中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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近代物理研究所 [48]
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期刊论文 [407]
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One stone two birds: Introducing piperazine into a series of nucleoside derivatives as potent and selective PRMT5 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 18
作者:
Li, Huaxuan
;
Yang, Hong
;
Liu, Li
;
Zheng, Jiahong
;
Shi, Qiongyu
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/12/11
Protein arginine methyltransferase 5
Nucleoside derivatives
Piperazine
Metabolic stability
Symmetric dimethylarginines
Auto-RapTAC: A Versatile and Sustainable Platform for the Automated Rapid Synthesis and Evaluation of PROTAC
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 15
作者:
Chen, Jiexuan
;
Wu, Mingfei
;
Mo, Jun
;
Hong, Ju
;
Wang, Wei
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/04/01
Ecological restoration enhances dryland carbon stock by reducing surface soil carbon loss due to wind erosion
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2024, 卷号: 121, 期号: 46, 页码: 10
作者:
Song, Jian
;
Wan, Shiqiang
;
Zhang, Kesheng
;
Hong, Songbai
;
Xia, Jianyang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/02/06
carbon neutrality
climate solutions
plant productivity
soil carbon
soil erosion
Gut microbiota-brain bile acid axis orchestrates aging-related neuroinflammation and behavior impairment in mice
期刊论文
OAI收割
PHARMACOLOGICAL RESEARCH, 2024, 卷号: 208, 页码: 15
作者:
Ma, Junli
;
Li, Mingxiao
;
Bao, Yiyang
;
Huang, Wenjin
;
He, Xiaofang
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/10/21
aging
brain
neuro-impairment
bile acid
gut microbiota
Cross-ancestry genome-wide association studies of brain imaging phenotypes
期刊论文
OAI收割
NATURE GENETICS, 2024, 页码: 31
作者:
Fu, Jilian
;
Zhang, Quan
;
Wang, Jianhua
;
Wang, Meiyun
;
Zhang, Bing
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/06/29
Article Activation of hepatic adenosine A1 receptor ameliorates MASH via inhibiting SREBPs maturation
期刊论文
OAI收割
CELL REPORTS MEDICINE, 2024, 卷号: 5, 期号: 3, 页码: 25
作者:
Zhu, Weize
;
Hong, Ying
;
Tong, Zhaowei
;
He, Xiaofang
;
Li, Yan
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2024/06/27
Sesquiterpenoids and Cytochalasins with Immunosuppressive Activity from
Sonchus wightianus
期刊论文
OAI收割
CHEMISTRY & BIODIVERSITY, 2024, 页码: 9
作者:
Xie, Zhi-Xiang
;
Cui, Yong-Sheng
;
Liu, Xi-Hong
;
Yao, Jia-Ying
;
He, Shi-Jun
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/05/07
Sonchus wightianus
guaiane-type sesquiterpenoid
cytochalasin
electronic circular dichroism
immunosuppressive activity
Ecosystem responses dominate the trends of annual gross primary productivity over terrestrial ecosystems of China during 2000-2020
期刊论文
OAI收割
AGRICULTURAL AND FOREST METEOROLOGY, 2023, 卷号: 343, 页码: 109758
作者:
Zhu, Xian-Jin
;
Yu, Gui-Rui
;
Chen, Zhi
;
Zhang, Wei-Kang
;
Han, Lang
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2023/12/04
Carbon cycles
Eddy covariance
Terrestrial ecosystems
Machine learning
Ecosystem responses
Tetrandrine synergizes with MAPK inhibitors in treating KRAS-mutant pancreatic ductal adenocarcinoma via collaboratively modulating the TRAIL-death receptor axis
期刊论文
OAI收割
PHARMACOLOGICAL RESEARCH, 2023, 卷号: 197, 页码: 12
作者:
Tang, Shuai
;
Duan, Yichen
;
Yuan, Tao
;
Hu, Yutinh
;
Yuan, Liang
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/12/11
KRAS
Pancreatic ductal adenocarcinoma
MAPK pathway
Tetrandrine
TRAIL
Death receptors
Development of a multiple convolutional neural network-facilitated diagnostic screening program for immunofluorescence images of IgA nephropathy and idiopathic membranous nephropathy
期刊论文
OAI收割
CLINICAL KIDNEY JOURNAL, 2023, 页码: 11
作者:
Xia, Peng
;
Lv, Zhilong
;
Wen, Yubing
;
Zhang, Baichuan
;
Zhao, Xuesong
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2023/12/04
convolutional neural network
idiopathic membranous nephropathy
IgA nephropathy
immunofluorescence