中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [7]
南海海洋研究所 [2]
海洋研究所 [2]
昆明植物研究所 [1]
天津工业生物技术研究... [1]
采集方式
OAI收割 [13]
内容类型
期刊论文 [13]
发表日期
2025 [1]
2020 [1]
2019 [2]
2017 [3]
2015 [3]
2013 [1]
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学科主题
Pharmacolo... [2]
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浏览/检索结果:
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Design, synthesis, and evaluation of Menin-targeting compounds for the treatment of acute Myelocytic leukemia (AML)
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17
作者:
Mo, Jun
;
Wang, Yuxian
;
Pan, Youlu
;
Xiao, Qitao
;
Zhao, Jinyi
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2025/08/20
Menin
High binding affinity
Anti-proliferation activity
AML
A new BET inhibitor, 171, inhibits tumor growth through cell proliferation inhibition more than apoptosis induction
期刊论文
OAI收割
INVESTIGATIONAL NEW DRUGS, 2020, 卷号: 38, 期号: 3, 页码: 700-713
作者:
Damaneh, Mohammadali Soleimani
;
Hu, Jian-Ping
;
Huan, Xia-Juan
;
Song, Shan-Shan
;
Tian, Chang-Qing
  |  
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2020/07/01
BET inhibitor
Cell proliferation
Apoptosis
Anti-cancer agent
One Pot and Metal-Free Approach to 3-(2-Hydroxybenzoyl)-1-aza-anthraquinones
期刊论文
OAI收割
MOLECULES, 2019, 卷号: 24, 期号: 16, 页码: 12
作者:
Yuan, Jiaqi
;
He, Qian
;
Song, Shanshan
;
Zhang, Xiaofei
;
Miao, Zehong
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
3-(2-hydroxybenzoyl)-1-aza-anthraquinones
chromones
anti-proliferation agent
Synthesis and Biological Evaluation of Oxopyrido[2,3-d] Pyrimidine-7-ones Derivatives as Covalent L85812/T790M Mutant Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors
期刊论文
OAI收割
LETTERS IN DRUG DESIGN & DISCOVERY, 2019, 卷号: 16, 期号: 8, 页码: 826-834
作者:
Niu, Ao
;
Wang, Yang
;
Yang, Yushe
;
Wei, Jianhai
;
Ding, Jian
  |  
收藏
  |  
浏览/下载:118/0
  |  
提交时间:2020/07/01
Non-small cell lung cancer
irreversible inhibitors
EGFR(T79014)( )mutant
anti-tumor
xenograft model
cell proliferation
Anti-proliferation activity of terpenoids isolated from Euphorbia kansui in human cancer cells and their structure-activity relationship
期刊论文
OAI收割
CHINESE JOURNAL OF NATURAL MEDICINES, 2017, 卷号: 15, 期号: 10, 页码: 766-774
作者:
Hou Jin-Jun
;
Shen Yao
;
Yang Zhou
;
Fang Lin
;
Cai Lu-Ying
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/01/08
Terpenoids
Anti-proliferation activity
Human cancer cells
Structure-activity relationship
Design, synthesis and biological evaluation of thienopyrimidine hydroxamic acid based derivatives as structurally novel histone deacetylase (HDAC) inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 128, 页码: 293-299
作者:
Wang, Jiang
;
Su, Mingbo
;
Li, Tingting
;
Gao, Anhui
;
Yang, Wei
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2019/01/08
HDAC inhibitor
Anti-proliferation
Western blot
Thienopyrimidine
Structure-activity relationship
The B-cell translocation gene 1 (CgBTG1) identified in oyster Crassostrea gigas exhibit multiple functions in immune response
期刊论文
OAI收割
FISH & SHELLFISH IMMUNOLOGY, 2017, 卷号: 61, 页码: 68-78
作者:
Liu, Rui
;
Cheng, Qi
;
Wang, Xiudan
;
Chen, Hao
;
Wang, Weilin
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2017/07/07
B-cell Translocation Gene 1
Crassostrea Gigas
Anti-proliferation
Apoptosis
Immune Response
Pathogen Infection
Identification and functional analysis of a novel IFN-like protein (CgIFNLP) in Crassostrea gigas
期刊论文
OAI收割
FISH & SHELLFISH IMMUNOLOGY, 2015, 卷号: 44, 期号: 2, 页码: 547-554
作者:
Zhang, Ran
;
Liu, Rui
;
Wang, Weilin
;
Xin, Lusheng
;
Wang, Lingling
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2015/07/07
Crassostrea gigas
Interferon
Poly (I: C)
Apoptosis
Phagocytosis
Anti-proliferation
High-Level Expression, Purification and Large-Scale Production of L-Methionine gamma-Lyase from Idiomarina as a Novel Anti-Leukemic Drug
期刊论文
OAI收割
MARINE DRUGS, 2015, 卷号: 13, 期号: 8, 页码: 5492-5507
作者:
Huang, Kui-Ying
;
Hu, Hai-Yan
;
Tang, Yan-Lai
;
Xia, Feng-Geng
;
Luo, Xue-Qun
收藏
  |  
浏览/下载:103/0
  |  
提交时间:2016/11/02
l-Methionine -lyase
purification
production
enzyme
leukemia
anti-leukemic drug
cell proliferation
apoptosis
High-Level Expression, Purification and Large-Scale Production of L-Methionine gamma-Lyase from Idiomarina as a Novel Anti-Leukemic Drug
期刊论文
OAI收割
MARINE DRUGS, 2015, 卷号: 13, 期号: 8, 页码: 5492-5507
作者:
Huang, Kui-Ying
;
Hu, Hai-Yan
;
Tang, Yan-Lai
;
Xia, Feng-Geng
;
Luo, Xue-Qun
收藏
  |  
浏览/下载:103/0
  |  
提交时间:2016/11/02
l-Methionine -lyase
purification
production
enzyme
leukemia
anti-leukemic drug
cell proliferation
apoptosis