mesothelin Enhances Personalized Neoantigen Vaccine Induced Antitumor Immune Response in Orthotopic Pancreatic Cancer Mouse Models
期刊论文
OAI收割
ADVANCED SCIENCE, 2025, 页码: 17
作者:
Cai, Zhixiong
;
Li, Zhenli
;
Zhong, Wenting
;
Lin, Fangzhou
;
Dong, Xiuqing
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2025/04/01
apCAFs
immunotherapy
mesothelin
neoantigen vaccine
pancreatic cancer
EGCG-enabled Deep Tumor Penetration of Phosphatase and Acidity Dual-responsive Nanotherapeutics for Combinatory Therapy of Breast Cancer
期刊论文
OAI收割
SMALL, 2024, 页码: 20
作者:
Zhou, Mengxue
;
Zhou, Chuang
;
Geng, Huan
;
Huang, Zhiwei
;
Lin, Zhiyuan
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/12/16
chemo/chemodynamic therapy
EGCG
nanomedicine
TGF-beta signaling
triple-negative breast cancer
Tumor-specific delivery of clickable inhibitor for PD-L1 degradation and mitigating resistance of radioimmunotherapy
期刊论文
OAI收割
SCIENCE ADVANCES, 2024, 卷号: 10, 期号: 46, 页码: 17
作者:
Hou, Bo
;
Ye, Jiayi
;
Huang, Lujia
;
Cheng, Wenhao
;
Chen, Fangmin
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/12/16
The advance of ultrasound-enabled diagnostics and therapeutics
期刊论文
OAI收割
JOURNAL OF CONTROLLED RELEASE, 2024, 卷号: 375, 页码: 1-19
作者:
Han, Biying
;
Liu, Yan
;
Zhou, Qianqian
;
Yu, Yuting
;
Liu, Xingxing
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/01/14
Ultrasonic medicine
Sonosensitizer
Sonodynamic therapy
Cavitation effect
Deep penetration
Dynamic polyphenol nanoparticles boost cuproptosis-driven metalloimmunotherapy of breast cancer
期刊论文
OAI收割
NANO TODAY, 2024, 卷号: 58, 页码: 12
作者:
Zhang, Huijuan
;
Chen, Fangmin
;
Cheng, Wenhao
;
Lai, Yi
;
Hou, Bo
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/10/09
Polyphenol
Cuproptosis
Dynamic covalent bond
Cancer metalloimmunotherapy
Tumor immune microenvironment
Engineering PEG10assembled endogenous virus-like particles with genetically encoded neoantigen peptides for cancer vaccination
期刊论文
OAI收割
ELIFE, 2024, 卷号: 13, 页码: 22
作者:
Tang, Ruijing
;
Guo, Luobin
;
Wei, Tingyu
;
Chen, Tingting
;
Yang, Huan
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/10/21
PEG10
CpG-ODN
neoantigen
Mouse