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浏览/检索结果: 共1089条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of a 1,6-naphthyridin-4-one-based AXL inhibitor with improved pharmacokinetics and enhanced in vivo antitumor efficacy 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 17 作者:  Lan, Yaohan;  Peng, Xia;  Ji, Yinchun;  Su, Yi;  Duan, Wenhu   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/02/27 AXL inhibitor  In vivo antitumor efficacy  6-Naphthyridin-4-one derivatives  Scaffold hopping  Structure-based drug design   pH-responsive nanogels with enhanced antioxidant and antitumor activities on drug delivery and smart drug release 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2024, 卷号: 257, 页码: 16 作者:  Ma, Bing;  Li, Qing;  Mi, Yingqi;  Zhang, Jingjing;  Tan, Wenqiang   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/01/26 Benzimidazole-chitosan quaternary ammonium  salt  Nanogels  pH-responsive  Antioxidant activity  Antitumor activity   JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers 期刊论文  OAI收割 CANCER LETTERS, 2024, 卷号: 582, 页码: 15 作者:  Lu, Xuxiu;  Yu, Rilei;  Li, Zhen;  Yang, Mengke;  Dai, Jiajia   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/04/07 Acquired resistance  Cancer  NSCLC  JC-010a  SHP2   The promise and challenges of combination therapies with antibody-drug conjugates in solid tumors 期刊论文  OAI收割 JOURNAL OF HEMATOLOGY & ONCOLOGY, 2024, 卷号: 17, 期号: 1, 页码: 32 作者:  Wei, Qing;  Li, Peijing;  Yang, Teng;  Zhu, Jiayu;  Sun, Lu   |  收藏  |  浏览/下载：23/0  |  提交时间：2024/02/27 Antibody-drug conjugate  Solid tumor  Combination therapy  Immunotherapy  Targeted therapy   Dual stimuli-activatable versatile nanoplatform for photodynamic therapy and chemotherapy of triple-negative breast cancer 期刊论文  OAI收割 CHINESE CHEMICAL LETTERS, 2023, 卷号: 34, 期号: 12, 页码: 9 作者:  Xu, Jie;  Lai, Yi;  Wang, Fengyang;  Zou, Zhifeng;  Pei, Renjun   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/12/08 Cancer theranostics  Precise therapy  Combinatorial therapy  Photodynamic therapy  Triple-negative breast cancer   Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 19 作者:  Wang, Pingyuan;  Zhu, Wen-Ting;  Wang, Yajing;  Song, Shan-Shan;  Xi, Yong   |  收藏  |  浏览/下载：58/0  |  提交时间：2023/10/17 PARP1 inhibitor  Synthetic lethality  Drug resistance  Anticancer  Structure -activity relationship   The anticancer potential of chemical constituents of Moringa oleifera targeting CDK-2 inhibition in estrogen receptor positive breast cancer using in-silico and in vitro approches 期刊论文  OAI收割 BMC COMPLEMENTARY MEDICINE AND THERAPIES, 2023, 卷号: 23, 期号: 1, 页码: 17 作者:  Sultan, Rida;  Ahmed, Abrar;  Wei, Li;  Saeed, Hamid;  Islam, Muhammad   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/12/19 CDK2  ER+ Breast cancer  Molecular Docking  MM-GBSA  Molecular Dynamic Simulations  MTT assay  Moringa oleifera  Phytoconstituents  Chlorogenic acid   Discovery, Structure-Activity Relationship and In Vitro Anticancer Activity of Small-Molecule Inhibitors of the Protein-Protein Interactions between AF9/ENL and AF4 or DOT1L 期刊论文  OAI收割 CANCERS, 2023, 卷号: 15, 期号: 21, 页码: 28 作者:  Li, Xin;  Wu, Xiaowei;  Nie, Shenyou;  Zhao, Jidong;  Yao, Yuan   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/12/19 MLL-rearranged leukemia  super elongation complexes  small-molecule inhibitor  protein-protein interaction  cancer therapeutics   Proteasome inhibitors reduce CD73 expression partly via decreasing p-ERK in NSCLC cells 期刊论文  OAI收割 LIFE SCIENCES, 2023, 卷号: 332, 页码: 10 作者:  Su, Ai-Ling;  Tian, Chang-Qing;  Ou, Ying-Jie;  Bao, Xu-Bin;  Huan, Xia-Juan   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/12/08 CD73  Proteasome inhibitors  ERK  NSCLC   Chemical Inhibitors Targeting the Oncogenic m6A Modifying Proteins 期刊论文  OAI收割 ACCOUNTS OF CHEMICAL RESEARCH, 2023, 卷号: 56, 期号: 21, 页码: 3010-3022 作者:  Huang, Yue;  Xia, Wenyang;  Dong, Ze;  Yang, Cai-Guang   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/11