机构

• 上海药物研究所 [7]

采集方式

• OAI收割 [7]

内容类型

• 期刊论文 [7]

发表日期

• 2016 [2]
• 2015 [1]
• 2014 [1]
• 2013 [1]
• 2012 [2]

学科主题

筛选

浏览/检索结果: 共7条，第1-7条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序题名升序题名降序作者升序作者降序发表日期升序发表日期降序 Discovery and Structure-Activity Relationship Study of 4-Phenoxythiazol-5-carboxamides as Highly Potent TGR5 Agonists 期刊论文  OAI收割 CHEMICAL & PHARMACEUTICAL BULLETIN, 2016, 卷号: 64, 期号: 4, 页码: 326-339 作者:  Chen, Zhixiang;  Ning, Mengmeng;  Zou, Qingan;  Cao, Hua;  Ye, Yangliang   |  收藏  |  浏览/下载：9/0  |  提交时间：2019/01/08 Takeda G-protein-coupled receptor 5 agonist  bioisostere  microsomal clearance  structure-activity relationship   ol3anovellowabsorbedtgr5agonistwithreducedsideeffectsloweredbloodglucoseviadualactionsontgr5activationanddpp4inhibition 期刊论文  OAI收割 actapharmacologicasinica, 2016, 卷号: 000, 期号: 010, 页码: 1359 作者:  Ma Shanyao;  Ning Mengmeng;  Zou Qingan;  Feng Ying;  Ye Yangliang   |  收藏  |  浏览/下载：11/0  |  提交时间：2020/07/01 OL3  MN6  linagliptin  TGR5 agonist  DPP4 inhibitor  GLP-1  low-absorbed  gallbladder filling  type 2 diabetes mellitus   Discovery of Intestinal Targeted TGR5 Agonists for the Treatment of Type 2 Diabetes 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 58, 期号: 8, 页码: 3315-3328 作者:  Duan, Hongliang;  Ning, Mengmeng;  Zou, Qingan;  Ye, Yangliang;  Feng, Ying   |  收藏  |  浏览/下载：13/0  |  提交时间：2019/01/08 4-Benzofuranyloxynicotinamide derivatives are novel potent and orally available TGR5 agonists 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2014, 卷号: 82, 页码: 1-15 作者:  Zou, Qingan;  Duan, Hongliang;  Ning, Mengmeng;  Liu, Jia;  Feng, Ying   |  收藏  |  浏览/下载：14/0  |  提交时间：2019/01/08 TGR5  4-Benzofuranyloxynicotinamide  Gallbladder toxicity  Caco-2 permeability   Design, Synthesis, and Structure-Activity Relationships of 3,4,5-Trisubstituted 4,5-Dihydro-1,2,4-oxadiazoles as TGR5 Agonists 期刊论文  OAI收割 CHEMMEDCHEM, 2013, 卷号: 8, 期号: 7, 页码: 1210-1223 作者:  Zhu, Junjie;  Ye, Yangliang;  Ning, Mengmeng;  Mandi, Attila;  Feng, Ying   |  收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08 4  5-dihydro-1  2  4-oxadiazoles  cycloaddition  metabolic disorders  structure-activity relationships  TGR5   Design, Synthesis, and Antidiabetic Activity of 4-Phenoxynicotinamide and 4-Phenoxypyrimidine-5-carboxamide Derivatives as Potent and Orally Efficacious TGR5 Agonists 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2012, 卷号: 55, 期号: 23, 页码: 10475-10489 作者:  Duan, Hongliang;  Ning, Mengmeng;  Chen, Xiaoyan;  Zou, Qingan;  Zhang, Liming   |  收藏  |  浏览/下载：13/0  |  提交时间：2019/01/08 Synthesis and evaluation of piperidine urea derivatives as efficacious 11 beta-hydroxysteroid dehydrogenase type 1 inhibitors in diabetic ob/ob mice 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 8, 页码: 2748-2752 作者:     |  收藏  |  浏览/下载：12/0  |  提交时间：2019/01/08 11 beta-HSD1 inhibitor  Diabetes  Metabolic syndrome  Amide  Urea