机构

• 上海药物研究所 [21]
• 上海光学精密机械研... [16]
• 西北高原生物研究所 [11]
• 动物研究所 [6]
• 宁波材料技术与工程研... [5]
• 地理科学与资源研究所 [2]
• 更多

采集方式

• OAI收割 [74]

内容类型

• 期刊论文 [68]
• 会议论文 [6]

发表日期

• 2024 [4]
• 2023 [7]
• 2022 [5]
• 2021 [8]
• 2020 [11]
• 2019 [8]
• 更多

学科主题

• 物理化学 [1]

筛选

浏览/检索结果: 共74条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery of N-Benzylpiperidinol derivatives as USP7 inhibitors against Hematology 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 153, 页码: 13 作者:  Pan, Youlu;  Chen, Haifeng;  Fu, Jingfeng;  Zhang, Jingyu;  Wang, Peipei   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/10/21 Discovery of Novel 2-Aminopyridine-Based and 2-Aminopyrimidine-Based Derivatives as Potent CDK/HDAC Dual Inhibitors for the Treatment of Refractory Solid Tumors and Hematological Malignancies 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 17, 页码: 15220-15245 作者:  Saidahmatov, Abdusaid;  Li, Jianan;  Xu, Shihao;  Hu, Xiaobei;  Gao, Xiangqian   |  收藏  |  浏览/下载：20/0  |  提交时间：2024/10/21 Discovery of a Highly Potent, Selective and Efficacious USP7 Degrader for the Treatment of Acute Lymphoblastic Leukemia 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 20 作者:  Xu, Miaomiao   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/08/22 Discovery of potent small molecule ubiquitin-specific protease 10 inhibitors with anti-hepatocellular carcinoma activity through regulating YAP expression 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 272, 页码: 21 作者:  Lu, Yang;  Gao, Jian;  Wang, Peipei;  Chen, Haifeng;  He, Xinjun   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/07/12 Hepatocellular carcinoma  Ubiquitin-specific protease 10  Deubiquitination  Selectivity   Discovery of 5-trifluoromethyl-2-aminopyrimidine derivatives as potent dual inhibitors of FLT3 and CHK1 期刊论文  OAI收割 RSC MEDICINAL CHEMISTRY, 2023, 页码: 14 作者:  Deng, Minjie;  Gao, Yue;  Wang, Peipei;  Du, Wenjing;  Xu, Gaoya   |  收藏  |  浏览/下载：24/0  |  提交时间：2024/02/19 Design, synthesis and biological evaluation of 2-aminopyrimidine derivatives as potent FLT3 inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 96, 页码: 5 作者:  Lian, Xuanmin;  Gao, Yue;  Li, Xuemei;  Wang, Peipei;  Tong, Lexian   |  收藏  |  浏览/下载：22/0  |  提交时间：2023/12/11 2-aminopyrimidine  FLT3 inhibitors  MV4-11  FLT3 mutations   Discovery of 2-Aminopyrimidine Derivatives as Potent Dual FLT3/CHK1 Inhibitors with Significantly Reduced hERG Inhibitory Activities 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 23 作者:  Li, Xuemei;  Wang, Peipei;  Wang, Chang;  Jin, Tingting;  Xu, Ran   |  收藏  |  浏览/下载：24/0  |  提交时间：2023/10/17 Discovery of pyrido[4,3-d]pyrimidinone derivatives as novel Wee1 inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 87, 页码: 12 作者:  Ye, Qingqing;  Ma, Jingkun;  Wang, Peipei;  Wang, Chang;  Sun, Mei   |  收藏  |  浏览/下载：19/0  |  提交时间：2023/10/17 Wee1 inhibitor  Scaffold hopping   Design, Synthesis, and Biological Evaluation of 2-Aminothiazole Derivatives as Novel Checkpoint Kinase 1 (CHK1) Inhibitors 期刊论文  OAI收割 CHEMMEDCHEM, 2023, 页码: 19 作者:  Deng, Minjie;  Wang, Peipei;  Long, Xiubing;  Xu, Gaoya;  Wang, Chang   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/04/10 2-aminothiazole  CHK1 inhibitors  antiproliferation  hematologic malignancies  biological activity   Design, synthesis, and evaluation of pyrido.[3,4-b]pyrazin-2(1H)-one derivatives as potent FLT3 inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 79, 页码: 117155 作者:  Sun, Mei;  Wang, Chang;  Wang, Peipei;  Ye, Qingqing;  Zhou, Yubo   |  收藏  |  浏览/下载：19/0  |  提交时间：2024/04/09 FLT3  FLT3-D835Y  Acute myeloid leukemia  Structure -activity relationships