中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [9]
武汉病毒研究所 [2]
成都生物研究所 [1]
昆明植物研究所 [1]
采集方式
OAI收割 [11]
iSwitch采集 [2]
内容类型
期刊论文 [13]
发表日期
2023 [1]
2019 [1]
2018 [1]
2016 [2]
2015 [2]
2014 [1]
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学科主题
Pharmacolo... [2]
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2022年全球新冠肺炎疫苗和药物研究热点回眸
期刊论文
OAI收割
科技导报, 2023, 卷号: 41, 期号: 1, 页码: 136
作者:
刘丽丽
;
黄瑶庆
;
高月红
;
陆彩女
;
王春丽
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/05/22
COVID-19
virus mutant
vaccines
neutralizing antibody
small molecule antiviral drugs
新冠肺炎
病毒变异株
疫苗
中和抗体
小分子抗病毒药
Treatment of Chronic Hepatitis B Virus Infection Using Small Molecule Modulators of Nucleocapsid Assembly: Recent Advances and Perspectives
期刊论文
OAI收割
ACS INFECTIOUS DISEASES, 2019, 卷号: 5, 期号: 5, 页码: 713-724
作者:
Yang, Li
;
Liu, Feifei
;
Tong, Xiankun
;
Hoffmann, Daniel
;
Zuo, Jianping
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
hepatitis B virus
HBV core protein
HBcAg
capsid assembly
capsid assembly modulators (CAMs)
antiviral therapy
clinical trials
Small Molecule Inhibitors of Hepatitis B Virus Nucleocapsid Assembly: A New Approach to Treat Chronic HBV Infection
期刊论文
OAI收割
CURRENT MEDICINAL CHEMISTRY, 2018, 卷号: 25, 期号: 7, 页码: 802-813
作者:
Yang, Li
;
Lu, Mengji
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
Hepatitis B virus
core protein
capsid assembly
capsid assembly modulator
misassembly
antiviral therapy
Identification and biochemical characterization of DC07090 as a novel potent small molecule inhibitor against human enterovirus 71 3C protease by structure-based virtual screening
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 124, 页码: 981-991
作者:
Ma, Guang-Hui
;
Ye, Yan
;
Zhang, Dan
;
Xu, Xin
;
Si, Pei
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
HFMD
EV71 3C(Pro)
Non-peptidyl inhibitor
Virtual screening
Small-Molecule Therapeutics for Ebola Virus (EBOV) Disease Treatment
期刊论文
OAI收割
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2016, 期号: 1, 页码: 8-16
作者:
Izawa, Kunisuke
;
Luis Acena, Jose
;
Wang, Jiang
;
Soloshonok, Vadim A.
;
Liu, Hong
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
Synthetic methods
Medicinal chemistry
Drug design
Antiviral agents
Policresulen, a novel NS2B/NS3 protease inhibitor, effectively inhibits the replication of DENV2 virus in BHK-21 cells
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2015, 卷号: 36, 期号: 9, 页码: 1126-1136
作者:
Wu, Deng-wei
;
Mao, Fei
;
Ye, Yan
;
Li, Jian
;
Xu, Chuan-lian
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
Dengue virus
antiviral drug
NS2B/NS3 protease
policresulen
molecular docking
molecular modeling
policresulenanovelns2bns3proteaseinhibitoreffectivelyinhibitsthereplicationofdenv2virusinbhk21cells
期刊论文
OAI收割
actapharmacologicasinica, 2015, 卷号: 36, 期号: 9, 页码: 1126
作者:
Wu Dengwei
;
Mao Fei
;
Ye Yan
;
Li Jian
;
Xu Chuanlian
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/07/01
SMALL-MOLECULE INHIBITORS
STRUCTURE-BASED DISCOVERY
DRUG-LIKE MOLECULES
DENGUE VIRUS
SERINE-PROTEASE
NS3 PROTEASE
PEPTIDE INHIBITORS
NS2B-NS3 PROTEASE
ACCURATE DOCKING
IN-VITRO
Dengue virus
antiviral drug
NS2B/NS3 protease
policresulen
molecular docking
molecular modeling
Self-Organizing Maps for the Classification of Gallic Acylate Polyphenols as HSV-1 Inhibitors
期刊论文
OAI收割
MEDICINAL CHEMISTRY, 2014, 卷号: 10, 期号: 4, 页码: 388-401
作者:
Qiu, Xianxiu
;
Zhong, Meigong
;
Xiang, Yangfei
;
Qu, Chang
;
Pei, Ying
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2014/06/23
Artificial neural network
counterpropagation neural networks
gallic acylate polyphenol
herpes simplex viruses
self-organizing maps
structure-activity relationship
Identifying Chemicals with Potential Therapy of HIV Based on Protein-Protein and Protein-Chemical Interaction Network
期刊论文
OAI收割
PLOS ONE, 2013, 卷号: 8, 期号: 6
作者:
Li, Bi-Qing
;
Niu, Bing
;
Chen, Lei
;
Wei, Ze-Jun
;
Huang, Tao
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/01/08
Identification of Small Molecule Activators of the Janus Kinase/Signal Transducer and Activator of Transcription Pathway Using a Cell-Based Screen
期刊论文
OAI收割
BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2012, 卷号: 35, 期号: 1, 页码: 65-71
Tai, Zheng Fu
;
Zhang, Guo Lin
;
Wang, Fei
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2013/07/03
interferon
Janus kinase: signal transducer and activator of transcription
emodin
quercetin
luteolin