机构

• 上海药物研究所 [3]
• 大连化学物理研究所 [2]
• 化学研究所 [1]
• 武汉病毒研究所 [1]
• 过程工程研究所 [1]
• 中国科学院大学 [1]
• 更多

采集方式

• OAI收割 [9]
• iSwitch采集 [2]

内容类型

• 期刊论文 [11]

发表日期

• 2024 [1]
• 2023 [1]
• 2020 [1]
• 2015 [2]
• 2012 [1]
• 2010 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共11条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Interaction-Based Inductive Bias in Graph Neural Networks: Enhancing Protein-Ligand Binding Affinity Predictions From 3D Structures 期刊论文  OAI收割 IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE, 2024, 卷号: 46, 期号: 12, 页码: 8191-8208 作者:  Yang, Ziduo;  Zhong, Weihe;  Lv, Qiujie;  Dong, Tiejun;  Chen, Guanxing   |  收藏  |  浏览/下载：11/0  |  提交时间：2025/01/14 Proteins  Programmable logic arrays  Three-dimensional displays  Predictive models  Graph neural networks  Data models  Convolution  Protein-ligand binding affinity  graph neural networks  inductive bias  drug-target interaction  structure-based virtual screening   Design, Construction, and Screening of Diversified Pyrimidine-Focused DNA-Encoded Libraries 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 14, 期号: 8, 页码: 1073-1078 作者:  Seydimemet, Mengnisa;  Yang, Yixuan;  Lv, Yuhan;  Liu, Jiaxiang;  Yan, Ziqin   |  收藏  |  浏览/下载：25/0  |  提交时间：2023/10/17 DNA-encoded library technology  Pyrimidine-focusedDNA-encodedlibrary  BRD4  Affinity screening  Inhibitor   A novel thrombin inhibitory peptide discovered from leech using affinity chromatography combined with ultra-high performance liquid chromatography-high resolution mass spectroscopy 期刊论文  OAI收割 JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2020, 卷号: 1151, 页码: 8 作者:  Huang, Qiuyang;  Gao, Qian;  Chai, Xiaoxin;  Ren, Wei;  Zhang, Guifeng   |  收藏  |  浏览/下载：53/0  |  提交时间：2020/07/23 Thrombin  Bioactive Compound Screening  Affinity Chromatography  Uplc-hr-ms  Leech  Thrombin Inhibitory Activity   Affinity purification in target identification: the specificity challenge 期刊论文  OAI收割 archives of pharmacal research, 2015, 卷号: 38, 期号: 9, 页码: 1661-1685 作者:  Zheng, Wenlu;  Li, Gang;  Li, Xiaoyu 收藏  |  浏览/下载：142/0  |  提交时间：2015/11/17 Target identification  Affinity purification  Small molecule  Phenotypic screening  Protein-ligand interaction  Specificity   Multiple ligand detection and affinity measurement by ultrafiltration and mass spectrometry analysis applied to fragment mixture screening 期刊论文  OAI收割 ANALYTICA CHIMICA ACTA, 2015, 卷号: 886, 页码: 98-106 作者:  Qin, Shanshan;  Ren, Yiran;  Fu, Xu;  Shen, Jie;  Chen, Xin 收藏  |  浏览/下载：52/0  |  提交时间：2016/06/23 Ultrafiltration-LC/MS  Multiple ligand detection  Affinity measurement  Fragment library screening  NS5B   Determination of binding constants between one protein and multiple carbohydrates by affinity chromatography on a microchip 期刊论文  OAI收割 journal of chromatography a, 2012, 卷号: 1270, 页码: 340-343 作者:  Liu, Xiaojun;  Wang, Hui;  Liang, Aiye;  Li, Yuling;  Gai, Hongwei 收藏  |  浏览/下载：39/0  |  提交时间：2015/11/12 Binding constants  Carbohydrate-protein interaction  Drug screening  Affinity chromatography  Microchip capillary electrophoresis   Applications of Ultrafiltration Mass Spectrometry in the Studies on Interaction Between Small Drug Molecule and Biological Target 期刊论文  OAI收割 progress in chemistry, 2010, 卷号: 22, 期号: 11, 页码: 2207-2214 Zhou H; Song FR; Liu ZQ; Liu SY 收藏  |  浏览/下载：22/0  |  提交时间：2012/04/25 SCREENING COMBINATORIAL LIBRARIES  PULSED ULTRAFILTRATION  NONCOVALENT COMPLEXES  ESTROGENIC ACTIVITY  ESI-MS  BINDING  AFFINITY  DNA  INHIBITORS  LIGAND   Construction of a high sensitive escherichia coli alkaline phosphatase reporter system for screening affinity peptides 期刊论文  iSwitch采集 Journal of biochemical and biophysical methods, 2007, 卷号: 70, 期号: 3, 页码: 435-439 作者:  Huang, Xu;  Zhang, Xian-En;  Zhou, Ya-Feng;  Zhang, Zhi-Ping;  Cass, Anthony E. G. 收藏  |  浏览/下载：44/0  |  提交时间：2019/05/09 E. coli alkaline phosphatase  Fusion protein  Affinity peptide  Screening system   Screening of inhibitors for influenza A virus using high-performance affinity chromatography and combinatorial peptide libraries 期刊论文  OAI收割 JOURNAL OF CHROMATOGRAPHY A, 2005, 卷号: 1064, 期号: 1, 页码: 59-66 作者:  Zhao, R;  Fang, CL;  Yu, X;  Liu, Y;  Luo, J   |  收藏  |  浏览/下载：27/0  |  提交时间：2019/04/09 High-performance Affinity Chromatography  Combinatorial Peptide Library  Inhibitor  Influenza a Virus  Screening   Screening of inhibitors for influenza a virus using high-performance affinity chromatography and combinatorial peptide libraries 期刊论文  iSwitch采集 Journal of chromatography a, 2005, 卷号: 1064, 期号: 1, 页码: 59-66 作者:  Zhao, R;  Fang, CL;  Yu, X;  Liu, Y;  Luo, J 收藏  |  浏览/下载：25/0  |  提交时间：2019/05/10 High-performance affinity chromatography  Combinatorial peptide library  Inhibitor  Influenza a virus  Screening