中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共17条,第1-10条 帮助

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3-Deoxy-2 beta,16-dihydroxynagilactone E, a natural compound from Podocarpus nagi, preferentially inhibits JAK2/STAT3 signaling by allosterically interacting with the regulatory domain of JAK2 and induces apoptosis of cancer cells 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1578-1586
作者:  
Shan, Hui;  Yao, Sheng;  Ye, Yang;  Yu, Qiang
  |  收藏  |  浏览/下载:19/0  |  提交时间:2020/07/01
Synthesis and biological evaluation of 3-([1,2,4]triazolo [4,3-a]pyridin-3-yl)-4-(indol-3-yl)-maleimides as potent, selective GSK-3 beta inhibitors and neuroprotective agents 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2015, 卷号: 23, 期号: 5, 页码: 1179-1188
作者:  
Ye, Qing;  Mao, Weili;  Zhou, Yubo;  Xu, Lei;  Li, Qiu
  |  收藏  |  浏览/下载:27/0  |  提交时间:2019/01/08
Isoindolone derivative QSN-10c induces leukemic cell apoptosis and suppresses angiogenesis via PI3K/AKT signaling pathway inhibition 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 5, 页码: 625-635
作者:  
Lv Wenwen;  Qin Sining;  Chen Congqin;  Zhang Jinjie;  Ren Tianshu
  |  收藏  |  浏览/下载:9/0  |  提交时间:2021/02/02
Isoindolone derivative QSN-10c induces leukemic cell apoptosis and suppresses angiogenesis via PI3K/AKT signaling pathway inhibition 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 5, 页码: 625-635
作者:  
Lv Wenwen;  Qin Sining;  Chen Congqin;  Zhang Jinjie;  Ren Tianshu
  |  收藏  |  浏览/下载:12/0  |  提交时间:2021/02/02
Small-molecule modulation of Wnt signaling via modulating the Axin-LRP5/6 interaction 期刊论文  OAI收割
NATURE CHEMICAL BIOLOGY, 2013, 卷号: 9, 期号: 9, 页码: 579-U82
作者:  
Wang, Sheng;  Yin, Junlin;  Chen, Duozhi;  Nie, Fen;  Song, Xiaomin
  |  收藏  |  浏览/下载:42/0  |  提交时间:2013/10/16
Lithium treatment induces proteasomal degradation of over-expressed acetylcholinesterase (AChE-S) and inhibit GSK3 beta 期刊论文  OAI收割
CHEMICO-BIOLOGICAL INTERACTIONS, 2013, 卷号: 203, 期号: 1, 页码: 309-313
作者:  
Jing, P;  Zhang, JY;  Ouyang, Q;  Wu, J;  Zhang, XJ
收藏  |  浏览/下载:43/0  |  提交时间:2015/07/22
Design,synthesis and biological evaluation of benzothiazinones as novel non-ATP competitive inhibitors of glycogen synthesis kinase 3beta (GSK-3beta) 期刊论文  OAI收割
Chinese Journal of Medicinal Chemistry, 2013, 卷号: 23, 期号: 6, 页码: 444-452
作者:  
Lu Wenbo;  Zhang Peng;  Huang Ke;  Chu Yong;  Ye Deyong
  |  收藏  |  浏览/下载:33/0  |  提交时间:2019/01/08
Exposure to Pyrithiamine Increases beta-Amyloid Accumulation, Tau Hyperphosphorylation, and Glycogen Synthase Kinase-3 Activity in the Brain 期刊论文  OAI收割
NEUROTOXICITY RESEARCH, 2011, 卷号: 19, 期号: 4, 页码: 575-583
Zhao, Jing; Sun, Xiaojing; Yu, Zhe; Pan, Xiaoli; Gu, Fenghua; Chen, Jia; Dong, Wenxin; Zhao, Lei; Zhong, Chunjiu
收藏  |  浏览/下载:23/0  |  提交时间:2012/07/13
Implication of Wnt Signaling in Neuronal Polarization 期刊论文  OAI收割
DEVELOPMENTAL NEUROBIOLOGY, 2011, 卷号: 71, 期号: 6, 页码: 495-507
作者:  
Luo, Zhen-Ge
收藏  |  浏览/下载:41/0  |  提交时间:2012/07/13