中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
昆明植物研究所 [187]
近代物理研究所 [99]
上海药物研究所 [81]
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期刊论文 [1020]
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2024 [17]
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One stone two birds: Introducing piperazine into a series of nucleoside derivatives as potent and selective PRMT5 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 18
作者:
Li, Huaxuan
;
Yang, Hong
;
Liu, Li
;
Zheng, Jiahong
;
Shi, Qiongyu
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/12/11
Protein arginine methyltransferase 5
Nucleoside derivatives
Piperazine
Metabolic stability
Symmetric dimethylarginines
Auto-RapTAC: A Versatile and Sustainable Platform for the Automated Rapid Synthesis and Evaluation of PROTAC
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 15
作者:
Chen, Jiexuan
;
Wu, Mingfei
;
Mo, Jun
;
Hong, Ju
;
Wang, Wei
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/04/01
GRB 240529A: A Tale of Two Shocks
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2024, 卷号: 976, 期号: 2
作者:
Sun, Tian-Rui
;
Geng, Jin-Jun
;
Yan, Jing-Zhi
;
Hu, You-Dong
;
Wu, Xue-Feng
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/12/02
Ecological restoration enhances dryland carbon stock by reducing surface soil carbon loss due to wind erosion
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2024, 卷号: 121, 期号: 46, 页码: 10
作者:
Song, Jian
;
Wan, Shiqiang
;
Zhang, Kesheng
;
Hong, Songbai
;
Xia, Jianyang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/02/06
carbon neutrality
climate solutions
plant productivity
soil carbon
soil erosion
Discovery of CZL-046 with an (
S
)-3-Fluoropyrrolidin-2-one Scaffold as a p300 Bromodomain Inhibitor for the Treatment of Multiple Myeloma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 20, 页码: 18606-18628
作者:
Chen, Zonglong
;
Yang, Hong
;
Zhang, Yan
;
Lyu, Xiaodong
;
Shi, Qiongyu
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/11/05
Transcriptomic decoding of regional cortical vulnerability to major depressive disorder
期刊论文
OAI收割
COMMUNICATIONS BIOLOGY, 2024, 卷号: 7, 期号: 1, 页码: 12
作者:
Zhu, Jiajia
;
Chen, Xiao
;
Lu, Bin
;
Li, Xue-Ying
;
Wang, Zi-Han
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/09/10
FXR activation remodels hepatic and intestinal transcriptional landscapes in metabolic dysfunction-associated steatohepatitis
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 15
作者:
Wen, Ying-quan
;
Zou, Zi-yuan
;
Zhao, Guan-guan
;
Zhang, Meng-jiao
;
Zhang, Yong-xin
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/08/22
MASLD/MASH
FXR
transcriptome
gut-liver axis
agonist
Cross-ancestry genome-wide association studies of brain imaging phenotypes
期刊论文
OAI收割
NATURE GENETICS, 2024, 页码: 31
作者:
Fu, Jilian
;
Zhang, Quan
;
Wang, Jianhua
;
Wang, Meiyun
;
Zhang, Bing
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2024/06/29
CSST large-scale structure analysis pipeline: I. Constructing reference mock galaxy redshift surveys (vol 529, pg 4015, 2024)
期刊论文
OAI收割
MONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY, 2024, 卷号: 531, 期号: 1, 页码: 1243-1243
作者:
Gu, Yizhou
;
Yang, Xiaohu
;
Han, Jiaxin
;
Wang, Yirong
;
Li, Qingyang
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/06/11
Co-inhibition of BET and NAE enhances BIM-dependent apoptosis with augmented cancer therapeutic efficacy
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2024, 卷号: 223, 页码: 17
作者:
Zhang, Qian
;
Wu, Qian
;
Huan, Xia-Juan
;
Song, Shan -Shan
;
Bao, Xu-Bin
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/06/27
BET inhibitor
NAE inhibitor
BIM
Apoptosis
Combination therapy