中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [5]
合肥物质科学研究院 [3]
化学研究所 [2]
广州生物医药与健康研... [1]
武汉物理与数学研究所 [1]
采集方式
OAI收割 [12]
内容类型
期刊论文 [12]
发表日期
2025 [1]
2022 [1]
2021 [3]
2020 [2]
2017 [2]
2013 [1]
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学科主题
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REG3A secreted by peritumoral acinar cells enhances pancreatic ductal adenocarcinoma progression via activation of EGFR signaling
期刊论文
OAI收割
CELL COMMUNICATION AND SIGNALING, 2025, 卷号: 23, 期号: 1, 页码: 19
作者:
Ren, Xiaojing
;
Teng, Yunfei
;
Xie, Kunxin
;
He, Xiao
;
Chen, Gang
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2025/04/01
REG3A
Pancreatic ductal adenocarcinoma
Peritumoral acinar cell
Epidermal growth factor receptor (EGFR)
Paracrine
Optimization of Brigatinib as New Wild-Type Sparing Inhibitors of EGFR(T790M/C797S) Mutants
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2022, 页码: 7
作者:
Li, Shan
;
Zhang, Tao
;
Zhu, Su-Jie
;
Lei, Chong
;
Lai, Mengzhen
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2022/06/15
Epidermal Growth Factor Receptor (EGFR)
Resistant Mutation
C797S
Antitumor
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
OAI收割
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
  |  
收藏
  |  
浏览/下载:108/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
Clinical outcomes of lung adenocarcinoma patients harboring uncommon epidermal growth factor receptor (EGFR) mutations treated with EGFR-tyrosine kinase inhibitors (TKIs)
期刊论文
OAI收割
ANNALS OF PALLIATIVE MEDICINE, 2021
作者:
Si, Jinfei
;
Gu, Xiaodong
;
Wang, Wenxian
;
Ying, Shenpeng
;
Song, Zhengbo
  |  
收藏
  |  
浏览/下载:86/0
  |  
提交时间:2022/02/14
Epidermal growth factor receptor (EGFR)
uncommon mutation
compound mutation
double uncommon mutation
lung adenocarcinoma (lung AC)
MD2 blockage prevents the migration and invasion of hepatocellular carcinoma cells via inhibition of the EGFR signaling pathway
期刊论文
OAI收割
JOURNAL OF GASTROINTESTINAL ONCOLOGY, 2021
作者:
Qi, Yajun
;
Fang, Qilu
;
Li, Qinglin
;
Ding, Haiying
;
Shu, Qi
  |  
收藏
  |  
浏览/下载:94/0
  |  
提交时间:2021/09/06
Hepatocellular carcinoma (HCC)
myeloid differentiation protein 2 (MD2)
epidermal growth factor receptor (EGFR)
migration
invasion
Tumor Mutation Burden Correlates With Efficacy of Chemotherapy/Targeted Therapy in Advanced Non-Small Cell Lung Cancer
期刊论文
OAI收割
FRONTIERS IN ONCOLOGY, 2020, 卷号: 10
作者:
Lin, Chen
;
Shi, Xun
;
Zhao, Jun
;
He, Qiong
;
Fan, Yun
  |  
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2020/10/26
tumor mutation burden (TMB)
clinical benefit
epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs)
chemotherapy
non-small cell lung cancer (NSCLC)
Design and synthesis of selective degraders of EGFR(L858R/T790M) mutant
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 192, 页码: 14
作者:
Zhang, Xin
;
Xu, Fang
;
Tong, Linjiang
;
Zhang, Tao
;
Xie, Hua
  |  
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2020/07/01
Epidermal growth factor receptor (EGFR)
Resistance
Proteolysis targeting chimera (PROTAC)
Protein degradation
Facile Synthesis of Novel Perfluorocarbon-Modulated 4-Anilinoquinazoline Analogues
期刊论文
OAI收割
CHINESE JOURNAL OF CHEMISTRY, 2017, 卷号: 35, 期号: 11, 页码: 1693-1700
作者:
Shi, Huiping
;
Lai, Bonan
;
Chen, Shizhen
;
Zhou, Xin
;
Nie, Jing
  |  
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2018/11/05
4-anilinoquinazolines
Perfluorocarbon (Pfc)
Nucleophilic Substitution Reaction
Synthesis
Epidermal Growth Factor Receptor (Egfr)
Single-molecule imaging reveals the stoichiometry change of epidermal growth factor receptor during transactivation by beta(2)-adrenergic receptor
期刊论文
OAI收割
SCIENCE CHINA-CHEMISTRY, 2017, 卷号: 60, 期号: 10, 页码: 1310-1317
作者:
Zhang, Mingliang
;
He, Kangmin
;
Wu, Jimin
;
Li, Nan
;
Yuan, Jinghe
  |  
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2018/04/25
Transactivation
Epidermal Growth Factor Receptor (Egfr)
Beta(2)-adrenergic Receptor (Beta(2)-ar)
Single Molecule Imaging
Synthesis, characterization, screening and docking analysis of 4-anilinoquinazoline derivatives as tyrosine kinase inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 61, 页码: 84-94
作者:
Lu, Shuang
;
Zheng, Wei
;
Ji, Liyun
;
Luo, Qun
;
Hao, Xiang
  |  
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2019/04/09
Receptor Tyrosine Kinase
Epidermal Growth Factor Receptor (Egfr)
Anilinoquinazoline
Inhibitor
Docking Analysis