中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
上海药物研究所 [111]
过程工程研究所 [27]
大连化学物理研究所 [26]
中国科学院大学 [16]
化学研究所 [12]
西北高原生物研究所 [11]
更多
采集方式
OAI收割 [263]
iSwitch采集 [20]
内容类型
期刊论文 [267]
学位论文 [11]
会议论文 [5]
发表日期
2023 [7]
2022 [11]
2021 [12]
2020 [10]
2019 [14]
2018 [18]
更多
学科主题
Biochemist... [4]
物理化学 [4]
Chemistry,... [2]
Chemistry,... [2]
Science & ... [2]
力学 [2]
更多
筛选
浏览/检索结果:
共283条,第1-10条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
提交时间升序
提交时间降序
发表日期升序
发表日期降序
题名升序
题名降序
作者升序
作者降序
Nanobodies as negative allosteric modulators for human calcium sensing receptor
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 卷号: 695, 页码: 9
作者:
Cui, Qianqian
;
Wang, Lu
;
Wang, Haonan
;
Chen, Xiaochen
;
Han, Li
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/04/09
G-protein-coupled receptor
Extracellular calcium sensing receptor
Nanobody
Cryo-electron microscope
Systemic Ca 2+homoeostasis
The emergence of machine learning force fields in drug design
期刊论文
OAI收割
MEDICINAL RESEARCH REVIEWS, 2024, 页码: 36
作者:
Chen, Mingan
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/02/19
computational chemistry
drug design
force field
machine learning
molecular modeling
Exploring the mechanism of the PTP1B inhibitors by molecular dynamics and experimental study
期刊论文
OAI收割
JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2023, 卷号: 125, 页码: 12
作者:
Zhao, Tian-Tian
;
Hu, Hao-Jie
;
Gao, Li-Xin
;
Zhou, Yu-Bo
;
Zhu, Yun-Long
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
Protein tyrosine phosphatases inhibitors
PTP1B inhibitors
Mechanism study
Molecular dynamics
Structural insights into the interaction of three Y- shaped ligands with PI3Kα
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 34, 页码: 9
作者:
Zhou, Qingtong
;
Liu, Xiao
;
Neri, Dario
;
Li, Wenxin
;
Favalli, Nicholas
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
phosphoinositide 3-kinase
drug target
ligand
binding pocket
chemical scaffold
Fibroblast Activation Protein Targeting Probe with Gly-Pro Sequence for PET of Glioblastoma
期刊论文
OAI收割
MOLECULAR PHARMACEUTICS, 2023, 卷号: 20, 期号: 8, 页码: 4120-4128
作者:
Lai, Chaoquan
;
Cao, Rui
;
Li, Renda
;
He, Chunfeng
;
Wang, Xiao
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/10/17
glioblastoma
fibroblast activation protein
FAPI
PET imaging
Preferred microenvironments of halogen bonds and hydrogen bonds revealed using statistics and QM/MM calculation studies
期刊论文
OAI收割
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2023, 卷号: 25, 期号: 26, 页码: 17692-17699
作者:
Zhou, Liping
;
Li, Jintian
;
Shi, Yulong
;
Wu, Leyun
;
Zhu, Weiliang
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/10/17
Cryo-EM structure of the human chemerin receptor 1-Gi protein complex bound to the C-terminal nonapeptide of chemerin
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 11, 页码: 8
作者:
Wang, Junlin
;
Chen, Geng
;
Liao, Qiwen
;
Lyu, Wenping
;
Liu, Aijun
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/04/09
GPCRs
chemerin
adipokine
innate immunity
cryo-EM
Intercellular Receptor-ligand Binding: Effect of Protein-membrane Interaction
期刊论文
OAI收割
JOURNAL OF MOLECULAR BIOLOGY, 2023, 卷号: 435, 期号: 1, 页码: 17
作者:
Li, Long
;
Ji, Jing
;
Song, Fan
;
Hu, Jinglei
;
Song F(宋凡)
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2023/03/08
Protein-membrane interaction
Intercellular receptor-ligand binding
Membrane fluctuations and curvature
Glycocalyx
Lipid raft
Anxiolytic-like effect of Suanzaoren-Wuweizi herb-pair and evidence for the involvement of the monoaminergic system in mice based on network pharmacology
期刊论文
OAI收割
BMC COMPLEMENTARY MEDICINE AND THERAPIES, 2023, 卷号: 23, 期号: 1, 页码: 17
作者:
Liu, Jie
;
Shi, Jin-Li
;
Guo, Jian-You
;
Chen, Yi
;
Ma, Xiao-Jie
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2023/03/01
Suanzaoren-Wuweizi
Anxiolytic-like effect
Mechanism
Monoaminergic system
Network pharmacology
Detection and analysis of phage M13KO7 using biosensor based on imaging ellipsometry
期刊论文
OAI收割
THIN SOLID FILMS, 2022, 卷号: 763, 页码: 8
作者:
Qi C
;
Zhang YX
;
Lei WJ
;
Jin G(靳刚)
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/12/26
Optical biosensor
Imaging ellipsometry
Microfluidic system
Phage M13KO7
Detection