机构

• 海洋研究所 [7]
• 上海药物研究所 [5]
• 上海神经科学研究所 [3]
• 宁波材料技术与工程研... [2]
• 昆明植物研究所 [2]
• 烟台海岸带研究所 [2]
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采集方式

• OAI收割 [28]
• iSwitch采集 [1]

内容类型

• 期刊论文 [28]
• 会议论文 [1]

发表日期

• 2023 [1]
• 2022 [1]
• 2020 [2]
• 2019 [2]
• 2018 [1]
• 2017 [1]
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学科主题

• Chemistry [3]
• Chemistry,... [2]
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筛选

浏览/检索结果: 共29条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 19 作者:  Wang, Pingyuan;  Zhu, Wen-Ting;  Wang, Yajing;  Song, Shan-Shan;  Xi, Yong   |  收藏  |  浏览/下载：70/0  |  提交时间：2023/10/17 PARP1 inhibitor  Synthetic lethality  Drug resistance  Anticancer  Structure -activity relationship   BCL-2 inhibitor synergizes with PI3K delta inhibitor and overcomes FLT3 inhibitor resistance in acute myeloid leukaemia 期刊论文  OAI收割 AMERICAN JOURNAL OF CANCER RESEARCH, 2022, 卷号: 12, 期号: 8, 页码: 3829-3842 作者:  Yao, Ming-Yue;  Wang, Ya-Fang;  Zhao, Yu;  Ling, Li-Jun;  He, Ye   |  收藏  |  浏览/下载：28/0  |  提交时间：2022/12/13 Acute myeloid leukaemia  BCL-2  PI3K delta  FLT3  synergistic lethality   CRISPR-cas9: a powerful tool towards precision medicine in cancer treatment 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 5, 页码: 583-587 作者:  Xing, Hui;  Meng, Ling-hua   |  收藏  |  浏览/下载：31/0  |  提交时间：2020/07/01 precision medicine  CRISPR-cas9  drug target  biomarker  drug resistance  synergistic lethality   Enhancement of DNA damage repair potential in germ cells of Caenorhabditis elegans by a volatile signal from their irradiated partners 期刊论文  OAI收割 DNA REPAIR, 2020, 卷号: 86, 期号: 1, 页码: 9 作者:  Tang, Huangqi;  Chen, Liangwen;  Dai, Zhangyu;  Zhang, Wenjing;  Wang, Ting   |  收藏  |  浏览/下载：42/0  |  提交时间：2020/04/28 Inter-worm communication  C. elegans  Embryonic lethality  Radio-adaptive responses  DNA damage repair   Development of novel chromeno[4,3-c]pyrazol-4(2H)-one derivates containing piperazine as inhibitors of PI3K alpha 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2019, 卷号: 92 作者:  Yin, Yong;  Zhou, Yang;  Sha, Shao;  Wu, Xun;  Wang, She-Feng   |  收藏  |  浏览/下载：36/0  |  提交时间：2019/12/18 EMBRYONIC LETHALITY  PATHWAY  KINASE  PI3K  DISCOVERY  3-KINASES  SUBUNIT  GROWTH  POTENT  TARGET   Development of novel chromeno[4,3-c]pyrazol-4(2H)-one derivates containing piperazine as inhibitors of PI3K alpha 会议论文  OAI收割 作者:  Yin, Yong;  Zhou, Yang;  Sha, Shao;  Wu, Xun;  Wang, She-Feng   |  收藏  |  浏览/下载：144/0  |  提交时间：2021/12/02 EMBRYONIC LETHALITY  PATHWAY  KINASE  PI3K  DISCOVERY  3-KINASES  SUBUNIT  GROWTH  POTENT  TARGET   Lipid-Based Liquid Crystalline Nanoparticles Facilitate Cytosolic Delivery of siRNA via Structural Transformation 期刊论文  OAI收割 NANO LETTERS, 2018, 卷号: 18, 期号: 4, 页码: 2411-2419 作者:  He, Shufang;  Fan, Weiwei;  Wu, Na;  Zhu, Jingjing;  Miao, Yunqiu   |  收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08 Lipids  liquid crystalline nanoparticles  siRNA delivery  endosomal escape  synthetic lethality   Novel PARP1/2 inhibitor mefuparib hydrochloride elicits potent in vitro and in vivo anticancer activity, characteristic of high tissue distribution 期刊论文  OAI收割 ONCOTARGET, 2017, 卷号: 8, 期号: 3, 页码: 4156-4168 作者:  He, Jin-Xue;  Wang, Meng;  Huan, Xia-Juan;  Chen, Chuan-Huizi;  Song, Shan-Shan   |  收藏  |  浏览/下载：51/0  |  提交时间：2019/01/08 MPH  PARP inhibitor  homologous recombination  antitumor activity  synthetic lethality   Chemical constituents and their bioactivities from the fruits of Vitex negundo var. cannabifolia 期刊论文  OAI收割 NATURAL PRODUCT RESEARCH, 2016, 卷号: 30, 期号: 24, 页码: 2856-2860 作者:  Fang, Sheng-Tao;  Kong, Na-Na;  Yan, Bing-Fei;  Yang, Cui-Yun;  Wang, Jian-Hua 收藏  |  浏览/下载：60/0  |  提交时间：2017/03/02 Vitex negundo var. cannabifolia  chemical constituent  cytotoxicity  brine shrimp lethality   New Phragmalin-Type Limonoid Orthoesters from the Bark of Chukrasia tabularis var. velutina 期刊论文  OAI收割 HELVETICA CHIMICA ACTA, 2015, 卷号: 98, 期号: 10, 页码: 1403-1410 作者:  Liu,Wen-Xing;  Chen,Duo-Zhi;  Ding,Jia-Yin;  Hao,Xiao-Jiang;  Li,Shun-Lin 收藏  |  浏览/下载：24/0  |  提交时间：2016/01/19 Limonoids  Orthoesters  X-Ray diffraction  Brine shrimp lethality  Chukrasia tabularis