中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [25]
采集方式
OAI收割 [25]
内容类型
期刊论文 [25]
发表日期
2019 [1]
2018 [4]
2017 [1]
2015 [1]
2012 [3]
2011 [1]
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学科主题
Pharmacolo... [2]
Chemistry [1]
Immunology [1]
Neuroscien... [1]
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(5R)-5-hydroxytriptolide ameliorates liver lipid accumulation by suppressing lipid synthesis and promoting lipid oxidation in mice
期刊论文
OAI收割
LIFE SCIENCES, 2019, 卷号: 232, 页码: 9
作者:
Dong, Yunxia
;
Lu, Henglei
;
Li, Qiang
;
Qi, Xinming
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
(5R)-5-hydroxytriptolide
NAFLD
Lipid synthesis
Fatty acids oxidation
Fat deposition
CYP3A4 inducer and inhibitor strongly affect the pharmacokinetics of triptolide and its derivative in rats
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 8, 页码: 1386-1392
作者:
Xu, Ye
;
Zhang, Yi-fan
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
triptolide
(5R)-5-hydroxytriptolide
CYP3A4
ritonavir
dexamethasone
pharmacokinetics
immunosuppressant
traditional Chinese medicine
(5R)-5-hydroxytriptolide ameliorates anti-glomerular basement membrane glomerulonephritis in NZW mice by regulating Fc gamma receptor signaling
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 1, 页码: 107-116
作者:
Qi, Qing
;
Li, Heng
;
Lin, Ze-min
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2019/01/08
triptolide
(5R)-5-hydroxytriptolide (LLDT-8)
prednisolone
glomerulonephritis
immune complexes
inflammation
Fc gamma receptor signaling
5r5hydroxytriptolideamelioratesantiglomerularbasementmembraneglomerulonephritisinnzwmicebyregulatingfcyreceptorsignaling
期刊论文
OAI收割
actapharmacologicasinica, 2018, 卷号: 39, 期号: 1, 页码: 107
作者:
Qi Qing
;
Li Heng
;
Lin Zemin
;
Yang Xiaoqian
;
Zhu Fenghua
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
triptolide
(5R)-5-hydroxytriptolide (LLDT-8)
prednisolone
glomerulonephritis
immune complexes
inflammation
Fcy receptor signaling
(5R)-5-hydroxytriptolide ameliorates anti-glomerular basement membrane glomerulonephritis in NZW mice by regulating Fcy receptor signaling
期刊论文
OAI收割
Acta Pharmacologica Sinica, 2018, 卷号: 39, 期号: 1, 页码: 107
作者:
Qi Qing
;
Li Heng
;
Lin Zemin
;
Yang Xiaoqian
;
Zhu Fenghua
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/12/24
triptolide
(5R)-5-hydroxytriptolide (LLDT-8)
prednisolone
glomerulonephritis
immune complexes
inflammation
Fcy receptor signaling
Critical Role of Hepatic Cyp450 sin the Testis-Specific Toxicity of (5R)-5-Hydroxytriptolide in C57BL/6 Mice
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2017, 卷号: 8
作者:
Yu, Cunzhi
;
Li, Yu
;
Liu, Mingxia
;
Gao, Man
;
Li, Chenggang
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2019/01/08
(5R)-5-hydroxytriptolide
functional knockout
cytochrome P450
testes
gamma-H2AX
RNA polymerase II
androgen receptor
(5R)-5-Hydroxytriptolide (LLDT-8) inhibits osteoclastogenesis via RANKL/RANK/OPG signaling pathway
期刊论文
OAI收割
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2015, 卷号: 15
作者:
Shen, Yi
;
Jiang, Ting
;
Wang, Rongsheng
;
He, Shijun
;
Guo, Mengru
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
(5R)-5-Hydroxytriptolide
Osteoclastogenesis
Osteoprotegerin
RANKL
Rheumatoid arthritis
(5R)-5-hydroxytriptolide (LLDT-8), a novel immunosuppressant in clinical trials, exhibits potent antitumor activity via transcription inhibition
期刊论文
OAI收割
CANCER LETTERS, 2012, 卷号: 324, 期号: 1, 页码: 75-82
作者:
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
(5R)-5-hydroxytriptolide
Triptolide
Transcription inhibition
Immunosuppressant discovery from Tripterygium wilfordii Hook f: the novel triptolide analog (5R)-5-hydroxytriptolide (LLDT-8)
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2012, 卷号: 33, 期号: 9, 页码: 1112-1118
作者:
Tang, Wei
;
Zuo, Jian-ping
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
Tripterygium wilfordii Hook f
triptolide
(5R)-5-hydroxytriptolide (LLDT-8)
autoimmune diseases
immunosuppressants
clinical trials
Biotransformation of triptolide to (5R)-5-hydroxytriptolide
期刊论文
OAI收割
Chinese Journal New Drugs, 2012, 卷号: 21, 期号: 3, 页码: 303-309
作者:
Zhao Shunbo
;
Huang Haihua
;
Chen Xiaoyan
;
Li Xiuli
;
Zhong Dafang
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
(5R)-5-hydroxytriptolide
triptolide
microbial transformation
Cunninghamella elegans
HPLC