机构

• 上海神经科学研究所 [6]
• 上海药物研究所 [5]
• 金属研究所 [3]
• 上海生物化学与细胞生... [2]
• 昆明植物研究所 [1]

采集方式

• OAI收割 [17]

内容类型

• 期刊论文 [17]

发表日期

• 2019 [1]
• 2015 [1]
• 2014 [2]
• 2013 [3]
• 2011 [2]
• 2008 [4]
• 更多

学科主题

• Neuroscien... [4]
• Biochemist... [2]
• Developmen... [2]
• Biochemist... [1]
• Biochemist... [1]
• Cell Biolo... [1]
• 更多

筛选

浏览/检索结果: 共17条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 3-Deoxy-2 beta,16-dihydroxynagilactone E, a natural compound from Podocarpus nagi, preferentially inhibits JAK2/STAT3 signaling by allosterically interacting with the regulatory domain of JAK2 and induces apoptosis of cancer cells 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1578-1586 作者:  Shan, Hui;  Yao, Sheng;  Ye, Yang;  Yu, Qiang   |  收藏  |  浏览/下载：21/0  |  提交时间：2020/07/01 JAK/STAT  3-deoxy-2 beta,16-dihydroxynagilactone E  tyrosine kinase inhibitor  allosteric inhibitor  cancer   Synthesis and biological evaluation of 3-([1,2,4]triazolo [4,3-a]pyridin-3-yl)-4-(indol-3-yl)-maleimides as potent, selective GSK-3 beta inhibitors and neuroprotective agents 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2015, 卷号: 23, 期号: 5, 页码: 1179-1188 作者:  Ye, Qing;  Mao, Weili;  Zhou, Yubo;  Xu, Lei;  Li, Qiu   |  收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08 GSK-3 beta inhibitors  Maleimides  Kinase activity  Neuroprotective agents   Isoindolone derivative QSN-10c induces leukemic cell apoptosis and suppresses angiogenesis via PI3K/AKT signaling pathway inhibition 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 5, 页码: 625-635 作者:  Lv Wenwen;  Qin Sining;  Chen Congqin;  Zhang Jinjie;  Ren Tianshu   |  收藏  |  浏览/下载：13/0  |  提交时间：2021/02/02 ENDOTHELIAL GROWTH-FACTOR  DRUG-INDUCED APOPTOSIS  HEMATOLOGICAL MALIGNANCIES  ACTIN REORGANIZATION  ANTICANCER DRUG  BONE-MARROW  KINASE AKT  CANCER  THALIDOMIDE  MIGRATION  isoindolone  anticancer drug  leukemia  zebrafish  angiogenesis  apoptosis  AKT  GSK3 beta   Isoindolone derivative QSN-10c induces leukemic cell apoptosis and suppresses angiogenesis via PI3K/AKT signaling pathway inhibition 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 5, 页码: 625-635 作者:  Lv Wenwen;  Qin Sining;  Chen Congqin;  Zhang Jinjie;  Ren Tianshu   |  收藏  |  浏览/下载：16/0  |  提交时间：2021/02/02 ENDOTHELIAL GROWTH-FACTOR  DRUG-INDUCED APOPTOSIS  HEMATOLOGICAL MALIGNANCIES  ACTIN REORGANIZATION  ANTICANCER DRUG  BONE-MARROW  KINASE AKT  CANCER  THALIDOMIDE  MIGRATION  isoindolone  anticancer drug  leukemia  zebrafish  angiogenesis  apoptosis  AKT  GSK3 beta   Small-molecule modulation of Wnt signaling via modulating the Axin-LRP5/6 interaction 期刊论文  OAI收割 NATURE CHEMICAL BIOLOGY, 2013, 卷号: 9, 期号: 9, 页码: 579-U82 作者:  Wang, Sheng;  Yin, Junlin;  Chen, Duozhi;  Nie, Fen;  Song, Xiaomin   |  收藏  |  浏览/下载：47/0  |  提交时间：2013/10/16 Glycogen-synthase Kinase-3  Beta-catenin  Negative Regulator  Dix Domain  Stem-cells  In-vivo  Axin  Activation  Pathway  Phosphorylation   Lithium treatment induces proteasomal degradation of over-expressed acetylcholinesterase (AChE-S) and inhibit GSK3 beta 期刊论文  OAI收割 CHEMICO-BIOLOGICAL INTERACTIONS, 2013, 卷号: 203, 期号: 1, 页码: 309-313 作者:  Jing, P;  Zhang, JY;  Ouyang, Q;  Wu, J;  Zhang, XJ 收藏  |  浏览/下载：46/0  |  提交时间：2015/07/22 Acetylcholinesterase (AChE)  Glycogen synthase kinase-3 beta (GSK3 beta)  HEK293T cells  Proteasome   Design,synthesis and biological evaluation of benzothiazinones as novel non-ATP competitive inhibitors of glycogen synthesis kinase 3beta (GSK-3beta) 期刊论文  OAI收割 Chinese Journal of Medicinal Chemistry, 2013, 卷号: 23, 期号: 6, 页码: 444-452 作者:  Lu Wenbo;  Zhang Peng;  Huang Ke;  Chu Yong;  Ye Deyong   |  收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08 GSK-3beta  synthesis  benzothiazinones  glycogen synthesis kinase 3beta  non-ATP competitive inhibitor  structure-activity relationships   Exposure to Pyrithiamine Increases beta-Amyloid Accumulation, Tau Hyperphosphorylation, and Glycogen Synthase Kinase-3 Activity in the Brain 期刊论文  OAI收割 NEUROTOXICITY RESEARCH, 2011, 卷号: 19, 期号: 4, 页码: 575-583 Zhao, Jing; Sun, Xiaojing; Yu, Zhe; Pan, Xiaoli; Gu, Fenghua; Chen, Jia; Dong, Wenxin; Zhao, Lei; Zhong, Chunjiu 收藏  |  浏览/下载：28/0  |  提交时间：2012/07/13 Alzheimer's disease  Thiamine deficiency  Pyrithiamine  Glycogen synthase kinase-3  POSITRON-EMISSION-TOMOGRAPHY  FAMILIAL ALZHEIMERS-DISEASE  THIAMINE-DEPENDENT ENZYMES  TRANSGENIC MICE  WERNICKES ENCEPHALOPATHY  INSULIN-RESISTANCE  PRECURSOR PROTEIN  MOUSE MODELS  A-BETA  DEFICIENCY   Implication of Wnt Signaling in Neuronal Polarization 期刊论文  OAI收割 DEVELOPMENTAL NEUROBIOLOGY, 2011, 卷号: 71, 期号: 6, 页码: 495-507 作者:  Luo, Zhen-Ge 收藏  |  浏览/下载：42/0  |  提交时间：2012/07/13 Wnt  neuronal polarization  axon development  cytoskeleton  ADENOMATOUS POLYPOSIS-COLI  GLYCOGEN-SYNTHASE KINASE-3-BETA  ASYMMETRIC CELL DIVISIONS  C-ELEGANS EMBRYOS  BETA-CATENIN  CAENORHABDITIS-ELEGANS  XENOPUS EMBRYOS  AXON FORMATION  AXIS FORMATION  CORTICAL-NEURONS