机构

• 上海药物研究所 [11]
• 生物物理研究所 [2]
• 上海神经科学研究所 [2]
• 成都生物研究所 [1]
• 大连化学物理研究所 [1]
• 水生生物研究所 [1]
• 更多

采集方式

• OAI收割 [23]

内容类型

• 期刊论文 [23]

发表日期

• 2023 [1]
• 2021 [2]
• 2020 [3]
• 2018 [3]
• 2017 [1]
• 2016 [2]
• 更多

学科主题

• Immunology [3]
• Life Scien... [1]
• Neuroscien... [1]
• Pharmacolo... [1]

筛选

浏览/检索结果: 共23条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Design, synthesis and pharmacological evaluation of 2,3-dihydrobenzo-furan IRAK4 inhibitors for the treatment of diffuse large B-cell lymphoma 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 256, 页码: 16 作者:  Chen, Yun;  Ning, Yi;  Chen, Zhiwei;  Xue, Yaping;  Wu, Qingyun   |  收藏  |  浏览/下载：23/0  |  提交时间：2023/10/17 Apoptosis  Diffuse large B-Cell lymphoma  Interleukin-1 receptor associated kinase 4  Structure-based drug design  2  3-Dihydrobenzofuran   Comprehensive B-Cell Immune Repertoire Analysis of Anti-NMDAR Encephalitis and Anti-LGI1 Encephalitis 期刊论文  OAI收割 FRONTIERS IN IMMUNOLOGY, 2021, 卷号: 12, 页码: 12 作者:  Feng, Jingjing;  Fan, Siyuan;  Sun, Yinwei;  Ren, Haitao;  Guan, Hongzhi   |  收藏  |  浏览/下载：30/0  |  提交时间：2021/11/12 anti-N-methyl-D-aspartate receptor encephalitis  anti-leucine-rich glioma-inactivated 1 encephalitis  B-cell immune repertoire  common clones  adaptive immune responses   Constitutive signal bias mediated by the human GHRHR splice variant 1 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 40, 页码: 10 作者:  Cong, Zhaotong;  Zhou, Fulai;  Zhang, Chao;  Zou, Xinyu;  Zhang, Huibing   |  收藏  |  浏览/下载：71/0  |  提交时间：2021/12/01 class B1 GPCR  receptor bias  cancer  cell proliferation   Design and synthesis of Imidazo[1,2-b]pyridazine IRAK4 inhibitors for the treatment of mutant MYD88 L265P diffuse large B-cell lymphoma 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 190, 页码: 14 作者:  Chen, Yun;  Bai, Gang;  Ning, Yi;  Cai, Shi;  Zhang, Tao   |  收藏  |  浏览/下载：55/0  |  提交时间：2020/07/01 lnterleukin-1 receptor associated kinase 4  Imidazol1,2-6]pyridazine  Diffuse large B-cell lymphoma  Drug design  Antitumor agents   Discovery and biological evaluation of N-(3-(7-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-4-methyl-2-oxo-2H-pyrimido[4,5-d][1,3]oxazin-1(4H)-yl)phenyl)acrylamide as potent Bruton's tyrosine kinase inhibitors 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 415-422 作者:  Lai, Meng-zhen;  Song, Pei-ran;  Dou, Dou;  Diao, Yan-yan;  Tong, Lin-jiang   |  收藏  |  浏览/下载：20/0  |  提交时间：2020/07/01 B cell receptor  Bruton's tyrosine kinase  ibrutinib  small-molecule inhibitor  B cell malignancies   Diffuse large B-cell lymphoma with low F-18-fluorodeoxyglucose avidity features silent B-cell receptor signaling 期刊论文  OAI收割 LEUKEMIA & LYMPHOMA, 2020, 页码: 8 作者:  Sheng, Dong;  Li, Ting;  Wang, Wei-Ge;  Li, Meng-Jiao;  Jiang, Kai-Long   |  收藏  |  浏览/下载：27/0  |  提交时间：2020/07/01 Diffuse large B-cell lymphoma  PET  CT  B-cell receptor signaling  pSYK  GLUT1  HK2   Enhanced interaction between SEC2 mutant and TCR V induces MHC II-independent activation of T cells via PKC/NF-B and IL-2R/STAT5 signaling pathways 期刊论文  OAI收割 JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 51, 页码: 19771-19784 作者:  Fu, Xuanhe;  Xu, Mingkai;  Song, Yubo;  Li, Yongqiang;  Zhang, Huiwen   |  收藏  |  浏览/下载：78/0  |  提交时间：2019/06/04 interleukin  NF-B (NF-KB)  STAT transcription factor  signaling  signal transduction  IL-2  staphylococcal enterotoxin C2  superantigen  T-cell receptor  T-cell activation   Two distinct domains of the glucagon-like peptide-1 receptor control peptide-mediated biased agonism 期刊论文  OAI收割 JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 24, 页码: 9370-9387 作者:  Lei, Saifei;  Clydesdale, Lachlan;  Dai, Antao;  Cai, Xiaoqing;  Feng, Yang   |  收藏  |  浏览/下载：62/0  |  提交时间：2019/01/08 G protein-coupled receptor (GPCR)  glucagon  receptor structure-function  cell signaling  site-directed mutagenesis  biased agonism  GLP-1 receptor  glucagon-like peptide-1  class B peptide hormone  ERK kinase  arrestin  transmembrane domain   Nogo-B receptor promotes epithelial-mesenchymal transition in non-small cell lung cancer cells through the Ras/ERK/Snaill pathway 期刊论文  OAI收割 CANCER LETTERS, 2018, 卷号: 418, 页码: 135-146 作者:  Wu, Donghua;  Zhao, Baofeng;  Qi, Xiaoyu;  Peng, Fang;  Fu, Hailu   |  收藏  |  浏览/下载：43/0  |  提交时间：2019/06/20 Nogo-b Receptor  Non-small Cell Lung Cancer  Epithelial-mesenchymal Transition  Metastasis  Snail1   Dysfunction of PLA2G6 and CYP2C44-associated network signals imminent carcinogenesis from chronic inflammation to hepatocellular carcinoma 期刊论文  OAI收割 JOURNAL OF MOLECULAR CELL BIOLOGY, 2017, 卷号: 9, 期号: 6, 页码: 489-503 作者:  Li, Meiyi;  Li, Chen;  Liu, Wei-Xin;  Liu, Conghui   |  收藏  |  浏览/下载：68/0  |  提交时间：2019/04/28 Cancer-related Inflammation  Activated Receptor-alpha  Induced Liver-injury  C-myc  Integrated Database  Cell-proliferation  Dysplastic Nodules  Edge Biomarkers  Trp Channels  Hepatitis-b