机构

• 上海药物研究所 [9]
• 金属研究所 [3]
• 合肥物质科学研究院 [2]
• 南海海洋研究所 [1]
• 昆明植物研究所 [1]
• 上海生物化学与细胞生... [1]
• 更多

采集方式

• OAI收割 [19]

内容类型

• 期刊论文 [19]

发表日期

• 2023 [1]
• 2022 [1]
• 2021 [1]
• 2020 [3]
• 2019 [3]
• 2018 [1]
• 更多

学科主题

• Oncology; ... [1]
• Pharmacolo... [1]

筛选

浏览/检索结果: 共19条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Design, Synthesis, and Biological Evaluation of 2-Aminothiazole Derivatives as Novel Checkpoint Kinase 1 (CHK1) Inhibitors 期刊论文  OAI收割 CHEMMEDCHEM, 2023, 页码: 19 作者:  Deng, Minjie;  Wang, Peipei;  Long, Xiubing;  Xu, Gaoya;  Wang, Chang   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/04/10 2-aminothiazole  CHK1 inhibitors  antiproliferation  hematologic malignancies  biological activity   Effects of N-6-Methyladenosine Modification on Cancer Progression: Molecular Mechanisms and Cancer Therapy 期刊论文  OAI收割 FRONTIERS IN ONCOLOGY, 2022, 卷号: 12 作者:  Zhu, Yong-fu;  Wang, Shu-Jie   |  收藏  |  浏览/下载：28/0  |  提交时间：2022/12/23 RNA modifications  N6-methyladenosine  female malignancies  molecular mechanisms  immunotherapy   Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancies 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Jiang, Kai-long;  Tong, Le-xian;  Wang, Tao;  Wang, Han-lin;  Hu, Xiao-bei   |  收藏  |  浏览/下载：58/0  |  提交时间：2021/05/24 CHK1 inhibitors  PY34  drug sensitivity  c-Myc  hematologic malignancies   The incidence and risk factors of acute radiation-induced dermatitis in gynecologic malignancies treated with intensity-modulated radiation therapy 期刊论文  OAI收割 TRANSLATIONAL CANCER RESEARCH, 2020, 卷号: 9 作者:  Fu, Zhiqin;  Wang, Conghui;  Chen, Jianhong;  Wang, Yingchang;  Zhang, Xiang   |  收藏  |  浏览/下载：29/0  |  提交时间：2020/12/28 Gynaecological malignancies  intensity-modulated radiation therapy (IMRT)  radiation-induced dermatitis (RID)  triethanolamine   Identification and characterization of isocitrate dehydrogenase 1 (IDH1) as a functional target of marine natural product grincamycin B 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 13 作者:     |  收藏  |  浏览/下载：64/0  |  提交时间：2020/12/24 grincamycin B  marine natural product  isocitrate dehydrogenase 1  apoptosis  ER stress  intracellular ROS  Zebrafish embryos  hematological malignancies   Discovery and biological evaluation of N-(3-(7-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-4-methyl-2-oxo-2H-pyrimido[4,5-d][1,3]oxazin-1(4H)-yl)phenyl)acrylamide as potent Bruton's tyrosine kinase inhibitors 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 415-422 作者:  Lai, Meng-zhen;  Song, Pei-ran;  Dou, Dou;  Diao, Yan-yan;  Tong, Lin-jiang   |  收藏  |  浏览/下载：20/0  |  提交时间：2020/07/01 B cell receptor  Bruton's tyrosine kinase  ibrutinib  small-molecule inhibitor  B cell malignancies   Novel-targeted therapy for hematological malignancies with JAK and HDAC dual inhibitors 期刊论文  OAI收割 FUTURE MEDICINAL CHEMISTRY, 2019, 卷号: 11, 期号: 15, 页码: 1849-1852 作者:  Liang, Xuewu;  Liu, Hong;  Zhang, Yingjie   |  收藏  |  浏览/下载：19/0  |  提交时间：2020/07/01 dual inhibitors  HDAC  hematological malignancies  JAK  multiple target drugs   Discovery and Biological evaluation of pyrimido[4,5-d] pyrimidine-2,4(1H, 3H)-dione derivatives as potent Bruton's tyrosine kinase inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3390-3395 作者:  Diao, Yanyan;  Fang, Xiaoyu;  Song, Peiran;  Lai, Mengzhen;  Tong, Linjiang   |  收藏  |  浏览/下载：58/0  |  提交时间：2020/07/01 Bruton's tyrosine kinase  B-cell malignancies  Potent inhibitors  Structure-activity relationship  Cellular activities   Discovery of (R)-5-((5-(1-methyl-1H-pyrazol-4-yl)-4-(methylamino) pyrimidin-2-yl)amino)-3-(piperidin-3-yloxy)picolinonitrile, a novel CHK1 inhibitor for hematologic malignancies 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 173, 页码: 44-62 作者:  Tong, Lexian;  Song, Pinrao;  Jiang, Kailong;  Xu, Lei;  Jin, Tingting   |  收藏  |  浏览/下载：28/0  |  提交时间：2020/07/01 CHK1 kinase inhibitor  Selectivity  Monotherapy  Hematologic malignancies   Molecular modelling studies on cinnoline-based BTK inhibitors using docking and structure-based 3D-QSAR 期刊论文  OAI收割 SAR AND QSAR IN ENVIRONMENTAL RESEARCH, 2018, 卷号: 29, 期号: 11, 页码: 847-873 作者:  Li, R.;  Du, Y.;  Shen, J.   |  收藏  |  浏览/下载：47/0  |  提交时间：2019/01/08 BTK inhibitors  B-cell malignancies  molecule docking  3D-QSAR  CoMFA  CoMSIA