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Chinese Academy of Sciences Institutional Repositories Grid
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长春应用化学研究所 [85]
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Discovery of novel covalent stabilizers for p53 Y220C using structure-based drug discovery methods
期刊论文
OAI收割
MOLECULAR DIVERSITY, 2025, 页码: 14
作者:
Wen, Yiming
;
Xu, Peijia
;
Chen, Yijie
;
Meng, Jingyi
;
Zheng, Mingyue
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/04/01
p53 Y220C
Covalent stabilizer
Virtual screening
Molecular dynamics
DNA binding
Structure-activity relationship
Cancer therapy
Characterization of the Unarmored Dinoflagellate
Karlodinium decipiens
(Dinophyceae) from Jiaozhou Bay, China
期刊论文
OAI收割
DIVERSITY-BASEL, 2024, 卷号: 16, 期号: 8, 页码: 16
作者:
Yao, Jialin
;
Fan, Yingyi
;
Chen, Qiantong
;
Chen, Xinxin
;
Deng, Yunyan
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/12/20
Karlodinium decipiens
apical structure complex
molecular phylogeny
morphology
amphiesmal vesicle
toxicity
Design, synthesis and structure-activity relationship of 1,8-naphthalimide derivatives as highly potent hCYP1B1 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 107, 页码: 8
作者:
Wei, Yueyue
;
Xiong, Yuan
;
Liao, Qingyi
;
Yang, Ya
;
Tian, Tian
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/07/12
8-naphthalimide
Structure -activity relationships (SAR)
Paclitaxel (PTX) resistance
Molecular docking
Evolution of aromatic structure and nanopores in shale kerogen by using in-situ HRTEM and in-situ FT-IR experiment
期刊论文
OAI收割
FUEL, 2024, 卷号: 359, 页码: 13
作者:
Su, Chi
;
Liu, Yu
;
Yang, Yueheng
;
Gao, Tengwei
;
Qi, Tianyang
  |  
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2024/01/22
In-situ HRTEM
Kerogen
Molecular structure
Aromatic clusters
Nanopores
Platanosides from Platanus x acerifolia: New molecules, SAR, and target validation of a strong lead for drug-resistant bacterial infections and the associated sepsis
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9
作者:
Wu, Xi-Ying
;
Zhao, Ze-Yu
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2024/03/06
Platanus x acerifolia
Platanosides
Molecular ion networking (MoIN)
Antibacterial
Staphylococcus aureus
Enterococcus faecium
Structure -activity relationship (SAR)
Molecular docking
Target validation
Morphological and Molecular Characterization of the Unarmored Dinoflagellate
Gymnodinium trapeziforme
(Dinophyceae) from Jiaozhou Bay, China
期刊论文
OAI收割
DIVERSITY-BASEL, 2023, 卷号: 15, 期号: 12, 页码: 12
作者:
Gao, Menghan
;
Hu, Zhangxi
;
Luo, Zhaohe
;
Deng, Yunyan
;
Shang, Lixia
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/12/23
Gymnodinium trapeziforme
apical structure complex
molecular phylogeny
morphology
Impact of long-term ultrasound treatment on structural and physicochemical properties of starches differing in granule size
期刊论文
OAI收割
CARBOHYDRATE POLYMERS, 2023, 卷号: 320, 页码: 14
作者:
Wei, Yiyun
;
Li, Guantian
;
Zhu, Fan
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/12/13
Starch modification
Starch structure
Physicochemical property
Granular structure
Rheological property
Molecular structure
Quinoa starch
Small granule starch
Corn starch
The in vivo drug delivery pattern of the organelle-targeting small molecules
期刊论文
OAI收割
ADVANCED DRUG DELIVERY REVIEWS, 2023, 卷号: 200, 页码: 14
作者:
Fang, Zhao
;
Chen, Hao
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/10/17
Organelle-targeting
In vivo imaging
Small molecular probe
Biodistribution
Subcellular structure
Human disease
Ab initio Molecular Dynamics Study of Local Atomic Structure Evolution of U-Zr Alloy Melts upon Solidification
期刊论文
OAI收割
ACTA METALLURGICA SINICA-ENGLISH LETTERS, 2023, 页码: 10
作者:
Liu, Mingfeng
;
Wang, Jiantao
;
Shi, Yongpeng
;
Zhu, Heyu
;
Sun, Yan
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/01/07
Local atomic structure
Molecular dynamics
Solidification
U-Zr alloy melts
Molecular Imaging Reveals Two Distinct Mixing States of PM2.5 Particles Sampled in a Typical Beijing Winter Pollution Case
期刊论文
OAI收割
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2023, 卷号: N/A
作者:
Li, Ye
;
Zhou, Yadong
;
Guo, Wenxiao
;
Zhang, Xin
;
Huang, Ye
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/01/04
PM2
5
mixing state
3-D molecular imaging
surface chemistry
core-shell structure