中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [48]
心理研究所 [11]
西北高原生物研究所 [4]
昆明植物研究所 [3]
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期刊论文 [73]
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Synthesis and biological evaluation of multimodal monoaminergic arylpiperazine derivatives with potential antidepressant profile
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 275, 页码: 16
作者:
Zheng, Jiefang
;
Zhou, Liping
;
Gong, Xudong
;
Yang, Feipu
;
Cheng, Jiaxin
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/08/22
Triple reuptake inhibitors
5-HT 1A R agonists
Antidepressants
Multimodal serotonergic compounds
The antidepressant-like effect and proposed mechanism of action of TPN672MA, a novel serotonin-dopamine receptor modulator for the treatment of schizophrenia
期刊论文
OAI收割
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2024, 卷号: 242, 页码: 13
作者:
Cheng, Jiaxin
;
Wu, Chunhui
;
Wang, Yu
;
Wang, Zhen
;
He, Yang
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/09/24
TPN672MA
5-HT 1A receptor agonist
D 2 /D 3 receptor partial agonist
5-HT 2A receptor antagonist
Antidepressant-like
Mechanism
Genetic polymorphisms in the 5-HT and endocannabinoid systems moderate the association between childhood trauma and burnout in the general occupational population
期刊论文
OAI收割
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 2024, 卷号: 134, 页码: 10
作者:
Li, Yuling
;
Wang, Lei
;
He, Yingyi
;
Zhu, Shuanggen
;
He, Shu-Chang
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/08/12
Burnout
Serotonin (5-HT)
HTR2A gene
FAAH gene
Childhood trauma
Cannabidiol exhibits anxiolytic-like effects and antipsychotic-like effects in mice models
期刊论文
OAI收割
NEUROSCIENCE LETTERS, 2024, 卷号: 826, 页码: 8
作者:
Shu, Guangzhao
;
He, Yang
;
Suo, Jin
;
Wu, Chunhui
;
Gong, Xudong
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2024/06/27
Cannabidiol
Stress-induced hyperthermia
Phencyclidine-induced negative symptoms of
schizophrenia model
5-HT 1A receptor
Discovery of a CB2 and 5-HT1A receptor dual agonist for the treatment of depression and anxiety
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 20
作者:
Yang, Wenjiao
;
Gong, Xudong
;
Sun, Haiguo
;
Wu, Chunhui
;
Suo, Jin
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/03/06
CB2R agonist
5-HT1AR agonist
CB1R antagonist
Antidepressant
Anxiolytic
New monoamine antidepressant, hypidone hydrochloride (YL-0919), enhances the excitability of medial prefrontal cortex in mice via a neural disinhibition mechanism
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Zhang, Yong-Mei
;
Ye, Lu-Yu
;
Li, Tian-Yu
;
Guo, Fan
;
Guo, Fei
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/01/04
YL-0919
medial prefrontal cortex
GABAergic neurons
5-HT1A receptor
GAD67-GFP transgenic mice
disinhibition
fluoxetine
electrophysiological recording
Synthesis and biological investigation of triazolopyridinone derivatives as potential multireceptor atypical antipsychotics
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 8, 页码: 6
作者:
Shi, Wenqiang
;
Wang, Yu
;
Wu, Chunhui
;
Yang, Feipu
;
Zheng, Wei
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
Triazolopyridinone
Antipsychotic
Multireceptor
5-HT1A receptor
Synthesis and Biological Evaluation of Five-Atom-Linker-Based Arylpiperazine Derivatives with an Atypical Antipsychotic Profile
期刊论文
OAI收割
CHEMMEDCHEM, 2019, 页码: 11
作者:
Wu, Chunhui
;
Wang, Yu
;
Yang, Feipu
;
Shi, Wenqiang
;
Wang, Zhen
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2020/07/01
D-2
5-HT1A
5-HT2A
serotonin
SERT
PCP-induced hyperactivity
Enhancement of Aggression Induced by Isolation Rearing is Associated with a Lack of Central Serotonin
期刊论文
OAI收割
NEUROSCIENCE BULLETIN, 2019, 卷号: 35, 期号: 5, 页码: 841-852
作者:
Liu, Yiqiong
;
Sun, Yunong
;
Zhao, Xiaoyan
;
Kim, Ji-Young
;
Luo, Lu
  |  
收藏
  |  
浏览/下载:88/0
  |  
提交时间:2019/10/31
5-HT
Aggression
Social isolation
Dopamine
Lmx1b
Ligand-induced activation of ERK1/2 signaling by constitutively active G(s)-coupled 5-HT receptors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 9, 页码: 1157-1167
作者:
Liu, Ping
;
Yin, Yu-ling
;
Wang, Ting
;
Hou, Li
;
Wang, Xiao-xi
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
5-HT4R
5-HT6R
5-HT7AR
5-HT
ERK1/2
G(s)
beta-arrestin
Fyn
Src