中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [182]
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昆明植物研究所 [22]
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期刊论文 [294]
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Development and validation of an LC-MS/MS method with precolumn derivatization for the determination of dimethoxyethyl phthalate metabolites ethylene glycol methyl ether and methoxyacetic acid in rat plasma
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2025, 卷号: 261, 页码: 8
作者:
Cui, Xinran
;
Wang, Yongbin
;
Zhan, Yan
;
Chen, Xiaoyan
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/05/27
LC-MS/MS
Derivatization
Ethylene glycol methyl ether
Methoxyacetic acid
Dimethoxyethyl phthalate
A holistic strategy for the in-depth discrimination and authentication of 16 citrus herbs and associated commercial products based on machine learning techniques and non-targeted metabolomics
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY A, 2025, 卷号: 1745, 页码: 12
作者:
Huang, Yu-shi
;
An, Ya-ling
;
Zheng, Yue-yuan
;
Zhao, Wen-jie
;
Song, Chun-qian
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2025/04/01
Citrus herbs
Discrimination
LC-MS
Machine learning
Differential markers
Quantification of serum daratumumab in multiple myeloma patients by LC-MS/MS, comparison with ELISA
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2025, 卷号: 255, 页码: 7
作者:
Li, Weiqiang
;
Tian, Zhuoran
;
Yu, Xiong
;
Xu, Hongyu
;
Huang, Fang
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2025/02/28
Multiple myeloma
Daratumumab
LC-MS/MS
Surrogate peptide
Diazonium-based derivatization for enhanced detection of phosphorylated metabolites by LC-MS in cells
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2025, 卷号: 255, 页码: 7
作者:
Wang, Yikang
;
Lin, Feifei
;
Zhu, Guozheng
;
Zhou, Xiaoxue
;
Hu, Youhong
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/04/01
Phosphorylated metabolite
Derivatization
Chromatographic separation
Quantitative analysis
LC-MS
The critical role of MLKL in hemorrhagic stroke and the therapeutic potential of its associated protein network
期刊论文
OAI收割
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2025, 卷号: 12, 页码: 12
作者:
Wang, Yi
;
Xu, Moran
;
Zuo, Xiaoli
;
Wang, Sheng
;
Yu, Yong
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2025/04/01
mlkl
ICH
hemorrhagic stroke
neuroinflammation
LC-MS/MS
Quantification of crisugabalin (HSK16149) in biological matrix by LC-MS/ MS method: An application to rat pharmacokinetic and tissue distribution studies
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2025, 卷号: 1251, 页码: 9
作者:
Wang, Zeyu
;
Tang, Pingming
;
Dou, Caixia
;
Shen, Jiale
;
Peng, Ni
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/04/01
Crisugabalin (HSK16149)
LC-MS/MS
Pharmacokinetics
Tissue distribution
Simultaneous Quantification of Total Antibody and Conjugated Payload for DS001 in Rat Serum Using a Hybrid Immuno-Capture LC-MS/MS
期刊论文
OAI收割
AAPS JOURNAL, 2025, 卷号: 27, 期号: 1, 页码: 13
作者:
Yu, Xiong
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2025/04/01
ADC
LC-MS/MS
payload
simultaneous quantification
total antibody
An automatic LC-MS/MS data analysis workflow for herbal compound annotation with AutoAnnotatoR: A case study of ten botanical origins of Fritillaria species
期刊论文
OAI收割
PHYTOMEDICINE, 2024, 卷号: 135, 页码: 12
作者:
An, Ya-ling
;
Li, Jia-yuan
;
Wei, Wen-long
;
Li, Yun
;
Zhang, Jian-qing
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/12/11
Botanical natural products
Automatic compound annotation
LC-MS/MS
AutoAnnotatoR
Analysis of Herbal Constituents and In Vivo Pharmacokinetics of
Gegen-Huangqi
Decoction in Rat Plasma Using HPLC-Q-TOF-MS/MS and HPLC-QQQ-MS/MS
期刊论文
OAI收割
BIOMEDICAL CHROMATOGRAPHY, 2024, 页码: 16
作者:
Xu, Zhou
;
Wang, Linwei
;
Liu, Huan
;
Tian, Xiaoting
;
Wang, Yangyang
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/12/25
gegen-huangqi
decoction
hepatic disposition
LC-MS/MS
pharmacokinetics
qualitative
Simultaneous determination of unecritinib (TQ-B3101) and its active metabolite crizotinib in rat plasma by LC-MS/MS:An application to pharmacokinetic studies
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2024, 卷号: 246, 页码: 9
作者:
Wang, Hong
;
Chen, Huixian
;
Cui, Xinran
;
Zhang, Yuchen
;
Zhou, Jialan
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/07/12
Unecritinib (TQ-B3101)
Crizotinib
Carboxylesterases
LC-MS/MS
Hydrolytic metabolism