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Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共10条,第1-10条 帮助

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Bispecific antibody targeting both B7-H3 and PD-L1 exhibits superior antitumor activities 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 9
作者:  
Li, Hua-ying;  Chen, Yi-li;  Deng, Xiang-nan;  Li, Huan-huan;  Tan, Jie
  |  收藏  |  浏览/下载:56/0  |  提交时间:2023/10/17
Terpenoids from Nardostachys jatamansi and Their Cytotoxic Activity against Human Pancreatic Cancer Cell Lines 期刊论文  OAI收割
Phytochemistry, 2022, 期号: 200, 页码: 113228
作者:  
Li-Mei Ma;  Kai Wang;  Xian-Hua Meng;  Yi-Dan Zheng;  Cheng-Bo Wang
  |  收藏  |  浏览/下载:41/0  |  提交时间:2022/11/30
Efficacy of green nanoparticles against cancerous and normal cell lines: a systematic review and meta-analysis 期刊论文  iSwitch采集
Iet nanobiotechnology, 2018, 卷号: 12, 期号: 4, 页码: 377-391
作者:  
Barabadi, Hamed;  Alizadeh, Ahad;  Ovais, Muhammad;  Ahmadi, Amirhossein;  Shinwari, Zabta Khan
收藏  |  浏览/下载:76/0  |  提交时间:2019/04/23
targetingthepi3kaktmtorsignalingpathwaybypterostilbeneattenuatesmantlecelllymphomaprogression 期刊论文  OAI收割
actabiochimicaetbiophysicasinica, 2018, 卷号: 50, 期号: 8, 页码: 782
作者:  
Yu Dandan;  Zhang Yong;  Chen Gege;  Xie Yongsheng;  Xu Zhijian
  |  收藏  |  浏览/下载:32/0  |  提交时间:2020/07/01
Synthesis and inhibitory effect of 10-chlorocanthin-6-one on ovarian cancer HO8910PM cells 期刊论文  OAI收割
BIOTECHNOLOGY LETTERS, 2018, 卷号: 40, 期号: 1, 页码: 23-30
作者:  
Li, Wenhua;  Chen, Yuwen;  Sheng, Yuwen;  Xie, Zeyu;  Tang, Yaxiong
  |  收藏  |  浏览/下载:24/0  |  提交时间:2020/12/24
Novel cytotoxic benzophenones from Garcinia paucinervis identified by UPLC-QTOF-MSE 期刊论文  OAI收割
PLANTA MEDICA, 2016, 卷号: 82, 页码: 1
作者:  
Li, P.;  Senthilkumar, H. Anandhi;  Figueroa, M.;  Wu, S. B.;  Fata, J. E.
  |  收藏  |  浏览/下载:25/0  |  提交时间:2017/12/11
The formation of intracellular nanoparticles correlates with cisplatin resistance 期刊论文  OAI收割
SCIENCE CHINA-MATERIALS, 2015, 卷号: 58
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  |  收藏  |  浏览/下载:15/0  |  提交时间:2020/10/26
Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文  OAI收割
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:  
Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju;  Li, Yan;  Tan, Ning-Hua
收藏  |  浏览/下载:47/0  |  提交时间:2015/05/14
2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone (MTA)  one of the major components isolated from the traditional  Chinese medicine Rubia yunnanensis  exhibited inhibitory activity on the proliferation of several  human cancer cell lines. The results from an annexin V-FITC (fluoresein-5-isothiocyanate) apoptosis assay  and DNA content analysis showed that MTA exerted cytotoxicity via apoptosis induction and G2/M cell cycle  arrest in human cervical carcinoma HeLa cells. Further  MTA was found to induce apoptosis of HeLa cells  through the mitochondria-mediated pathway. It caused the translocation of Bax to the mitochondria and  release of cytochrome c into the cytosol  which caused the cleavage of caspase and poly(ADP-ribose)  polymerase and finally triggered the apoptosis. Furthermore  the p53/p21/Cdc2-cyclin B1 signaling was  found related to the G2/M arrest caused by MTA. The over-expression of p21 and down-expression of  cyclin B1 caused by MTA inactivated the Cdc2-cyclin B1 complex of G2/M checkpoint and finally caused  the G2/M arrest in HeLa cells. This study demonstrated that MTA is a potential anti-cancer component of  R. yunnanensis  a folk anti-cancer herb used in Yunnan  China.  
Stereospecific intra-molecular interligand interactions affecting base-specific metal bonding to purine nucleobases in the solid state 期刊论文  OAI收割
coordination chemistry reviews, 2013, 卷号: 257, 期号: 19-20, 页码: 2198-2813
Aoki K; Fujisawa I; Murayama K; Hu NH
收藏  |  浏览/下载:29/0  |  提交时间:2014/04/15
Prediction of broad spectrum resistance of tumors towards anticancer drugs 期刊论文  OAI收割
CLINICAL CANCER RESEARCH, 2008, 卷号: 14, 期号: 8, 页码: 2405-2412
Efferth, Thomas; Konkimalla, V. Badireenath; Wang, Yi-Fen; Sauerbrey, Axel; Meinhardt, Silke; Zintl, Felix; Mattern, Juegen; Volm, Manfred
收藏  |  浏览/下载:29/0  |  提交时间:2012/10/12