中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [37]
武汉病毒研究所 [3]
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期刊论文 [49]
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Molecular basis for ligand recognition and receptor activation of the prostaglandin D2 receptor DP1
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2025, 卷号: 122, 期号: 22, 页码: 11
作者:
Xu, Jiuyin
;
Wu, Yanli
;
Xu, Youwei
;
Li, Yang
;
He, Xinheng
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
prostaglandin D2 receptor 1
receptor activation
drug design
An efficient deep learning-based strategy to screen inhibitors for GluN1/GluN3A receptor
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 9
作者:
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/04/24
deep learning
scoring function
GluN1/GluN3A receptor
N
-methyl-
D
-aspartate (NMDA) receptor
virtual screening
drug discovery
The antidepressant-like effect and proposed mechanism of action of TPN672MA, a novel serotonin-dopamine receptor modulator for the treatment of schizophrenia
期刊论文
OAI收割
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2024, 卷号: 242, 页码: 13
作者:
Cheng, Jiaxin
;
Wu, Chunhui
;
Wang, Yu
;
Wang, Zhen
;
He, Yang
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2024/09/24
TPN672MA
5-HT 1A receptor agonist
D 2 /D 3 receptor partial agonist
5-HT 2A receptor antagonist
Antidepressant-like
Mechanism
Comprehensive B-Cell Immune Repertoire Analysis of Anti-NMDAR Encephalitis and Anti-LGI1 Encephalitis
期刊论文
OAI收割
FRONTIERS IN IMMUNOLOGY, 2021, 卷号: 12, 页码: 12
作者:
Feng, Jingjing
;
Fan, Siyuan
;
Sun, Yinwei
;
Ren, Haitao
;
Guan, Hongzhi
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/11/12
anti-N-methyl-D-aspartate receptor encephalitis
anti-leucine-rich glioma-inactivated 1 encephalitis
B-cell immune repertoire
common clones
adaptive immune responses
Recent advances in dopaminergic strategies for the treatment of Parkinson's disease
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:
Mao, Qi
;
Qin, Wang-zhi
;
Zhang, Ao
;
Ye, Na
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2020/07/01
Parkinson's disease
dopamine
D-1 receptor
D-2 receptor
allosteric modulator
neuroprotection
multitarget
drug discovery and development
neurodegenerative diseases
designsynthesisandbiologicalevaluationofnoveltetrahydroprotoberberinederivativesthpbsasproproteinconvertasesubtilisinkexintype9pcsk9modulatorsforthetreatmentofhyperlipidemia
期刊论文
OAI收割
actapharmaceuticasinicab, 2019, 卷号: 9, 期号: 6, 页码: 1216
作者:
Wu Chenglin
;
Xi Cong
;
Tong Junhua
;
Zhao Jing
;
Jiang Hualiang
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
DOPAMINE D-1
BERBERINE
EXPRESSION
INHIBITORS
IDENTIFICATION
CHOLESTEROL
MUTATIONS
LDLR
PCSK9
Tetrahydroprotoberberine derivatives
Low-density lipoprotein cholesterol
Lipid-lowering
PCSK9 expression
Low-density lipoprotein receptor
Total cholesterol
Hyperlipidemia hamster
Identification of Alkaloids from Corydalis yanhusuo W. T. Wang as Dopamine D-1 Receptor Antagonists by Using CRE-Luciferase Reporter Gene Assay
期刊论文
OAI收割
MOLECULES, 2018, 卷号: 23, 期号: 10, 页码: 10
作者:
Wu, Lehao
;
Zhang, Weiyue
;
Qiu, Xin
;
Wang, Chaoran
;
Liu, Yanfang
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2019/06/20
Corydalis yanhusuoW. T. Wang
luciferase reporter gene assay
D-1 receptor
FLIPR
Identification of alkaloids from corydalis yanhusuo w. t. wang as dopamine d-1 receptor antagonists by using cre-luciferase reporter gene assay
期刊论文
iSwitch采集
Molecules, 2018, 卷号: 23, 期号: 10, 页码: 10
作者:
Wu, Lehao
;
Zhang, Weiyue
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2019/05/08
Corydalis yanhusuow. t. wang
Luciferase reporter gene assay
D-1 receptor
Flipr
GLYX-13 Ameliorates Schizophrenia-Like Phenotype Induced by MK-801 in Mice: Role of Hippocampal NR2B and DISC1
期刊论文
OAI收割
FRONTIERS IN MOLECULAR NEUROSCIENCE, 2018, 卷号: 11
作者:
Zhou, Dongsheng
;
Lv, Dan
;
Wang, Zhen
;
Zhang, Yanhua
;
Chen, Zhongming
  |  
收藏
  |  
浏览/下载:96/0
  |  
提交时间:2019/01/08
GLYX-13
disrupted-in-schizophrenia 1
N-methyl-D-aspartate receptor
N-methyl D-aspartate receptor subtype 2B
schizophrenia
Distinct roles of dopamine receptors in the lateral thalamus in a rat model of decisional impulsivity
期刊论文
iSwitch采集
Neuroscience bulletin, 2017, 卷号: 33, 期号: 4, 页码: 413-422
作者:
Wang, Zhiyan
;
Liang, Shengxiang
;
Yu, Shuangshuang
;
Xie, Tong
;
Wang, Baicheng
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2019/04/23
Lateral thalamus
Decisional impulsivity
D1 receptor
D2 receptor