中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [4]
金属研究所 [1]
昆明植物研究所 [1]
长春应用化学研究所 [1]
近代物理研究所 [1]
采集方式
OAI收割 [8]
内容类型
期刊论文 [8]
发表日期
2022 [1]
2020 [3]
2013 [1]
2006 [3]
学科主题
Biochemist... [1]
Chemistry [1]
Pharmacolo... [1]
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Chemical constituents from the flowers of Hypericum monogynum L. with COX-2 inhibitory activity
期刊论文
OAI收割
PHYTOCHEMISTRY, 2022, 卷号: 193, 页码: 112970
作者:
Li,Ya-Nan
;
Zeng,Yan-Rong
;
Yang,Jue
;
He,Wenwen
;
Chen,Junlei
  |  
收藏
  |  
浏览/下载:103/0
  |  
提交时间:2022/04/02
Hypericum monogynum L.
Hypericaceae
Chemical constituents
Polycyclic polyprenylated acylphloroglucinols
Flavonoids
COX-2 inhibitors
Novel Carborane Compounds Based on Cyclooxygenase-2 Inhibitors for Effective Boron Neutron Capture Therapy of Tongue Squamous Cell Carcinoma
期刊论文
OAI收割
CHEMISTRYSELECT, 2020, 卷号: 5, 期号: 46, 页码: 14652-14660
作者:
Zhang, Taofeng
;
Du, Shaobo
;
Wang, Yu
;
Guo, Yanzhu
;
Yi, Yangman
  |  
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2021/12/13
Boron neutron capture therapy
Tongue squamous cell carcinoma
COX-2 inhibitors
Biological activity
Growth factors
Novel mutations in BRCA2 intron 11 and overexpression of COX-2 and BIRC3 mediate cellular resistance to PARP inhibitors
期刊论文
OAI收割
AMERICAN JOURNAL OF CANCER RESEARCH, 2020, 卷号: 10, 期号: 9, 页码: 2813-+
作者:
Chen, Hua-Dong
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/12/24
PARP inhibitors resistance
BRCA2
COX-2
BIRC3
apoptotic resistance
Novel mutations in BRCA2 intron 11 and overexpression of COX-2 and BIRC3 mediate cellular resistance to PARP inhibitors
期刊论文
OAI收割
AMERICAN JOURNAL OF CANCER RESEARCH, 2020, 卷号: 10, 期号: 9, 页码: 2813-+
作者:
Chen, Hua-Dong
;
Guo, Ne
;
Song, Shan-Shan
;
Chen, Chuan-Huizi
;
Miao, Ze-Hong
  |  
收藏
  |  
浏览/下载:104/0
  |  
提交时间:2020/12/24
PARP inhibitors resistance
BRCA2
COX-2
BIRC3
apoptotic resistance
Bioactivity fingerprint analysis of cyclooxygenase-2 ligands from radix Aconiti by ultrafiltration-UPLC-MSn
期刊论文
OAI收割
analytical and bioanalytical chemistry, 2013, 卷号: 405, 期号: 23, 页码: 7437-7445
Zhu HB
;
Liu S
;
Li X
;
Song FR
;
Liu ZQ
;
Liu SY
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2014/04/15
TRANSFORM MASS-SPECTROMETRY
INHIBITORS
CHROMATOGRAPHY
ALKALOIDS
PRODUCTS
QUALITY
ACETYLCHOLINESTERASE
MEDICINES
COX-2
HPLC
Essential structural profile of a dual functional inhibitor against cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX): Molecular docking and 3D-QSAR analyses on DHDMBF analogues
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2006, 卷号: 14, 期号: 10, 页码: 3428-3437
作者:
Zheng, MY
;
Zhang, ZS
;
Zhu, WL
;
Liu, H
;
Luo, XM
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
COX-2
5-LOX
dual inhibitors NSAIDs
DHDMBF
homology modeling
docking
3D-QSAR
CoMFA
CoMSIA
Role of rat liver cytochrome P450 3A and 2D in metabolism of imrecoxib
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2006, 卷号: 27, 期号: 3, 页码: 372-380
作者:
Xu HY
;
Xie ZY
;
Zhang P
;
Sun J
;
Chu FM
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/02/02
NONSTEROIDAL ANTIINFLAMMATORY DRUGS
COX-2 INHIBITORS
IN-VITRO
MICROSOMES
CYCLOOXYGENASE-2
OSTEOARTHRITIS
ISOENZYMES
NSAIDS
VIVO
imrecoxib
cytochrome P450
metabolism
liver microsomes