中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
近代物理研究所 [16]
上海药物研究所 [5]
计算技术研究所 [2]
合肥物质科学研究院 [2]
寒区旱区环境与工程研... [1]
中国科学院大学 [1]
更多
采集方式
OAI收割 [27]
iSwitch采集 [2]
内容类型
期刊论文 [24]
会议论文 [4]
学位论文 [1]
发表日期
2024 [1]
2023 [1]
2022 [1]
2021 [1]
2019 [2]
2017 [1]
更多
学科主题
Biochemist... [1]
Cell Biolo... [1]
Oncology [1]
粒子物理与原子核物理 [1]
筛选
浏览/检索结果:
共29条,第1-10条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
题名升序
题名降序
提交时间升序
提交时间降序
作者升序
作者降序
发表日期升序
发表日期降序
Optical Genome Mapping Reveals the Landscape of Structural Variations and Their Clinical Significance in HBOC-Related Breast Cancer
期刊论文
OAI收割
FRONTIERS IN BIOSCIENCE-LANDMARK, 2024, 卷号: 29, 期号: 1, 页码: 1-15
作者:
Cheng, Yanan
;
Dong, Li
;
Bu, Dechao
;
Han, Lei
;
Zhao, Yi
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/05/20
HBOC
breast cancer
optical genome mapping
structural variation
BRCA1/2
chromothripsis
Review: Predictive approaches to breast cancer risk
期刊论文
OAI收割
HELIYON, 2023, 卷号: 9, 期号: 11, 页码: 9
作者:
Huang, Shuai
;
Xu, Jun Tao
;
Yang, Mei
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/05/20
Breast cancer
Risk factors
BRCA1/2
Polygenic risk scores
Artificial intelligence
Design, synthesis and pharmacological evaluation of new PARP1 inhibitors by merging pharmacophores of olaparib and the natural product alantolactone
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 240, 页码: 114574
作者:
Kayumov, Muzaffar
;
Jia, Li
;
Pardaev, Azizbek
;
Song, Shan-Shan
;
Mirzaakhmedov, Sharafitdin
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2024/03/21
PARP1
Olaparib
Alantolactone
Syntheticlethality
BRCA1/2mutant
High chromosome instability identified by low-pass whole-genome sequencing assay is associated with TP53 copy loss and worse prognosis in BRCA1 germline mutation breast cancer
期刊论文
OAI收割
BREAST CANCER, 2021
作者:
Zhu, Liang
;
Pan, Jia-Ni
;
Qian, Ziliang
;
Ye, Wei-Wu
;
Wang, Xiao-Jia
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/09/06
CIN
TP53
BRCA1
LPWGS
Breast cancer
USP9X stabilizes BRCA1 and confers resistance to DNA-damaging agents in human cancer cells
期刊论文
OAI收割
CANCER MEDICINE, 2019, 卷号: 8, 期号: 15, 页码: 6730-6740
作者:
Lu, Qin
;
Zhang, Fang-Lin
;
Lu, Da-Yun
;
Shao, Zhi-Ming
;
Li, Da-Qiang
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
BRCA1
breast cancer
deubiquitinase
PARP inhibitor
USP9X
Prevalence and clinical significance of pathogenic germline BRCA1 2 mutations in Chinese non-small cell lung cancer patients
期刊论文
OAI收割
Cancer Biology & Medicine, 2019, 卷号: 16
作者:
Hu Xingsheng
;
Yang Dongyong
;
Li Yalun
;
Li Li
;
Wang Yan
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2020/12/28
SUSCEPTIBILITY LOCUS
PROSTATE-CANCER
OVARIAN-CANCER
BREAST
RISK
MULTICENTER
EXPRESSION
INHIBITORS
VARIANTS
CARRIERS
Germline BRCA mutations
non-small cell lung cancer
prevalence
BRCA1
BRCA2
Discovery, mechanism and metabolism studies of 2,3-difluorophenyl-linker-containing PARP1 inhibitors with enhanced in vivo efficacy for cancer therapy
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 138, 页码: 514-531
作者:
Chen, Wenhua
;
Guo, Ne
;
Qi, Minghui
;
Dai, Haiying
;
Hong, Minghuang
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/01/08
Antitumor drug
BRCA1/2
PARP inhibitors
Molecular docking
Enhancement of radiosensitivity of MCF-7 breast cancer cells subjected to X-ray or carbon-ion irradiations
期刊论文
iSwitch采集
NUCLEAR SCIENCE AND TECHNIQUES, 2016, 卷号: 27, 期号: 1, 页码: 7
作者:
Xie, Yi
;
Wang, Bing
;
Tanaka, Kaoru
;
Li, Hong-Yan
;
Zhao, Qiu-Yue
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/10/09
Radiosensitivity
Cellular cycle arrest
BRCA1
P21
hTERT
Telomere length
Enhancement of radiosensitivity of MCF-7 breast cancer cells subjected to X-ray or carbon-ion irradiations
期刊论文
OAI收割
NUCLEAR SCIENCE AND TECHNIQUES, 2016, 卷号: 27, 页码: 7
作者:
Xie, Yi
;
Wang, Bing
;
Tanaka, Kaoru
;
Li, Hong-Yan
;
Zhao, Qiu-Yue
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2018/05/31
Radiosensitivity
Cellular cycle arrest
BRCA1
P21
hTERT
Telomere length
BRCA1-Mediated Inflammation and Growth Activated & Inhibited Transition Mechanisms Between No-Tumor Hepatitis/Cirrhotic Tissues and HCC
期刊论文
OAI收割
JOURNAL OF CELLULAR BIOCHEMISTRY, 2014, 卷号: 115, 期号: 4, 页码: 641-650
作者:
Diao, Haizhen
;
Wang, Lin
;
Huang, Juxiang
;
Jiang, Minghu
;
Zhou, Huilei
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
INFLAMMATION
GROWTH
BREAST CANCER 1 EARLY ONSET (BRCA1)
HCC
NO-TUMOR HEPATITIS
CIRRHOTIC TISSUES (HBV OR HCV INFECTION)