中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
昆明植物研究所 [3]
上海药物研究所 [2]
成都生物研究所 [1]
高能物理研究所 [1]
合肥物质科学研究院 [1]
长春应用化学研究所 [1]
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OAI收割 [9]
iSwitch采集 [1]
内容类型
期刊论文 [10]
发表日期
2023 [1]
2022 [1]
2018 [3]
2016 [1]
2015 [1]
2013 [2]
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学科主题
Applied Mi... [1]
Biotechnol... [1]
Oncology [1]
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Bispecific antibody targeting both B7-H3 and PD-L1 exhibits superior antitumor activities
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 9
作者:
Li, Hua-ying
;
Chen, Yi-li
;
Deng, Xiang-nan
;
Li, Huan-huan
;
Tan, Jie
  |  
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2023/10/17
cancer immunotherapy
B7-H3
PD-L1
bispecific antibodies
VHH
antibody-dependent cell-mediated cytotoxicity (ADCC)
Terpenoids from Nardostachys jatamansi and Their Cytotoxic Activity against Human Pancreatic Cancer Cell Lines
期刊论文
OAI收割
Phytochemistry, 2022, 期号: 200, 页码: 113228
作者:
Li-Mei Ma
;
Kai Wang
;
Xian-Hua Meng
;
Yi-Dan Zheng
;
Cheng-Bo Wang
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2022/11/30
Nardostachys jatamansi DC.
Valerianaceae
Terpenoids
Cytotoxicity
Human pancreatic cancer cell lines
Efficacy of green nanoparticles against cancerous and normal cell lines: a systematic review and meta-analysis
期刊论文
iSwitch采集
Iet nanobiotechnology, 2018, 卷号: 12, 期号: 4, 页码: 377-391
作者:
Barabadi, Hamed
;
Alizadeh, Ahad
;
Ovais, Muhammad
;
Ahmadi, Amirhossein
;
Shinwari, Zabta Khan
收藏
  |  
浏览/下载:76/0
  |  
提交时间:2019/04/23
Reviews
Nanoparticles
Cancer
Nanomedicine
Magnetic particles
Nanomagnetics
Nanofabrication
Cellular biophysics
Bayes methods
Microorganisms
Toxicology
Antibacterial activity
Green nanoparticles
Cancerous cell lines
Normal cell lines
Review
Meta-analysis
Microbial synthesised metallic nanoparticles
Bayesian generalised linear model
Hela cancer cell lines
A549 cancer cell lines
Gram-negative bacteria
Gram-positive bacteria
Cytotoxicity
Anticancer agents
Cancer disease treatment
targetingthepi3kaktmtorsignalingpathwaybypterostilbeneattenuatesmantlecelllymphomaprogression
期刊论文
OAI收割
actabiochimicaetbiophysicasinica, 2018, 卷号: 50, 期号: 8, 页码: 782
作者:
Yu Dandan
;
Zhang Yong
;
Chen Gege
;
Xie Yongsheng
;
Xu Zhijian
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/07/01
PROTEIN-KINASE PATHWAY
CANCER IN-VITRO
TRANSDUCTION PATHWAYS
CYCLE ARREST
APOPTOSIS
ACTIVATION
PATHOGENESIS
INHIBITION
ANTICANCER
EXPRESSION
mantle cell lymphoma
pterostilbene
antiproliferative activity
PI3K/Akt/mTOR pathway
synergistic cytotoxicity
Synthesis and inhibitory effect of 10-chlorocanthin-6-one on ovarian cancer HO8910PM cells
期刊论文
OAI收割
BIOTECHNOLOGY LETTERS, 2018, 卷号: 40, 期号: 1, 页码: 23-30
作者:
Li, Wenhua
;
Chen, Yuwen
;
Sheng, Yuwen
;
Xie, Zeyu
;
Tang, Yaxiong
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/12/24
Bim
Cell apoptosis
10-Chlorocanthin-6-one
Cytotoxicity
Ovarian cancer cell line
Novel cytotoxic benzophenones from Garcinia paucinervis identified by UPLC-QTOF-MSE
期刊论文
OAI收割
PLANTA MEDICA, 2016, 卷号: 82, 页码: 1
作者:
Li, P.
