机构

• 上海药物研究所 [21]
• 金属研究所 [4]
• 上海神经科学研究所 [1]
• 大连化学物理研究所 [1]
• 昆明植物研究所 [1]
• 昆明动物研究所 [1]
• 更多

采集方式

• OAI收割 [29]

内容类型

• 期刊论文 [29]

发表日期

• 2024 [3]
• 2023 [2]
• 2022 [2]
• 2021 [2]
• 2020 [2]
• 2018 [1]
• 更多

学科主题

• Neuroscien... [1]

筛选

浏览/检索结果: 共29条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 The combination of methionine adenosyltransferase 2A inhibitor and methyltransferase like 3 inhibitor promotes apoptosis of non-small cell lung cancer cells and produces synergistic anti-tumor activity 期刊论文  OAI收割 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 卷号: 716, 页码: 12 作者:  Xuan, Yi-Fei;  Lu, Shan;  Ou, Ying-Jie;  Bao, Xu-Bin;  Huan, Xia-Juan   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/07/12 MAT2A inhibitor  METTL3 inhibitor  m6A  Combination therapy  NSCLC   Identification of YCH2823 as a novel USP7 inhibitor for cancer therapy 期刊论文  OAI收割 BIOCHEMICAL PHARMACOLOGY, 2024, 卷号: 222, 页码: 11 作者:  Cheng, Yong -Jun;  Zhuang, Zhen;  Miao, Yu -Ling;  Song, Shan -Shan;  Bao, Xu-Bin   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/05/07 YCH2823  USP7 inhibitor  FT671  BCL6  mTOR inhibitor   Discovery of a 1,6-naphthyridin-4-one-based AXL inhibitor with improved pharmacokinetics and enhanced in vivo antitumor efficacy 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 17 作者:  Lan, Yaohan;  Peng, Xia;  Ji, Yinchun;  Su, Yi;  Duan, Wenhu   |  收藏  |  浏览/下载：30/0  |  提交时间：2024/02/27 AXL inhibitor  In vivo antitumor efficacy  6-Naphthyridin-4-one derivatives  Scaffold hopping  Structure-based drug design   Discovery of novel isopropanolamine inhibitors against MoTPS1 as potential fungicides with unique mechanisms 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 260, 页码: 14 作者:  Jiang, Zhiyang;  Shi, Dongmei;  Chen, Yitong;  Li, Huilin;  Wang, Jin 'e   |  收藏  |  浏览/下载：25/0  |  提交时间：2023/12/08 Rice blast  Trehalose-6-phosphate synthase  Isopropanolamine compounds  Inhibitor  Fungicidal mechanism   化学干预N~6-甲基腺嘌呤修饰的研究进展 期刊论文  OAI收割 高等学校化学学报, 2023, 卷号: 44, 期号: 3 作者:  郇歆宇;  赖淦强;  黄悦;  杨财广   |  收藏  |  浏览/下载：22/0  |  提交时间：2023/07/18 N~6-Methyladenosine modification  Methyltransferase  Demethylase  Small molecule inhibitor  Small molecule agonist  N~6-甲基腺嘌呤修饰  甲基转移酶  去甲基化酶  小分子抑制剂  小分子激动剂   The Multiple Roles of Glucose-6-Phosphate Dehydrogenase in Tumorigenesis and Cancer Chemoresistance 期刊论文  OAI收割 LIFE-BASEL, 2022, 卷号: 12, 期号: 2, 页码: 19 作者:  Song, Jiaqi;  Sun, Huanran;  Zhang, Shuai;  Shan, Changliang   |  收藏  |  浏览/下载：59/0  |  提交时间：2022/06/15 G6PD  tumorigenesis  chemotherapy resistance  inhibitor  metabolism  enzyme   Natural product 1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 2, 页码: 470 作者:  Li Wen;  Liao Liping;  Song Ning;  Liu Yanjun;  Ding Yiluan   |  收藏  |  浏览/下载：20/0  |  提交时间：2023/05/22 glyceraldehyde 3-phosphate dehydrogenase  1  2  3  4  6-penta-O-galloyl-β-D-glucopyranose  hydrogen deuterium exchange mass spectrometry  reversible inhibitor  glycolysis   Acid-activatible micelleplex delivering siRNA-PD-L1 for improved cancer immunotherapy of CDK4/6 inhibition 期刊论文  OAI收割 CHINESE CHEMICAL LETTERS, 2021, 卷号: 32, 期号: 6, 页码: 1929-1936 作者:  Gao, Jing;  Zhang, Hanwu;  Zhou, Fengqi;  Hou, Bo;  Chen, Meiwan   |  收藏  |  浏览/下载：60/0  |  提交时间：2021/08/17 Cancer immunotherapy  siRNA delivery  Acid-activatible micelleplex  CDK4  6 inhibitor  PD-L1 knockdown   Discovery and characterization of a novel glucose-6-phosphate dehydrogenase (G6PD) inhibitor via high-throughput screening 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 40, 页码: 127905 作者:  Luo, Zhongyuan;  Du, Daohai;  Liu, Yanjun;  Lu, Tian;  Liu, Liping   |  收藏  |  浏览/下载：35/0  |  提交时间：2024/03/21 Glucose-6-phosphate dehydrogenase inhibitor  High-throughput screening  Enzyme kinetics assay  Absorption photometry assay   Structural Insight into the Interactions between Structurally Similar Inhibitors and SIRT6 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 卷号: 21, 期号: 7, 页码: 15 作者:  Zhao, Shuang;  Zhu, Yan-Yan;  Wang, Xiao-Yu;  Liu, Yong-Sheng;  Sun, Yun-Xiang   |  收藏  |  浏览/下载：32/0  |  提交时间：2020/07/01 SIRT6  inhibitor  nature molecule  molecular dynamics simulation  scutellarin  hydrophobic interactions  pi-stacking interactions  binding sites