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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [3]
福建物质结构研究所 [2]
化学研究所 [1]
昆明植物研究所 [1]
长春应用化学研究所 [1]
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OAI收割 [8]
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期刊论文 [8]
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2016 [2]
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Bavachinin, as a novel natural pan-PPAR agonist, exhibits unique synergistic effects with synthetic PPAR-gamma and PPAR-alpha agonists on carbohydrate and lipid metabolism in db/db and diet-induced obese mice
期刊论文
OAI收割
DIABETOLOGIA, 2016, 卷号: 59, 期号: 6, 页码: 1276-1286
作者:
Feng, Li
;
Luo, Huan
;
Xu, Zhijian
;
Yang, Zhuo
;
Du, Guoxin
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2016/08/22
Alternative binding site
Bavachinin
Canonical ligand-binding pocket
Carbohydrate metabolism
Lipid metabolism
Pan-PPAR agonist
Synergistic effects
Bavachinin, as a novel natural pan-PPAR agonist, exhibits unique synergistic effects with synthetic PPAR-gamma and PPAR-alpha agonists on carbohydrate and lipid metabolism in db/db and diet-induced obese mice
期刊论文
OAI收割
DIABETOLOGIA, 2016, 卷号: 59, 期号: 6, 页码: 1276-1286
作者:
Feng, Li
;
Luo, Huan
;
Xu, Zhijian
;
Yang, Zhuo
;
Du, Guoxin
  |  
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2019/01/08
Alternative binding site
Bavachinin
Canonical ligand-binding pocket
Carbohydrate metabolism
Lipid metabolism
Pan-PPAR agonist
Synergistic effects
Pocket-Based Drug Design: Exploring Pocket Space
期刊论文
OAI收割
aaps journal, 2013, 卷号: 15, 期号: 1, 页码: 228-241
Zheng XL
;
Gan LF
;
Wang EK
;
Wang J
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2014/04/18
PROTEIN-LIGAND-BINDING
SMALL-MOLECULE BINDING
STRUCTURAL BASIS
TARGET FLEXIBILITY
TRANSIENT POCKETS
SITE PREDICTION
NORMAL-MODES
RAS PROTEIN
IN-SILICO
DRUGGABILITY
Structure-based Engineering of Species Selectivity in the Interaction between Urokinase and Its Receptor IMPLICATION FOR PRECLINICAL CANCER THERAPY
期刊论文
OAI收割
Journal of Biological Chemistry, 2010, 卷号: 285, 期号: 14, 页码: 10982-10992
L. Lin, H. Gardsvoll, Q. Huai, M. D. Huang and M. Ploug
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  |  
浏览/下载:65/0
  |  
提交时间:2012/11/02
cellular-binding site
plasminogen-activator
anthrax toxin
combinatorial chemistry
functional epitope
ligand-binding
deficient
mice
tumor-cells
in-vivo
vitronectin
A new drug binding subsite on human serum albumin and drug-drug interaction studied by X-ray crystallography
期刊论文
OAI收割
Journal of Structural Biology, 2008, 卷号: 162, 期号: 1, 页码: 40-49
L. L. Zhu
;
F. Yang
;
L. Q. Chen
;
E. J. Meehan and M. D. Huang
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2013/01/22
human serum albumin
3'-azido-3'-deoxythymidine
salicylic acid
drug-albumin interaction
drug-drug interaction
drug binding site
X-ray crystallography
mitochondrial azt metabolism
fatty-acid-binding
reverse-transcriptase
crystal-structure
acetylsalicylic-acid
multidrug-resistance
ligand-binding
sites
competition
plasma
Spectroscopic studies of the interaction between hypocrellin B and human serum albumin
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2006, 卷号: 14, 期号: 7, 页码: 2428-2432
作者:
Zhao, BZ
;
Song, LM
;
Liu, X
;
Xie, H
;
Zhao, JQ
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/04/09
Hypocrellins
Human Serum Albumin
Fluorescence
Ligand Binding Site
Ph-sensitive Fluorescence