中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [90]
上海生物化学与细胞... [23]
上海营养与健康研究... [14]
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期刊论文 [197]
学位论文 [7]
会议论文 [1]
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2024 [3]
2023 [8]
2022 [10]
2021 [16]
2020 [5]
2019 [17]
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Immunolog... [15]
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TPN10475 Constrains Effector T Lymphocytes Activation and Attenuates Experimental Autoimmune Encephalomyelitis Pathogenesis by Facilitating TGF-β Signal Transduction
期刊论文
OAI收割
JOURNAL OF NEUROIMMUNE PHARMACOLOGY, 2024, 卷号: 19, 期号: 1, 页码: 16
作者:
Wang, Chun
;
Jiang, Xiangrui
;
Lv, Jie
;
Zhuang, Wei
;
Xie, Ling
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/04/09
Experimental autoimmune encephalomyelitis
TGF-beta signal transduction
Effector CD4(+) T cells activation
Th/Treg
Cell migration
Development of Potent MALT1 Inhibitors Featuring a Novel "2-Thioxo-2,3-dihydrothiazolo[4,5-
d
]pyrimidin-7(6
H
)-one" Scaffold for the Treatment of B Cell Lymphoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2884-2906
作者:
Liang, Xuewu
;
Yu, Haolan
;
Liang, Renwen
;
Feng, Zhuanghui
;
Saidahmatov, Abdusaid
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/04/09
Discovery of a brain-permeable bromodomain and extra terminal domain (BET) inhibitor with selectivity for BD1 for the treatment of multiple sclerosis
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 14
作者:
Chen, Xuetao
;
Wu, Tingting
;
Du, Zhiyan
;
Kang, Wenjing
;
Xu, Rujun
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/02/27
BET
BD1
Bromodomain
Brain-permeable
Multiple sclerosis
Autoimmune diseases: targets, biology, and drug discovery
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12
作者:
Li, Shu-jie
;
Wu, Yan-li
;
Chen, Juan-hua
;
Shen, Shi-yi
;
Duan, Jia
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/01/26
autoimmune disease
autoantigen
immunotherapy
type 1 diabetes
insulin
drug discovery
The aminosteroid U73122 promotes oligodendrocytes generation and myelin formation
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12
作者:
Cui, Shi-hao
;
Suo, Na
;
Yang, Ying
;
Wu, Xuan
;
Guo, Shi-meng
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/12/11
oligodendrocyte
oligodendrocyte progenitor cell
differentiation
remyelination
U73122
Deubiquitylating Enzymes in Cancer and Immunity
期刊论文
OAI收割
ADVANCED SCIENCE, 2023, 页码: 37
作者:
Ren, Jiang
;
Yu, Peng
;
Liu, Sijia
;
Li, Ran
;
Niu, Xin
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/08
cancer
deubiquitylating enzymes (DUBs)
immunity
therapeutic approach
The novel small molecule TPN10518 alleviates EAE pathogenesis by inhibiting AP1 to depress Th1/Th17 cell differentiation
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2023, 卷号: 123, 页码: 12
作者:
Xie, Ling
;
Lv, Jie
;
Saimaier, Kaidireya
;
Han, Sanxing
;
Han, Mengyao
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/10/17
TPN10518
Th1/Th17 cells
AP1
Experimental autoimmune encephalomyelitis
Discovery and Structural Optimization of Covalent ZAP-70 Kinase Inhibitors against Psoriasis
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 15
作者:
Rao, Danni
;
Yang, Tao
;
Feng, Huixu
;
An, Qi
;
Zhang, Shaofeng
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/10/17
Discovery of novel triazine derivatives as potent retinoic acid receptor-related orphan receptor gamma t (ROR gamma t) inverse agonists
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 256, 页码: 18
作者:
Lu, Lixue
;
Chen, Song
;
Yu, Mingcheng
;
Zhou, Ronghui
;
Guo, Siqi
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/10/17
ROR gamma t
Triazines
Inverse agonist
Psoriasis
Autoimmune diseases
ARID3a from the ARID family: structure, role in autoimmune diseases and drug discovery
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12
作者:
Guo, Cheng-cen
;
Xu, H. Eric
;
Ma, Xiong
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/10/17
transcription factors
ARID
ARID3a
autoimmune diseases
systemic lupus erythematosus
primary biliary cholangitis