机构

• 上海药物研究所 [4]
• 大连化学物理研究所 [3]
• 昆明植物研究所 [1]

采集方式

• OAI收割 [8]

内容类型

• 期刊论文 [8]

发表日期

• 2018 [1]
• 2017 [3]
• 2016 [2]
• 2015 [2]

学科主题

筛选

浏览/检索结果: 共8条，第1-8条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Bavachinin analogues as agonists of pan-peroxisome proliferator-activated receptors 期刊论文  OAI收割 MEDICINAL CHEMISTRY RESEARCH, 2018, 卷号: 27, 期号: 7, 页码: 1851-1862 作者:  Yi, Jingyu;  Du, Guoxin;  Zhao, Yuanyuan;  Zhang, Liuqiang;  Li, Bo   |  收藏  |  浏览/下载：42/0  |  提交时间：2019/01/08 Bavachinin  Metabolic syndrome  PPARs  Reporter gene assaysThese authors contributed equally: Jingyu Yi, Guoxin Du   UGT1A10 Is a High Activity and Important Extrahepatic Enzyme: Why Has Its Role in Intestinal Glucuronidation Been Frequently Underestimated? 期刊论文  OAI收割 MOLECULAR PHARMACEUTICS, 2017, 卷号: 14, 期号: 9, 页码: 2875-2883 作者:  Yang, Ling;  Ge, Guang-Bo;  Jarvinen, Erkka;  Troberg, Johanna;  Finel, Moshe 收藏  |  浏览/下载：23/0  |  提交时间：2017/12/20 UDP-glucuronosyltransferase  recombinant UGT1A10  intestine microsomes  intestinal glucuronidation  estradiol  estrone  morphine  SN-38  AMC  NCHN  bavachinin   UGT1A10 Is a High Activity and Important Extrahepatic Enzyme: Why Has Its Role in Intestinal Glucuronidation Been Frequently Underestimated? 期刊论文  OAI收割 MOLECULAR PHARMACEUTICS, 2017, 卷号: 14, 期号: 9, 页码: 2875-2883 作者:  Troberg, Johanna;  Jarvinen, Erkka;  Ge, Guang-Bo;  Yang, Ling;  Finel, Moshe 收藏  |  浏览/下载：27/0  |  提交时间：2017/12/20 UDP-glucuronosyltransferase  recombinant UGT1A10  intestine microsomes  intestinal glucuronidation  estradiol  estrone  morphine  SN-38  AMC  NCHN  bavachinin   Design, Synthesis, and Structure-Activity Relationships of Bavachinin Analogues as Peroxisome Proliferator-Activated Receptor Agonists 期刊论文  OAI收割 CHEMMEDCHEM, 2017, 卷号: 12, 期号: 2, 页码: 183-193 作者:  Du, Guoxin;  Zhao, Yuanyuan;  Feng, Li;  Yang, Zhuo;  Shi, Jiye   |  收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 bavachinin  diabetes mellitus  PPAR  reporter gene assays  structure-activity relationships   Bavachinin, as a novel natural pan-PPAR agonist, exhibits unique synergistic effects with synthetic PPAR-gamma and PPAR-alpha agonists on carbohydrate and lipid metabolism in db/db and diet-induced obese mice 期刊论文  OAI收割 DIABETOLOGIA, 2016, 卷号: 59, 期号: 6, 页码: 1276-1286 作者:  Feng, Li;  Luo, Huan;  Xu, Zhijian;  Yang, Zhuo;  Du, Guoxin 收藏  |  浏览/下载：27/0  |  提交时间：2016/08/22 Alternative binding site  Bavachinin  Canonical ligand-binding pocket  Carbohydrate metabolism  Lipid metabolism  Pan-PPAR agonist  Synergistic effects   Bavachinin, as a novel natural pan-PPAR agonist, exhibits unique synergistic effects with synthetic PPAR-gamma and PPAR-alpha agonists on carbohydrate and lipid metabolism in db/db and diet-induced obese mice 期刊论文  OAI收割 DIABETOLOGIA, 2016, 卷号: 59, 期号: 6, 页码: 1276-1286 作者:  Feng, Li;  Luo, Huan;  Xu, Zhijian;  Yang, Zhuo;  Du, Guoxin   |  收藏  |  浏览/下载：71/0  |  提交时间：2019/01/08 Alternative binding site  Bavachinin  Canonical ligand-binding pocket  Carbohydrate metabolism  Lipid metabolism  Pan-PPAR agonist  Synergistic effects   Glucuronidation of bavachinin by human tissues and expressed UGT enzymes: Identification of UGT1A1 and UGT1A8 as the major contributing enzymes 期刊论文  OAI收割 drug metabolism and pharmacokinetics, 2015, 卷号: 30, 期号: 5, 页码: 358-365 作者:  Lv, Xia;  Hou, Jie;  Xia, Yang-Liu 收藏  |  浏览/下载：28/0  |  提交时间：2015/11/17 Bavachinin  UDP-glucuronosyltransferases  UGT1A1  UGT1A8  Glucuronidation  Human tissues   Separation and peroxisome proliferator-activated receptor-gamma agonist activity evaluation of synthetic racemic bavachinin enantiomers 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2015, 卷号: 25, 期号: 12, 页码: 2579-2583 作者:  Du, Guoxin;  Feng, Li;  Yang, Zhuo;  Shi, Jiye;  Huang, Cheng   |  收藏  |  浏览/下载：31/0  |  提交时间：2019/01/08 Bavachinin  PPAR-gamma  Supercritical fluid chromatography  Binding assay  Molecular docking