机构

• 上海药物研究所 [21]
• 水生生物研究所 [13]
• 上海生物化学与细胞... [11]
• 植物研究所 [10]
• 近代物理研究所 [10]
• 上海神经科学研究所 [9]
• 更多

采集方式

• OAI收割 [137]
• iSwitch采集 [14]

内容类型

• 期刊论文 [148]
• 学位论文 [2]
• 会议论文 [1]

发表日期

• 2022 [3]
• 2021 [7]
• 2020 [11]
• 2019 [11]
• 2018 [6]
• 2017 [13]
• 更多

学科主题

• Biochemis... [12]
• Plant Sci... [10]
• Biochemist... [4]
• Biophysics [3]
• Genetics &... [3]
• Multidisci... [3]
• 更多

筛选

浏览/检索结果: 共151条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Integrative study of lung cancer adeno-to-squamous transition in EGFR TKI resistance identifies RAPGEF3 as a therapeutic target 期刊论文  OAI收割 NATIONAL SCIENCE REVIEW, 2024, 卷号: 11, 期号: 12, 页码: 20 作者:  Wang, Hua;  Tang, Shijie;  Wu, Qibiao;  He, Yayi;  Zhu, Weikang   |  收藏  |  浏览/下载：14/0  |  提交时间：2025/02/28 EGFR-mutant lung cancer  adeno-to-squamous transition  tyrosine kinase inhibitor resistance  transcription factor network  RAPGEF3   2022年全球新冠肺炎疫苗和药物研究热点回眸 期刊论文  OAI收割 科技导报, 2023, 卷号: 41, 期号: 1, 页码: 136 作者:  刘丽丽;  黄瑶庆;  高月红;  陆彩女;  王春丽   |  收藏  |  浏览/下载：22/0  |  提交时间：2023/05/22 COVID-19  virus mutant  vaccines  neutralizing antibody  small molecule antiviral drugs  新冠肺炎  病毒变异株  疫苗  中和抗体  小分子抗病毒药   Design, synthesis and pharmacological evaluation of new PARP1 inhibitors by merging pharmacophores of olaparib and the natural product alantolactone 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 240, 页码: 114574 作者:  Kayumov, Muzaffar;  Jia, Li;  Pardaev, Azizbek;  Song, Shan-Shan;  Mirzaakhmedov, Sharafitdin   |  收藏  |  浏览/下载：34/0  |  提交时间：2024/03/21 PARP1  Olaparib  Alantolactone  Syntheticlethality  BRCA1/2mutant   Discovery of a Potent and Selective Degrader for USP7 期刊论文  OAI收割 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022, 卷号: 61, 期号: 33, 页码: e202204395 作者:  Pei, Yuan;  Fu, Jingfeng;  Shi, Yunkai;  Zhang, Mengmeng;  Luo, Guanghao   |  收藏  |  浏览/下载：27/0  |  提交时间：2024/03/21 Apoptotic Pathway  Mutant p53  p53 Mutant Cancer Cells  PROTAC  USP7 Degrader   Scaling-up and proteomic analysis reveals photosynthetic and metabolic insights toward prolonged H2 photoproduction in Chlamydomonas hpm91 mutant lacking proton gradient regulation 5 (PGR5) 期刊论文  OAI收割 PHOTOSYNTHESIS RESEARCH, 2022, 卷号: 154, 期号: 3, 页码: 397-411 作者:  Liu, Peng;  Ye, De-Min;  Chen, Mei;  Zhang, Jin;  Huang, Xia-He   |  收藏  |  浏览/下载：23/0  |  提交时间：2024/03/07 C. reinhardtii  hpm91 mutant  Scale-up H-2 production  ROS  Quantitative proteomics  hpm91-derived mutant   CRISPR Cas9-Mediated Selective Isothermal Amplification for Sensitive Detection of Rare Mutant Alleles 期刊论文  OAI收割 CLINICAL CHEMISTRY, 2021, 卷号: 67 作者:  Chen, Junman;  Qiu, Tian;  Mauk, Michael G.;  Fan, Yaguang;  Jiang, Yong   |  收藏  |  浏览/下载：48/0  |  提交时间：2022/01/10 mutant allele enrichment  programmable endonuclease  liquid biopsy  mutation detection  point-of-care testing  isothermal nucleic acids amplification   Comparative transcriptome analysis reveals candidate genes for leaf color formation in a thermo-sensitive leaf-color mutant generated by carbon-ion beam in green wandering Jew (Tradescantia fluminensis) 期刊论文  OAI收割 SCIENTIA HORTICULTURAE, 2021, 卷号: 288, 页码: 17 作者:  Liu, Ruiyuan;  Dong, Xicun;  Zhang, Miaomiao;  Qu, Ying;  Jin, Wenjie   |  收藏  |  浏览/下载：55/0  |  提交时间：2021/12/08 Green wandering Jew  Leaf-color mutant  Temperature  Transcriptome  Flavonoids  Photosynthesis   KRAS-Mutant Non-Small Cell Lung Cancer: An Emerging Promisingly Treatable Subgroup 期刊论文  OAI收割 FRONTIERS IN ONCOLOGY, 2021, 卷号: 11 作者:  Xie, Mingying;  Xu, Xiaoling;  Fan, Yun   |  收藏  |  浏览/下载：45/0  |  提交时间：2021/06/15 KRAS-mutant  NSCLC  targeted therapy  immunotherapy  AMG510  MRTX849   Third-generation EGFR inhibitor HS-10296 in combination with famitinib, a multi-targeted tyrosine kinase inhibitor, exerts synergistic antitumor effects through enhanced inhibition of downstream signaling in EGFR-mutant non-small cell lung cancer cells 期刊论文  OAI收割 THORACIC CANCER, 2021, 页码: 9 作者:  Zhang, Mi;  Quan, Haitian;  Fu, Li;  Li, Yun   |  收藏  |  浏览/下载：65/0  |  提交时间：2021/05/24 EGFR‐  mutant non‐  small cell lung cancer  famitinib  HS‐  10296  multi‐  targeted tyrosine kinase inhibitor  third‐  generation EGFR inhibitor   Gossypol, a novel modulator of VCP, induces autophagic degradation of mutant huntingtin by promoting the formation of VCP/p97-LC3-mHTT complex 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2021, 卷号: 42, 期号: 10, 页码: 1556-1566 作者:  Li, Xiao-jing;  Zhang, Yuan-yuan;  Fu, Yu-hua;  Zhang, Hao;  Li, He-xuan   |  收藏  |  浏览/下载：25/0  |  提交时间：2024/03/21 Huntington disease  mutant huntingtin protein  gossypol acetate  VCP  LC3  autophagic degradation  drug reposition