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The Tyrosine Kinase Inhibitor Bafetinib Inhibits PAR2-induced Activation of TRPV4 In Vitro and Pain In Vivo1
期刊论文
OAI收割
出版物, 2111, 页码: 1-44
作者:
1M S Grace
;
T Lieu
;
B Darby
;
F C Abogadie
;
N Veldhuis N W Bunnett
;
P McIntyre
  |  
收藏
  |  
浏览/下载:271/0
  |  
提交时间:2017/07/24
Transient Receptor Potential Ion Channel
Trpv4
Protease Activated Receptor
Par2
Pain
Tyrosine Kinase
Bafetinib
Discovery of pyrrolo[2,3-d]pyrimidine derivatives as novel FLT3/ IRAK4 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 23
作者:
Yuan, Haibin
;
Gao, Yue
;
Wang, Peipei
;
Dong, Xiaowu
;
Li, Jia
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/08/20
AML
FLT3/IRAK4 inhibitor
Pyrrolo [2,3-d] pyrimidine
Acquired resistance
Adaptive resistance
Discovery of novel imidazo[2,1-b][1,3,4]thiadiazole analogs as fluorescent SHP2 inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 163, 页码: 10
作者:
Zhang, Chun
;
Yan, Xue
;
Gao, Li-Xin
;
Cao, Zi-Tong
;
Cao, Qing
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/08/20
Imidazo[2,1-b][1,3,4]thiadiazole
Inhibitory activities
Fluorescence imaging
Zebrafish
SHP2
Review of CO2 ocean sequestration technology using hydrate method: Feasibility and influencing factors
期刊论文
OAI收割
RENEWABLE & SUSTAINABLE ENERGY REVIEWS, 2025, 卷号: 216, 页码: 13
作者:
Lyu, Huangwu
;
Cheng, Fanbao
;
Dai, Sining
;
Xia, Zhirun
;
Sun, Xiang
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/06/27
CCUS
Ocean sequestration
Sequestration efficiency
CH4-CO2 replacement
Reservoir stability
UBE4B modulates BET inhibitor sensitivity via KLHL22-JAK2-PIM1 axis in hepatocellular carcinoma
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2025, 卷号: 237, 页码: 19
作者:
Wang, Li
;
Huan, Xia-Juan
;
Song, Shan-Shan
;
Bao, Xu-Bin
;
Tian, Chang-Qing
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2025/06/23
UBE4B
BET inhibitors
Resistance
KLHL22
JAK2
Green synthesis of 2-trifluoromethylquinoline skeletons
via
organocatalytic
N
-[(
α
-trifluoromethyl)vinyl]isatins CN bond activation
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2025, 卷号: 36, 期号: 7, 页码: 10
作者:
Ji, Cong-Bin
;
Xie, Ding-Xiong
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2025/07/25
N-[(alpha-Trifluoromethyl)vinyl]isatins
Pfitzinger-type reaction
C-N bond cleavage
2-CF3-quinoline-4-carboxamide
2-CF3-quinoline-4-carboxylicester
Superior properties of biochar contribute to soil carbon sequestration and climate change mitigation
期刊论文
OAI收割
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, 2025, 卷号: 13, 期号: 3, 页码: 12
作者:
He, Debo
;
Yang, Rui
;
Fu, Yan
;
Zhu, Bo
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2025/07/21
Global climate change
Soil greenhouse gas emissions
CO2 emissions reduction
CH4 uptake
DFT calculation
Synthesis, fluorescence properties of novel thiazolo[3,2-b][1,2,4]triazol derivatives as potent SHP2 inhibitors and its uses in sensing for Fe3+and cell imaging
期刊论文
OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2025, 卷号: 1324, 页码: 12
作者:
Yan, Xue
;
Zhang, Chun
;
Gao, Li-Xin
;
Cao, Zi-Tong
;
Gan, Su-Ya
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2025/01/14
Thiazolo[3,2-b][1,2,4]triazole
Salicylic acid
Fe3+ion
Fluorescence property
SHP2
High-capacity and high-stability capacitive desalination with dual redox-active MnCo
2
S
4
/g-C
3
N
4
heterojunction electrode
期刊论文
OAI收割
SEPARATION AND PURIFICATION TECHNOLOGY, 2025, 卷号: 355
作者:
  |  
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2024/11/20
Capacitive desalination
Redox-active electrode
Heterojunction
MnCo2S4
g-C3N4
Design, synthesis and pharmacological evaluation of 1,2,3,4-tetrahydrobenzofuro[2,3-c] pyridine derivatives as p21-activated kinase 4 inhibitors for treatment of pancreatic cancer
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 1, 页码: 438-466
作者:
Li, Yang
;
Fang, Yan
;
Chen, Xiaoyu
;
Tong, Linjiang
;
Feng, Fang
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2025/04/01
P21-activated kinase 4
Tetrahydrobenzofuro[2
3-c]pyridine
Structure-activity relationship
Allosteric inhibitor
Pharmacokinetics properties
Kinase selectivity
Pancreatic cancer
Immune infiltration