中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [9]
武汉岩土力学研究所 [4]
大连化学物理研究所 [2]
中国科学院大学 [1]
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OAI收割 [14]
iSwitch采集 [2]
内容类型
期刊论文 [14]
会议论文 [2]
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2024 [4]
2023 [3]
2022 [2]
2019 [2]
2017 [2]
2015 [1]
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学科主题
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浏览/检索结果:
共16条,第1-10条
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Ginkgetin Alleviates Inflammation and Senescence by Targeting STING
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 15
作者:
Liu, Yadan
;
Ye, Jialin
;
Fan, Zisheng
;
Wu, Xiaolong
;
Zhang, Yinghui
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/12/16
cGAS-STING signaling
Ginkgetin
senescence
STING inhibitor
target identification
An updated patent review of SOS1 inhibitors (2022-present)
期刊论文
OAI收割
EXPERT OPINION ON THERAPEUTIC PATENTS, 2024, 页码: 15
作者:
Zhou, Guizhen
;
Zhou, Chuan
;
Ma, Xinyi
;
Xu, Jiahang
;
Zhou, Zehui
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/12/11
SOS1
KRAS
cancer
inhibitor
drug discovery
Design, synthesis, and bioevaluation of SOS1 PROTACs derived from pyrido [2,3-
d
]pyrimidin-7-one-based SOS1 inhibitor
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 107, 页码: 9
作者:
Wang, Kun
;
Zhou, Zehui
;
Ma, Xinyi
;
Xu, Jiahang
;
Xu, Wangyang
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/07/12
SOS1
KRAS mutation
PROTAC
Anti-cancer activity
Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRAS
G12D
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1147-1167
作者:
Zhou, Chuan
;
Fan, Zisheng
;
Gu, Yuejiao
;
Ge, Zhiming
;
Tao, Zhaofan
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/02/27
Discovery of a Potent, Cooperative, and Selective SOS1 PROTAC ZZ151 with In Vivo Antitumor Efficacy in KRAS-Mutant Cancers
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 6, 页码: 4197-4214
作者:
Zhou, Zehui
;
Zhou, Guizhen
;
Zhou, Chuan
;
Fan, Zisheng
;
Cui, Rongrong
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2024/03/27
Design, Synthesis, and Biological Evaluation of Bipyridazine Derivatives as Stimulator of Interferon Genes (STING) Receptor Agonists
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 5, 页码: 3327-3347
作者:
Shan, Bin
;
Hou, Hui
;
Zhang, Keke
;
Li, Rui
;
Shen, Chang
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/03/27
Design, Synthesis, and Bioevaluation of Pyrido[2,3-d]pyrimidin-7-ones as Potent SOS1 Inhibitors
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2023, 页码: 183-190
作者:
Liu, Meiying
;
Zhou, Guizhen
;
Su, Wenhong
;
Gu, Yuejiao
;
Gao, Mingshan
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/03/27
KRAS mutation
SOS1-KRAS interaction
SOS1 inhibitor
combination therapy
Discovery of ARF1-targeting inhibitor demethylzeylasteral as a potential agent against breast cancer
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 5, 页码: 2619-2622
作者:
Chang, Jie
;
Yang, Ruirui
;
Chen, Lifan
;
Fan, Zisheng
;
Zhou, Jingyi
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2022/08/16
ADP-ribosylation factor 1
Breast cancer
Demethylzeylasteral
Virtual screening
Discovery of the First-in-Class Agonist-Based SOS1 PROTACs Effective in Human Cancer Cells Harboring Various KRAS Mutations
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 5, 页码: 3923-3942
作者:
Zhou, Chuan
;
Fan, Zisheng
;
Zhou, Zehui
;
Li, Yupeng
;
Cui, Rongrong
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2022/06/15
Oxygen vacancy modulated Ti2Nb10O29-x embedded onto porous bacterial cellulose carbon for highly efficient lithium ion storage
期刊论文
OAI收割
NANO ENERGY, 2019, 卷号: 58, 页码: 355-364
作者:
Wang, Xiuli
;
Yu, Yan
;
Pan, Guoxiang
;
Tu, Jiangping
;
Xia, Xinhui
  |  
收藏
  |  
浏览/下载:87/0
  |  
提交时间:2019/06/20
Bacterial cellulose carbon
Porous carbon fibres
Ti2Nb10O29
Oxygen vacancy
Lithium ions batteries