机构

• 上海药物研究所 [7]
• 海洋研究所 [1]

采集方式

• OAI收割 [8]

内容类型

• 期刊论文 [8]

发表日期

• 2026 [2]
• 2025 [3]
• 2024 [2]
• 2022 [1]

学科主题

筛选

浏览/检索结果: 共8条，第1-8条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择发表日期升序发表日期降序题名升序题名降序提交时间升序提交时间降序作者升序作者降序 Skin-penetrating peptides derived from computational simulation improve transdermal absorption and facilitate topical treatment of melanoma 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2026, 卷号: 16, 期号: 2, 页码: 1140-1154 作者:  Du, Sanjiang;  Wang, Hanlin;  Geng, Feiyang;  Zhang, Zongxu;  Liu, Chenghao   |  收藏  |  浏览/下载：4/0  |  提交时间：2026/04/01 Cell-penetrating peptides  Cutaneous administration  Computational simulation  Melanoma  Floxuridine  AlphaFold  Transdermal drug delivery  Penetratin   Optimizing computational prediction of shrimp-WSSV protein interactions through integration of homology- and topology-based predictions 期刊论文  OAI收割 MOLECULAR GENETICS AND GENOMICS, 2026, 卷号: 301, 期号: 1, 页码: 10 作者:  Yang, Zhanyuan;  Yuan, Jianbo;  Li, Shihao;  Zhang, Xiaojun;  Li, Fuhua   |  收藏  |  浏览/下载：1/0  |  提交时间：2026/06/02 Protein-protein interactions  Penaeid shrimp  STRING interaction  AlphaFold3 modeling  Molecular dynamics simulations   An update for AlphaFold3 versus experimental structures: assessing the precision of small molecule binding in GPCRs 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 10 作者:  Shen, Shi-yi;  Li, Jun-rui;  Wang, Yu-song   |  收藏  |  浏览/下载：2/0  |  提交时间：2025/09/09 GPCR  AlphaFold3  experimental structures  global receptor architecture  orthosteric binding pockets  allosteric modulator  structure-based drug design   Fine structural design of 3βHSD1 inhibitors for prostate cancer 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2025, 卷号: 122, 期号: 26, 页码: 12 作者:  He, Dongyin;  Zhang, Luyao;  Yu, Leiye;  Zhang, Yuhang;  Chen, Jingjing   |  收藏  |  浏览/下载：0/0  |  提交时间：2025/09/09 prostate cancer  drug development  AlphaFold  molecular simulations  3 beta 3HSD1   Strategic Amino Acid Mutations in CPD Cleavage Motif: Impacts on Hydrolysis and C-Terminal Modification Efficiency 期刊论文  OAI收割 CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2025, 卷号: 41, 期号: 3, 页码: 592-600 作者:  Yashinov, Ansor;  Zou, Xiangman;  Hang, Jiayin;  Liu, Zhi;  Song, Fengnan   |  收藏  |  浏览/下载：38/0  |  提交时间：2025/06/23 Protein engineering  C-Terminal modification  Cysteine protease domain  Self-cleavage tag  AlphaFold2   AlphaFold3 versus experimental structures: assessment of the accuracy in ligand-bound G protein-coupled receptors 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2024, 页码: 12 作者:  He, Xin-heng;  Li, Jun-rui;  Shen, Shi-yi;  Xu, H. Eric   |  收藏  |  浏览/下载：52/0  |  提交时间：2025/01/14 AlphaFold  structure-based drug design  artificial intelligence  GPCR  structural biology   FuncPhos-STR: An integrated deep neural network for functional phosphosite prediction based on AlphaFold protein structure and dynamics 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2024, 卷号: 266, 页码: 11 作者:  Zhang, Guangyu;  Zhang, Cai;  Cai, Mingyue;  Luo, Cheng;  Zhu, Fei   |  收藏  |  浏览/下载：88/0  |  提交时间：2024/06/27 Functional phosphosite  Deep learning  AlphaFold protein structure  Dynamics  Protein protein interaction   AlphaFold2 versus experimental structures: evaluation on G protein-coupled receptors 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022, 页码: 7 作者:  He, Xin-heng;  You, Chong-zhao;  Jiang, Hua-liang;  Jiang, Yi;  Xu, H. Eric   |  收藏  |  浏览/下载：61/0  |  提交时间：2022/08/16 G protein-coupled receptors  AlphaFold2  protein structure prediction  drug design  structural biology