中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [6]
过程工程研究所 [1]
长春应用化学研究所 [1]
采集方式
OAI收割 [8]
内容类型
期刊论文 [8]
发表日期
2019 [1]
2014 [1]
2013 [3]
2012 [1]
2009 [2]
学科主题
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Supersaturated polymeric micelles for oral silybin delivery: the role of the Soluplus-PVPVA complex
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 1, 页码: 107-117
作者:
Zhu, Chunliu
;
Gong, Shuang
;
Ding, Jinsong
;
Yu, Miaorong
;
Ahmad, Ejaj
  |  
收藏
  |  
浏览/下载:106/0
  |  
提交时间:2020/07/01
Silybin
Soluplus
PVPVA
Complex
Supersaturated drug delivery system
Oral bioavailability
effectsofanal3andmg2containingantacidferroussulfateandcalciumcarbonateontheabsorptionofnemonoxacintg873870inhealthychinesevolunteers
期刊论文
OAI收割
actapharmacologicasinica, 2014, 卷号: 35, 期号: 12, 页码: 1586
作者:
Zhang Yifan
;
Dai Xiaojian
;
Wang Ting
;
Chen Xiaoyan
;
Li Liang
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/07/01
NON-FLUORINATED QUINOLONE
CIPROFLOXACIN
GATIFLOXACIN
PHARMACOKINETICS
BIOAVAILABILITY
ALUMINUM
SAFETY
SLEEP
nemonoxacin
nonfluorinated quinolone
drug-drug interaction
antacid
ferrous sulfate
calcium carbonate
drug absorption
clinical pharmacokinetics
Novel pH-sensitive lipid-polymer composite microspheres of 10-hydroxycamptothecin exhibiting colon-specific biodistribution and reduced systemic absorption
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL SCIENCES, 2013, 卷号: 102, 期号: 6, 页码: 1752-1759
作者:
Gan, Li
;
Gao, Yi-Ping
;
Zhu, Chun-Liu
;
Zhang, Xin-Xin
;
Gan, Yong
  |  
收藏
  |  
浏览/下载:92/0
  |  
提交时间:2019/01/08
colonic drug delivery
polymers
lipids
pH-sensitive
10-hydroxycamptothecin
microspheres
biodistribution
bioavailability
A high-drug-loading self-assembled nanoemulsion enhances the oral absorption of probucol in rats
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL SCIENCES, 2013, 卷号: 102, 期号: 4, 页码: 1301-1306
作者:
Zhang, Zhiwen
;
Huang, Jian
;
Jiang, Shijun
;
Liu, Zeying
;
Gu, Wangwen
  |  
收藏
  |  
浏览/下载:93/0
  |  
提交时间:2019/01/08
nanoemulsion
self-assembly
bioavailability
poorly water-soluble drug
probucol
intestinal absorption
pharmacokinetics
calorimetry (DSC)
oral drug delivery
Investigation on in situ Gel Based on Liposomal Vesicle
期刊论文
OAI收割
chemical journal of chinese universities-chinese, 2013, 卷号: 34, 期号: 5, 页码: 1174-1179
Guan QX
;
Lu JW
;
Guo J
;
Ning ZL
;
Chen C
;
Yin JY
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2014/04/15
DRUG-DELIVERY
ENHANCED BIOAVAILABILITY
OCULAR DELIVERY
RELEASE
LUTEIN
NANOVESICLES
Simulation of the pharmacokinetics of bisoprolol in healthy adults and patients with impaired renal function using whole-body physiologically based pharmacokinetic modeling
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2012, 卷号: 33, 期号: 11, 页码: 1359
作者:
Li Guofu
;
Wang Kun
;
Chen Rui
;
Zhao Haoru
;
Yang Jin
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/12/24
TISSUE DISTRIBUTION
DRUG DISCOVERY
INTRASUBJECT VARIABILITY
PBPK SIMULATION
P-GP
ABSORPTION
POPULATION
PREDICTION
BIOAVAILABILITY
IDENTIFICATION
bisoprolol
whole-body physiologically based pharmacokinetic model
drug absorption
drug distribution
renal function impairment
Oral bioavailability and brain penetration of (-)-stepholidine, a tetrahydroprotoberberine agonist at dopamine D-1 and antagonist at D-2 receptors, in rats
期刊论文
OAI收割
BRITISH JOURNAL OF PHARMACOLOGY, 2009, 卷号: 158, 期号: 5, 页码: 1302-1312
作者:
Sun, Yan
;
Dai, Jieyu
;
Hu, Zheyi
;
Du, Feifei
;
Niu, Wei
  |  
收藏
  |  
浏览/下载:98/0
  |  
提交时间:2019/01/08
(-)-stepholidine
CNS drug
enterohepatic barrier
blood-brain barrier
oral bioavailability
brain penetration
metabolic profiling
prodrug
Enhanced circulation half-life of site-specific PEGylated rhG-CSF: Optimization of PEG molecular weight
期刊论文
OAI收割
JOURNAL OF BIOTECHNOLOGY, 2009, 卷号: 142, 期号: 3-4, 页码: 259-266
作者:
Zhai, Yanqin
;
Zhao, Yongjiang
;
Lei, Jiandu
;
Su, Zhiguo
;
Ma, Guanghui
收藏
  |  
浏览/下载:96/0
  |  
提交时间:2013/12/06
Drug bioavailability
Granulocyte colony stimulating factor (G-CSF)
Serum half-life
Site-specific PEGylation