中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [6]
采集方式
OAI收割 [6]
内容类型
期刊论文 [6]
发表日期
2025 [1]
2023 [2]
2022 [1]
2021 [1]
2018 [1]
学科主题
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Concurrent inhibition of p300/CBP and FLT3 enhances cytotoxicity and overcomes resistance in acute myeloid leukemia
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 14
作者:
Chen, Yu-jun
;
Zhao, Yu
;
Yao, Ming-yue
;
Wang, Ya-fang
;
Ma, Ming
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
acute myeloid leukemia
FLT3
p300/CBP
quizartinib resistance
combination strategy
Design, synthesis and biological evaluation of 2-aminopyrimidine derivatives as potent FLT3 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 96, 页码: 5
作者:
Lian, Xuanmin
;
Gao, Yue
;
Li, Xuemei
;
Wang, Peipei
;
Tong, Lexian
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/12/11
2-aminopyrimidine
FLT3 inhibitors
MV4-11
FLT3 mutations
Design, synthesis, and evaluation of pyrido.[3,4-b]pyrazin-2(1H)-one derivatives as potent FLT3 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 79, 页码: 117155
作者:
Sun, Mei
;
Wang, Chang
;
Wang, Peipei
;
Ye, Qingqing
;
Zhou, Yubo
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/04/09
FLT3
FLT3-D835Y
Acute myeloid leukemia
Structure -activity relationships
BCL-2 inhibitor synergizes with PI3K delta inhibitor and overcomes FLT3 inhibitor resistance in acute myeloid leukaemia
期刊论文
OAI收割
AMERICAN JOURNAL OF CANCER RESEARCH, 2022, 卷号: 12, 期号: 8, 页码: 3829-3842
作者:
Yao, Ming-Yue
;
Wang, Ya-Fang
;
Zhao, Yu
;
Ling, Li-Jun
;
He, Ye
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/12/13
Acute myeloid leukaemia
BCL-2
PI3K delta
FLT3
synergistic lethality
Discovery and structure - activity relationship exploration of pyrazolo [1,5-a]pyrimidine derivatives as potent FLT3-ITD inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 48, 页码: 13
作者:
Chen, Yun
;
Bai, Gang
;
Li, Yan
;
Ning, Yi
;
Cao, Sufen
  |  
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2021/12/01
FLT3
FLT3-ITD
Acute myeloid leukemia
Structure-activity relationships
Pyrazolo[1, 5-a]pyrimidine
Combined inhibition of PI3K delta and FLT3 signaling exerts synergistic antitumor activity and overcomes acquired drug resistance in FLT3-activated acute myeloid leukemia
期刊论文
OAI收割
CANCER LETTERS, 2018, 卷号: 420, 页码: 49-59
作者:
He, Ye
;
Sun, Liping
;
Xu, Yongping
;
Fu, Li
;
Li, Yun
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2019/01/08
Acute myeloid leukemia
FLT3
PI3K delta
CAL101
Synergistic effect