机构

• 上海药物研究所 [13]
• 合肥物质科学研究院 [5]
• 上海营养与健康研究所 [1]

采集方式

• OAI收割 [19]

内容类型

• 期刊论文 [19]

发表日期

• 2023 [5]
• 2022 [4]
• 2021 [2]
• 2019 [1]
• 2018 [1]
• 2017 [3]
• 更多

学科主题

• Hematology [1]

筛选

浏览/检索结果: 共19条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of 5-trifluoromethyl-2-aminopyrimidine derivatives as potent dual inhibitors of FLT3 and CHK1 期刊论文  OAI收割 RSC MEDICINAL CHEMISTRY, 2023, 页码: 14 作者:  Deng, Minjie;  Gao, Yue;  Wang, Peipei;  Du, Wenjing;  Xu, Gaoya   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/02/19 Design, synthesis and biological evaluation of 2-aminopyrimidine derivatives as potent FLT3 inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 96, 页码: 5 作者:  Lian, Xuanmin;  Gao, Yue;  Li, Xuemei;  Wang, Peipei;  Tong, Lexian   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/11 2-aminopyrimidine  FLT3 inhibitors  MV4-11  FLT3 mutations   Discovery of 2-Aminopyrimidine Derivatives as Potent Dual FLT3/CHK1 Inhibitors with Significantly Reduced hERG Inhibitory Activities 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 23 作者:  Li, Xuemei;  Wang, Peipei;  Wang, Chang;  Jin, Tingting;  Xu, Ran   |  收藏  |  浏览/下载：14/0  |  提交时间：2023/10/17 Targeting C/EBP alpha overcomes primary resistance and improves the efficacy of FLT3 inhibitors in acute myeloid leukaemia 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 18 作者:  Wang, Hanlin;  Luo, Guanghao;  Hu, Xiaobei;  Xu, Gaoya;  Wang, Tao   |  收藏  |  浏览/下载：12/0  |  提交时间：2023/10/17 Design, synthesis, and evaluation of pyrido.[3,4-b]pyrazin-2(1H)-one derivatives as potent FLT3 inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 79, 页码: 117155 作者:  Sun, Mei;  Wang, Chang;  Wang, Peipei;  Ye, Qingqing;  Zhou, Yubo   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/04/09 FLT3  FLT3-D835Y  Acute myeloid leukemia  Structure -activity relationships   Dual inhibition of CHK1/FLT3 enhances cytotoxicity and overcomes adaptive and acquired resistance in FLT3-ITD acute myeloid leukemia 期刊论文  OAI收割 LEUKEMIA, 2022, 页码: 11 作者:  Jiang, Kailong;  Li, Xuemei;  Wang, Chang;  Hu, Xiaobei;  Wang, Peipei   |  收藏  |  浏览/下载：19/0  |  提交时间：2023/04/10 Identification of 2-Aminopyrimidine Derivatives as FLT3 Kinase Inhibitors with High Selectivity over c-KIT 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 4, 页码: 3229-3248 作者:  Tong, Lexian;  Wang, Peipei;  Li, Xuemei;  Dong, Xiaowu;  Hu, Xiaobei   |  收藏  |  浏览/下载：18/0  |  提交时间：2022/08/16 Efficient Synthesis and Biological Evaluation of 6-Trifluoroethoxy Functionalized Pteridine Derivatives as EGFR Inhibitors 期刊论文  OAI收割 MEDICINAL CHEMISTRY, 2022, 卷号: 18, 期号: 3, 页码: 353-363 作者:  Lin, Jin;  Zhang, Zemin;  Lin, Xiongqiang;  Chen, Zhendong;  Luc, Tian   |  收藏  |  浏览/下载：26/0  |  提交时间：2022/06/15 Pteridine  derivatives  EGFR  inhibitor  2,2,2-trifluoroethoxy  antitumor activity   BCL-2 inhibitor synergizes with PI3K delta inhibitor and overcomes FLT3 inhibitor resistance in acute myeloid leukaemia 期刊论文  OAI收割 AMERICAN JOURNAL OF CANCER RESEARCH, 2022, 卷号: 12, 期号: 8, 页码: 3829-3842 作者:  Yao, Ming-Yue;  Wang, Ya-Fang;  Zhao, Yu;  Ling, Li-Jun;  He, Ye   |  收藏  |  浏览/下载：19/0  |  提交时间：2022/12/13 Acute myeloid leukaemia  BCL-2  PI3K delta  FLT3  synergistic lethality   Discover Novel Covalent Inhibitors Targeting FLT3 through Hybrid Virtual Screening Strategy 期刊论文  OAI收割 BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2021, 卷号: 44, 期号: 12, 页码: 1872-1877 作者:  Hu, Shengquan;  Liu, Jing;  Chen, Sikang;  Gao, Jian;  Zhou, Yubo   |  收藏  |  浏览/下载：21/0  |  提交时间：2022/06/15 acute myeloid leukemia  FMS-like tyrosine kinase 3  CovDock  hybrid virtual screening  autodock