中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
上海药物研究所 [10]
昆明植物研究所 [10]
成都生物研究所 [3]
大连化学物理研究所 [3]
中国科学院大学 [3]
西北高原生物研究所 [2]
更多
采集方式
OAI收割 [33]
iSwitch采集 [4]
内容类型
期刊论文 [35]
学位论文 [2]
发表日期
2024 [2]
2023 [2]
2021 [2]
2020 [1]
2019 [2]
2018 [3]
更多
学科主题
Chemistry [2]
Chemistry,... [2]
药物化学 [2]
Biochemist... [1]
Chemistry,... [1]
Chemistry,... [1]
更多
筛选
浏览/检索结果:
共37条,第1-10条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
题名升序
题名降序
提交时间升序
提交时间降序
作者升序
作者降序
发表日期升序
发表日期降序
A novel isoquinoline alkaloid HJ-69 isolated from Zanthoxylum bungeanum attenuates inflammatory pain by inhibiting voltage-gated sodium and potassium channels
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2024, 卷号: 330, 页码: 12
作者:
Wang, Long
;
Hao, Haishuang
;
Meng, Xianhua
;
Zhang, Wenbo
;
Zhang, Yin
  |  
收藏
  |  
浏览/下载:113/0
  |  
提交时间:2024/11/05
HJ-69
Zanthoxylum bungeanum
Isoquinoline alkaloid
Nav
Kv
Inflammatory pain
Synthesis of Indene[1,2-
c
] isoquinoline-11-one by Rhodium-catalyzed Benzimide-directed C-H Activation
期刊论文
OAI收割
ACTA CHIMICA SINICA, 2024, 卷号: 82, 期号: 6, 页码: 565-569
作者:
Huang Jiaxin
;
Liu Min
;
Xu Hui
;
Dai Hui-Xiong
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/10/21
indene[1,2-c]isoquinoline
C-H activation
rhodium catalyst
Design, synthesis and biological evaluation of chalcone derivatives as potent and orally active hCYP3A4 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 95, 页码: 9
作者:
Lu, Shiwei
;
Zhang, Feng
;
Gong, Jiahao
;
Huang, Jian
;
Zhu, Guanghao
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/12/08
Cytochrome P450 3A4 (CYP3A4)
Inhibitors
Isoquinoline chalcones
Orally active
Discovery and biological evaluation of a new type of dual inhibitors of indoleamine 2,3-dioxygenase 1 and tryptophan 2,3-dioxygenase from ethnomedicinal plant Dactylicapnos scandens
期刊论文
OAI收割
PHYTOCHEMISTRY, 2023, 卷号: 214, 页码: 113794
作者:
Bao,Mei-Fen
;
Yang,Xin-Ni
;
Wu,Jing
;
Liu,Jiang-Xin
;
Cai,Xiang-Hai
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/07/25
Dactylicapnos scandens (D. don) hutch.
Isoquinoline alkaloids
Aporphine-type alkaloids
Dactycapnine a
IDO1/TDO dual inhibitor
APORPHINE ALKALOIDS
N-OXIDE
INFLAMMATION
PATHWAY
THALIPORPHINE
COMPLEXES
CANCER
ROOTS
Rhodium-Catalyzed C-H Activation/Annulation Cascade of Aryl Oximes and Propargyl Alcohols to Isoquinoline N-Oxides
期刊论文
OAI收割
ADVANCED SYNTHESIS & CATALYSIS, 2021, 页码: 7
作者:
Li, Yuan
;
Fang, Feifei
;
Zhou, Jianhui
;
Li, Jiyuan
;
Wang, Run
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2021/08/17
Isoquinoline N-oxides
beta-hydroxy elimination
Rhodium
Secondary propargyl alcohols
Diverse isoquinolines with anti-inflammatory and analgesic bioactivities from Hypecoum erectum
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 270, 页码: 113811
作者:
Yuan,Hai-Lian
;
Zhao,Yun-Li
;
Qin,Xu-Jie
;
Liu,Ya-Ping
;
Yang,Xing-Wei
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2022/04/02
Hypecoum erectum
Isoquinoline alkaloids
Anti-inflammatory activity
Analgesic activity
Inflammatory mediators
Preparative separation of isoquinoline alkaloids from Corydalis impatiens using middle chromatogram isolated gel column coupled with positively charged reversed-phase liquid chromatography
期刊论文
OAI收割
JOURNAL OF SEPARATION SCIENCE, 2020, 卷号: 43, 期号: 13
作者:
Wang, Qi
;
Chen, Wenjie
;
Wang, Qilan
;
Tao, Yanduo
;
Yu, Ruitao
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/11/25
isoquinoline alkaloids
preparative separation
positive charge
traditional Tibetan medicine
Organo-Catalyzed Asymmetric Amination of 4-Arylisoquinoline-1,3(2H,4H)-dione Derivatives in the Construction of Quaternary Stereocenters
期刊论文
OAI收割
ADVANCED SYNTHESIS & CATALYSIS, 2019, 页码: 6
作者:
Cheng, Cheng
;
Li, Ying-Xian
;
Zhang, Ji-Quan
;
Zhao, Yong-Long
;
Zhang, Lin
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
Isoquinoline-1,3(2H,4H)-dione
Amination reaction
Asymmetric catalysis
Bifunctional catalyst
Preparative separation of isoquinoline alkaloids from Corydalis impatiens using a middle-pressure chromatogram isolated gel column coupled with two-dimensional liquid chromatography
期刊论文
OAI收割
JOURNAL OF SEPARATION SCIENCE, 2019, 卷号: 42, 期号: 20
作者:
Pan, Guoqing
;
Shen, Jianwei
;
Ma, Yuhua
;
He, Yanfeng
;
Bao, Yi
  |  
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2019/11/26
Corydalis impatiens
isoquinoline alkaloids
preparative separation
two-dimensional liquid chromatography
Discovery of new potent protein arginine methyltransferase 5 (PRMT5) inhibitors by assembly of key pharmacophores from known inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3693-3699
作者:
Zhu, Kongkai
;
Song, Jia-Li
;
Tao, Hong-Rui
;
Cheng, Zhi-Qiang
;
Jiang, Cheng-Shi
  |  
收藏
  |  
浏览/下载:113/0
  |  
提交时间:2019/01/08
Pharmacophore combination
Isoquinoline
PRMT5 inhibitor
Molecular docking
Molecular dynamics simulation