中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [6]
大连化学物理研究所 [2]
昆明动物研究所 [2]
昆明植物研究所 [1]
上海应用物理研究所 [1]
采集方式
OAI收割 [11]
iSwitch采集 [1]
内容类型
期刊论文 [12]
发表日期
2020 [2]
2019 [4]
2018 [2]
2017 [2]
2014 [1]
2010 [1]
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学科主题
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Discovery of Novel IDH1 Inhibitor Through Comparative Structure-Based Virtual Screening
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2020, 卷号: 11, 页码: 11
作者:
Wang, Yuwei
;
Tang, Shuai
;
Lai, Huanling
;
Jin, Ruyi
;
Long, Xu
  |  
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2020/12/24
IDH1
gliomas
molecular docking
virtual screening
docking-based virtual screening
Licochalcone A suppresses the proliferation of sarcoma HT-1080 cells, as a selective R132C mutant IDH1 inhibitor
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 5
作者:
Hu, Chujiao
;
Zuo, Yu
;
Liu, Jingqiu
;
Xu, Heng
;
Liao, Weike
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
Licochalcone A
Mutant IDH1
Selective inhibitor
Discovery of DC_H31 as potential mutant IDH1 inhibitor through NADPH-based high throughput screening
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3229-3236
作者:
Duan, Zhe
;
Liu, Jingqiu
;
Niu, Liping
;
Wang, Jun
;
Feng, Mingqian
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/07/01
IDH1 mutation
High-throughput screening
Pan-inhibitor
2-HG
Gliomas
Integrated Metabolomics and Lipidomics Analyses Reveal Metabolic Reprogramming in Human Glioma with IDH1 Mutation
期刊论文
OAI收割
JOURNAL OF PROTEOME RESEARCH, 2019, 卷号: 18, 期号: 3, 页码: 960-969
作者:
Xu, Guowang
;
Zhou, Lina
;
Wang, Zhichao
;
Hu, Chunxiu
;
Zhang, Chaoqi
  |  
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2019/06/20
glioma
IDH1
metabolomics
lipidomics
metabolic reprogramming
Integrated metabolomics and lipidomics analyses reveal metabolic reprogramming in human glioma with idh1 mutation
期刊论文
iSwitch采集
Journal of proteome research, 2019, 卷号: 18, 期号: 3, 页码: 960-969
作者:
Zhou, Lina
;
Wang, Zhichao
;
Hu, Chunxiu
;
Zhang, Chaoqi
;
Kovatcheva-Datchary, Petia
收藏
  |  
浏览/下载:108/0
  |  
提交时间:2019/05/08
Glioma
Idh1
Metabolomics
Lipidomics
Metabolic reprogramming
Synthesis and biological evaluation of 3-aryl-4-indolyl-maleimides as potent mutant isocitrate dehydrogenase-1 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 4, 页码: 589-603
作者:
Liu, Xiaoqi
;
Hu, Yuanyuan
;
Gao, Anhui
;
Xu, Meng
;
Gao, Lixin
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/01
3-Aryl-4-indolyl-maleimides
IDH1/R132H inhibitors
Tumor 2-HG
Synthesis
Discovery and structure-activity-relationship study of novel imidazole cyclopropyl amine analogues for mutant isocitric dehydrogenase 1 (IDH1) inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3808-3812
作者:
Zheng, Qiangang
;
Chen, Ziqi
;
Wan, Huixin
;
Tang, Shuai
;
Ye, Yan
  |  
收藏
  |  
浏览/下载:255/0
  |  
提交时间:2019/01/08
IDH1 inhibitor
Imidazole cyclopropyl amine
Structure-based rational design
A New Breviane Spiroditerpenoid from the Marine-Derived Fungus Penicillium sp TJ403-1
期刊论文
OAI收割
MARINE DRUGS, 2018, 卷号: 16, 期号: 4, 页码: 110
作者:
Yang, Beiye
;
Sun, Weiguang
;
Wang, Jianping
;
Lin, Shuang
;
Li, Xiao-Nian
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2018/07/02
Marine-derived Fungi
Penicillium Sp Tj403-1
Breviane Spiroditerpenoid
Idh1 Inhibitory Activity
Cytotoxicity
Discovery and structure-activity-relationship study of novel conformationally restricted indane analogues for mutant isocitric dehydrogenase 1 (IDH1) inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 23, 页码: 5262-5266
作者:
Zheng, Qiangang
;
Tang, Shuai
;
Fu, Xianlei
;
Chen, Ziqi
;
Ye, Yan
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/01/08
IDH1 inhibitor
Indane amide
Structure-based rational design
Isomers Identification of 2-hydroxyglutarate acid disodium salt (2HG) by Terahertz Time-domain Spectroscopy
期刊论文
OAI收割
SCIENTIFIC REPORTS, 2017, 卷号: 7, 期号: -, 页码: -
作者:
Chen, WQ
;
Peng, Y
;
Jiang, XK
;
Zhao, JY
;
Zhao, HW
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2018/08/30
Magnetic-resonance-spectroscopy
Density-functional Theory
Gliomas
(r)-2-hydroxyglutarate
Radiation
Cancer
Idh1