中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [64]
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期刊论文 [276]
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Applying natural product repurposing strategy to identify baicalein as novel caseinolytic protease P inhibitor and its application in the treatment of rice bacterial diseases
期刊论文
OAI收割
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 2025, 卷号: 214, 页码: 12
作者:
Sun, Zhaoju
;
Yang, Teng
;
Long, Zhouqing
;
Fu, Xichun
;
Meng, Jiao
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/12/04
Plant bacterial diseases
ClpP inhibitor
Natural products
Baicalein
Rice
Engineering small-molecule phototheranostics for infectious disease imaging and therapy in NIR-II
期刊论文
OAI收割
TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2025, 卷号: 192, 页码: 27
作者:
Ding, Qihang
;
Zhang, Yifan
;
Fan, Xianrun
;
Zhu, Liming
;
Han, Linli
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/12/04
Infectious diseases
NIR-II
Molecular imaging
Phototheranostics
Small molecules
Recent progress in histone post-translational modifications as regulators of metabolic diseases: A review
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2025, 卷号: 330, 页码: 23
作者:
Zhu, Aiqiang
;
Ye, Tong
;
Tan, Minjia
;
Xu, Jun-Yu
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/12/04
PTMs
Metabolic diseases
Epigenetics
Detection methods
Pharmacological interventions
Solutions and challenges in AI-based pest and disease recognition
期刊论文
OAI收割
COMPUTERS AND ELECTRONICS IN AGRICULTURE, 2025, 卷号: 238, 页码: 22
作者:
Liu, Xinda
;
Zhang, Qinyu
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/12/03
Agricultural practices
Crop diseases and pets
Deep learning
Few-shot learning
Network architectures
Lightweight models
Hardware
SSC-PPI: A Subspace Structure Consistency-Based Method for Protein-Protein Interactions Prediction
期刊论文
OAI收割
IEEE TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2025, 卷号: 22, 期号: 6, 页码: 2477-2490
作者:
Ma, Ziping
;
Min, Weiqing
;
Zhang, Huanpu
;
Huang, Yulei
;
Jiang, Shuqiang
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2026/05/25
Proteins
Feature extraction
Drugs
Diseases
Amino acids
Accuracy
Predictive models
Dimensionality reduction
Data mining
Databases
Protein-protein interactions
dimension reduction
unsupervised feature selection
latent representation learning
Discovery of indole derivatives as STING degraders
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 294, 页码: 21
作者:
An, Yuxiang
;
Zhang, Yan
;
Luo, Xin
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2025/08/20
Autoimmune diseases
Degrader
Inflammatory
PROTAC
STING
Immunosuppressive nitrogen-containing triterpenoid saponins from
Mussaenda
erosa
and the therapeutic efficacy of heinsiagenin A in a murine lupus erythematosus model
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 163, 页码: 11
作者:
Xu, Yidan
;
Xiang, Mai
;
Chang, Yuan
;
Chen, Zhenhua
;
Zhang, Rujun
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2025/08/20
Mussaenda erosa
Nitrogen-containing triterpenoid saponins
Immunosuppressive activity
Autoimmune diseases
Heinsiagenin A
Ultrasensitive magnetic nanomechanical biosensors for simultaneous detection of multiple cardiovascular disease biomarkers in a single blood drop
期刊论文
OAI收割
BIOSENSORS & BIOELECTRONICS, 2025, 卷号: 280, 页码: 10
作者:
Chen, Qiubo
;
Zhang, Lin
;
Qiao, Zihan
;
Yang, Yipeng
;
Wu, Wenjie
  |  
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2025/06/23
Cardiovascular diseases (CVD)
Early diagnosis
Ultrasensitive sensor
Magnetic force
Microcantilever array
A drop of blood
Nanomechanics
Discovery of novel Bis-amide analogue ST12 for the treatment of inflammatory bowel diseases (IBD) by inhibiting NLRP3 inflammasome activation
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 159, 页码: 14
作者:
Sun, Zhiqiang
;
Zang, Qinru
;
Xu, Chenglong
;
Zhang, Xuewen
;
Kang, Zhenghui
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2025/05/27
Anti-inflammatory agents
Nitric oxide (NO)
NLRP3 inflammasome
Inflammatory bowel diseases (IBD)
Molecular imaging-guided diagnosis and treatment integration for brain diseases
期刊论文
OAI收割
BIOMATERIALS, 2025, 卷号: 316, 页码: 19
作者:
Yu, Donghu
;
Liu, Menghao
;
Ding, Qihang
;
Wu, Youxian
;
Wang, Tianqing
  |  
收藏
  |  
浏览/下载:94/0
  |  
提交时间:2025/04/01
Molecular imaging
Integration of diagnosis and treatment
Brain diseases