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The Tyrosine Kinase Inhibitor Bafetinib Inhibits PAR2-induced Activation of TRPV4 In Vitro and Pain In Vivo1
期刊论文
OAI收割
出版物, 2111, 页码: 1-44
作者:
1M S Grace
;
T Lieu
;
B Darby
;
F C Abogadie
;
N Veldhuis N W Bunnett
;
P McIntyre
  |  
收藏
  |  
浏览/下载:244/0
  |  
提交时间:2017/07/24
Transient Receptor Potential Ion Channel
Trpv4
Protease Activated Receptor
Par2
Pain
Tyrosine Kinase
Bafetinib
Synthesis, fluorescence properties of novel thiazolo[3,2-b][1,2,4]triazol derivatives as potent SHP2 inhibitors and its uses in sensing for Fe3+and cell imaging
期刊论文
OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2025, 卷号: 1324, 页码: 12
作者:
Yan, Xue
;
Zhang, Chun
;
Gao, Li-Xin
;
Cao, Zi-Tong
;
Gan, Su-Ya
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/01/14
Thiazolo[3,2-b][1,2,4]triazole
Salicylic acid
Fe3+ion
Fluorescence property
SHP2
High-capacity and high-stability capacitive desalination with dual redox-active MnCo
2
S
4
/g-C
3
N
4
heterojunction electrode
期刊论文
OAI收割
SEPARATION AND PURIFICATION TECHNOLOGY, 2025, 卷号: 355
作者:
Xu, Yingsheng
;
Quan, Rongxia
;
Zhou, Jianguo
;
Mao, Hengjian
;
Li, Chen
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2024/11/20
Capacitive desalination
Redox-active electrode
Heterojunction
MnCo2S4
g-C3N4
Design, synthesis and pharmacological evaluation of 1,2,3,4-tetrahydrobenzofuro[2,3-c] pyridine derivatives as p21-activated kinase 4 inhibitors for treatment of pancreatic cancer
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 1, 页码: 438-466
作者:
Li, Yang
;
Fang, Yan
;
Chen, Xiaoyu
;
Tong, Linjiang
;
Feng, Fang
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/04/01
P21-activated kinase 4
Tetrahydrobenzofuro[2
3-c]pyridine
Structure-activity relationship
Allosteric inhibitor
Pharmacokinetics properties
Kinase selectivity
Pancreatic cancer
Immune infiltration
Base-driven dehydrohalogenation coupled with catalytic hydrodehalogenation as a novel strategy for rapid dehalogenation of halogenated organic compounds containing aliphatic C-X bonds
期刊论文
OAI收割
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, 2024, 卷号: 12, 期号: 6, 页码: 11
作者:
Qin, Shuting
;
Wu, Chen
;
Ma, Xuanxuan
;
Liu, Sujing
;
Liu, Ying
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/01/10
Halogenated organic compounds (HOCs)
Base
Hydrodehalogenation (HDH)
Dehydrohalogenation (HDX)
Pd/C
(DDT)
1
1-trichloro-2
2-bis(4-chlorophenyl)ethane
Freeze-Thaw Events Change Soil Greenhouse Gas Fluxes Through Modifying Soil Carbon and Nitrogen Cycling Processes in a Temperate Forest in Northeastern China
期刊论文
OAI收割
FORESTS, 2024, 卷号: 15, 期号: 12, 页码: 2082
作者:
Guo, Chuying
;
Zhang, Leiming
;
Li, Shenggong
;
Chen, Yuxin
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/02/24
environmental factors
soil CO2, CH4, and N2O fluxes
freeze-thaw period
growing season
soil depth
Synergistic immune augmentation enabled by covalently conjugating TLR4 and NOD2 agonists
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 278, 页码: 15
作者:
Ding, Dong
;
Gao, Runing
;
Lei, Yujuan
;
Liu, Jianing
;
Zhou, Chengkai
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/10/21
TLR4 agonist
NOD2 agonist
Adjuvant
Covalent conjugation
Subunit vaccine
Discovery of pyrrolo[2,3-d]pyrimidin-4-one derivative YCH3124 as a potent USP7 inhibitor for cancer therapy
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 277, 页码: 17
作者:
Zhuang, Zhen
;
Miao, Yu-Ling
;
Song, Shan-Shan
;
Leng, Guang-Tong
;
Zhang, Xiao-Fei
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/09/26
USP7 inhibitor
Structure-activity relationships
Anti-cancer
pyrrolo[2,3-d]pyrimidin-4-one
A novel 4H-SiC thermal neutron detector based on a metal-oxide-semiconductor structure
期刊论文
OAI收割
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2024, 卷号: 1068
作者:
Meng, Xiang-Dong
;
Han, Yun-Cheng
;
Ren, Lei
;
Zhang, Lian-Xin
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/11/20
4H-SiC
Energy resolution
Thermal neutron detection
Metal-oxide-semiconductor structure
Ni/SiO2/4H-SiC
Microtopography and hydrological regulation alter CO2 and CH4 fluxes in urban wetlands: Evidence from the Pearl River Delta, China
期刊论文
OAI收割
CATENA, 2024, 卷号: 246, 页码: 11
作者:
Ouyang, Kangting
;
Wang, Zhihui
;
Sun, Zhongyu
;
Huang, Guangqing
;
Yang, Long
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2025/04/01
Urban wetlands
Microtopography
Hydrology
Iron oxides
Enzyme activity
CO2 and CH4 flux