;
Senthilkumar, H. Anandhi
;
Figueroa, M.
;
Wu, S. B.
;
Fata, J. E.
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2017/12/11
Uplc-qtof-mse
Novel Benzophenones
Garcinia Paucinervis
Cytotoxicity
Breast Cancer Cell Lines
The formation of intracellular nanoparticles correlates with cisplatin resistance
期刊论文
OAI收割
SCIENCE CHINA-MATERIALS, 2015, 卷号: 58
-
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/10/26
GLUTATHIONE-S-TRANSFERASE
SQUAMOUS-CELL CARCINOMA
LOCALLY ADVANCED HEAD
PLATINUM NANOPARTICLES
NECK-CANCER
MOLECULAR-MECHANISMS
DRUG-RESISTANCE
CHEMOTHERAPY
CYTOTOXICITY
NANOMATERIALS
Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells
期刊论文
OAI收割
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:
Zeng, Guang-Zhi
;
Fan, Jun-Ting
;
Xu, Jun-Ju
;
Li, Yan
;
Tan, Ning-Hua
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2015/05/14
2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone (MTA)
one of the major components isolated from the traditional
Chinese medicine Rubia yunnanensis
exhibited inhibitory activity on the proliferation of several
human cancer cell lines. The results from an annexin V-FITC (fluoresein-5-isothiocyanate) apoptosis assay
and DNA content analysis showed that MTA exerted cytotoxicity via apoptosis induction and G2/M cell cycle
arrest in human cervical carcinoma HeLa cells. Further
MTA was found to induce apoptosis of HeLa cells
through the mitochondria-mediated pathway. It caused the translocation of Bax to the mitochondria and
release of cytochrome c into the cytosol
which caused the cleavage of caspase and poly(ADP-ribose)
polymerase and finally triggered the apoptosis. Furthermore
the p53/p21/Cdc2-cyclin B1 signaling was
found related to the G2/M arrest caused by MTA. The over-expression of p21 and down-expression of
cyclin B1 caused by MTA inactivated the Cdc2-cyclin B1 complex of G2/M checkpoint and finally caused
the G2/M arrest in HeLa cells. This study demonstrated that MTA is a potential anti-cancer component of
R. yunnanensis
a folk anti-cancer herb used in Yunnan
China.
Stereospecific intra-molecular interligand interactions affecting base-specific metal bonding to purine nucleobases in the solid state
期刊论文
OAI收割
coordination chemistry reviews, 2013, 卷号: 257, 期号: 19-20, 页码: 2198-2813
Aoki K
;
Fujisawa I
;
Murayama K
;
Hu NH
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2014/04/15
X-RAY CRYSTAL
RUTHENIUM(II) ARENE COMPLEXES
NUCLEIC-ACID BASES
CANCER-CELL CYTOTOXICITY
TREN LIGAND-SYSTEM
PT-II ENTITIES
MOLECULAR-STRUCTURE
STRUCTURAL-CHARACTERIZATION
CROSS-LINK
MODEL NUCLEOBASES
Prediction of broad spectrum resistance of tumors towards anticancer drugs
期刊论文
OAI收割
CLINICAL CANCER RESEARCH, 2008, 卷号: 14, 期号: 8, 页码: 2405-2412
Efferth, Thomas
;
Konkimalla, V. Badireenath
;
Wang, Yi-Fen
;
Sauerbrey, Axel
;
Meinhardt, Silke
;
Zintl, Felix
;
Mattern, Juegen
;
Volm, Manfred
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2012/10/12
TRADITIONAL CHINESE MEDICINE
CASSETTE TRANSPORTER GENES
SHORT-TERM TEST
MULTIDRUG-RESISTANCE
CELL-LINES
CANCER-CHEMOTHERAPY
TETRAZOLIUM ASSAY
SENSITIVITY
LEUKEMIA
CYTOTOXICITY