中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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Strategic Amino Acid Mutations in CPD Cleavage Motif: Impacts on Hydrolysis and C-Terminal Modification Efficiency
期刊论文
OAI收割
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2025, 卷号: 41, 期号: 3, 页码: 592-600
作者:
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收藏
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浏览/下载:2/0
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提交时间:2025/06/23
Protein engineering
C-Terminal modification
Cysteine protease domain
Self-cleavage tag
AlphaFold2
Design, synthesis, and activity evaluation of indole derivatives as potential stabilizers for p53 Y220C
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 121, 页码: 9
作者:
Li, Linquan
;
Gu, Xi
;
Meng, Jingyi
;
Wen, Yiming
;
Yi, Jing
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收藏
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浏览/下载:1/0
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提交时间:2025/05/27
p53 Y220C
Synthesis
Structural modification
Drug design
Nanobody-based drug delivery systems for cancer therapy
期刊论文
OAI收割
JOURNAL OF CONTROLLED RELEASE, 2025, 卷号: 381, 页码: 29
作者:
Liu, Lin
;
Tu, Bin
;
Sun, Yao
;
Liao, Lingling
;
Lu, Xiaoling
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收藏
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浏览/下载:0/0
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提交时间:2025/04/24
Nanobody
VHH
Cancer therapy
Targeted drug delivery systems
Nanobody modification
Development of 3-arylaminothiophenic-2-carboxylic acid derivatives as new FTO inhibitors showing potent antileukemia activities
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 289, 页码: 17
作者:
Zhang, Deyan
;
Liu, Lu
;
Li, Ming
;
Hu, Xinyi
;
Zhang, Xi
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收藏
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浏览/下载:0/0
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提交时间:2025/04/24
RNA modification
N 6-methyladenosine
Demethylase FTO
Structure-activity relationship
Antileukemia
Preparation of novel thiolated chitosan with significant antioxidant activity
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2025, 卷号: 308, 页码: 15
作者:
Han, Xiangru
;
Tian, Liguang
;
Chen, Qiuhong
;
Wang, Linqing
;
Mi, Yingqi
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收藏
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浏览/下载:2/0
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提交时间:2025/06/09
Antioxidant activity
Chemical modification
Chitosan derivative
Thiol group
Enhancement on durability of cohesive soil by solidifying with modified guar gum
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2025, 卷号: 309, 页码: 16
作者:
Liu, Yang
;
Du, Changbo
;
Yi, Fu
;
Li, Jiangshan
;
Li, Min
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收藏
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浏览/下载:0/0
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提交时间:2025/06/27
Biopolymer modification
Dry-wet cycle
Freeze-thaw cycle
Unconfined compressive strength (UCS)
Microstructure
Oxalate modification enabled advanced phosphate removal of nZVI: In Situ formed surface ternary complex and altered multi-stage adsorption process
期刊论文
OAI收割
JOURNAL OF ENVIRONMENTAL SCIENCES, 2025, 卷号: 149, 页码: 79-87
作者:
Cao, Shiyu
;
Li, Jiangshan
;
Shi, Yanbiao
;
Guo, Furong
;
Gao, Tingjuan
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收藏
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浏览/下载:0/0
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提交时间:2025/06/27
Oxalate modification
Advanced phosphate removal
Surface ternary complex
Multi -stage adsorption
Nano zero-valent iron (nZVI)
Design, synthesis and biological evaluation of Alisol B derivatives for potential treatment of non-alcoholic steatohepatitis
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 155, 页码: 15
作者:
Yu, Nai-Rong
;
Huang, Suling
;
Deng, Zhen-Tao
;
Wang, Jiayue
;
Shen, Yu
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收藏
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浏览/下载:16/0
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提交时间:2025/04/01
Non-alcoholic steatohepatitis (NASH)
Alisol B
Structural modification
Structure-activity relationship
HFD+CCl4-induced NASH mice model
Strength development of dredged sediment stabilized with nano-modified sulphoaluminate cement
期刊论文
OAI收割
SOILS AND FOUNDATIONS, 2025, 卷号: 65, 期号: 1, 页码: 16
作者:
Lang, Lei
;
Xue, Dan-Xuan
;
Dong, Meng
;
Zhang, Wei
;
Li, Jiang-Shan
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收藏
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浏览/下载:0/0
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提交时间:2025/06/27
Dredged sediment stabilization
Sulphoaluminate cement
Nano-modification
Strength development
Micro-mechanism
The role of dsRNA A-to-I editing catalyzed by ADAR family enzymes in the pathogeneses
期刊论文
OAI收割
RNA BIOLOGY, 2024, 卷号: 21, 期号: 1, 页码: 52-69
作者:
Liu, Wanqing
;
Wu, Yufan
;
Zhang, Tong
;
Sun, Xiaobo
;
Guo, Dean
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收藏
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浏览/下载:8/0
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提交时间:2024/11/26
Double Stranded RNA (dsRNA) Adenosine-to-Inosine (A-to-I) Editing
Adenosine Deaminases (ADAR) Enzyme
Pathogenesis
RNA Modification
Tumorigenicity