中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [7]
南海海洋研究所 [2]
宁波材料技术与工程研... [2]
大连化学物理研究所 [2]
深海科学与工程研究所 [2]
力学研究所 [1]
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采集方式
OAI收割 [18]
内容类型
期刊论文 [18]
发表日期
2024 [4]
2023 [4]
2022 [3]
2020 [5]
2012 [2]
学科主题
Chemistry [2]
Electroche... [1]
Energy & F... [1]
物理化学 [1]
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浏览/检索结果:
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An updated patent review of SOS1 inhibitors (2022-present)
期刊论文
OAI收割
EXPERT OPINION ON THERAPEUTIC PATENTS, 2024, 页码: 15
作者:
Zhou, Guizhen
;
Zhou, Chuan
;
Ma, Xinyi
;
Xu, Jiahang
;
Zhou, Zehui
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/12/11
SOS1
KRAS
cancer
inhibitor
drug discovery
Discovery of Preclinical Candidate AD1058 as a Highly Potent, Selective, and Brain-Penetrant ATR Inhibitor for the Treatment of Advanced Malignancies
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 15, 页码: 12735-12759
作者:
Liu, Zhi
;
Jiang, Kailong
;
Liu, Yan
;
Li, Junfei
;
Huang, Siqi
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/09/26
Design, synthesis, and bioevaluation of SOS1 PROTACs derived from pyrido [2,3-
d
]pyrimidin-7-one-based SOS1 inhibitor
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 107, 页码: 9
作者:
Wang, Kun
;
Zhou, Zehui
;
Ma, Xinyi
;
Xu, Jiahang
;
Xu, Wangyang
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/07/12
SOS1
KRAS mutation
PROTAC
Anti-cancer activity
UAV-Assisted Dynamic Avatar Task Migration for Vehicular Metaverse Services: A Multi-Agent Deep Reinforcement Learning Approach
期刊论文
OAI收割
IEEE/CAA Journal of Automatica Sinica, 2024, 卷号: 11, 期号: 2, 页码: 430-445
作者:
Jiawen Kang
;
Junlong Chen
;
Minrui Xu
;
Zehui Xiong
;
Yutao Jiao
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2024/01/23
Avatar
blockchain
metaverses
multi-agent deep reinforcement learning
transformer
UAVs
Genetic adaptations of sea anemone to hydrothermal environment
期刊论文
OAI收割
SCIENCE ADVANCES, 2023, 卷号: 9, 期号: 42, 页码: 1-15
作者:
Yang,Zhou
;
Helu,Liu
;
Chenguang,Feng
;
Zaiqing,Lu
;
Jun,Liu
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2023/11/03
Discovery of a Potent, Cooperative, and Selective SOS1 PROTAC ZZ151 with In Vivo Antitumor Efficacy in KRAS-Mutant Cancers
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 6, 页码: 4197-4214
作者:
Zhou, Zehui
;
Zhou, Guizhen
;
Zhou, Chuan
;
Fan, Zisheng
;
Cui, Rongrong
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/03/27
Seismic Monitoring of Machinery through Noise Interferometry of Distributed Acoustic Sensing
期刊论文
OAI收割
SEISMOLOGICAL RESEARCH LETTERS, 2023, 卷号: 94, 期号: 2A, 页码: 637-645
作者:
Xiao, Zhuo
;
Li, Chao
;
Zhou, Yong
;
Xu, Min
;
Yang, Huayong
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/08/22
Design, Synthesis, and Bioevaluation of Pyrido[2,3-d]pyrimidin-7-ones as Potent SOS1 Inhibitors
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2023, 页码: 183-190
作者:
Liu, Meiying
;
Zhou, Guizhen
;
Su, Wenhong
;
Gu, Yuejiao
;
Gao, Mingshan
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/03/27
KRAS mutation
SOS1-KRAS interaction
SOS1 inhibitor
combination therapy
Adaptation and evolution of the sea anemone Alvinactis sp. to deep-sea hydrothermal vents: A comparison using transcriptomes
期刊论文
OAI收割
Ecology and Evolution, 2022, 卷号: e9309, 页码: 1-12
作者:
Zehui Xu
;
Zeyu Chen
;
Haibin Zhang
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2022/11/25
adaptation
chemosynthetic ecosystem
endocytosis
hydrothermal vent
peroxisome
positively selected gene
sea anemone
Control reattachment of backward-facing step flow using a row of mini-jets in recirculation bubble
期刊论文
OAI收割
PHYSICS OF FLUIDS, 2022, 卷号: 34, 期号: 8, 页码: 7
作者:
Mu, Zehui
;
Zhou, Wenya
;
Xu, Duo
;
Gao, Nan
;
Xu D(徐多)
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2022/09/16