中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [41]
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上海生物化学与细胞... [26]
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期刊论文 [324]
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Recent advances in targeted degradation in the RAS pathway
期刊论文
OAI收割
FUTURE MEDICINAL CHEMISTRY, 2025, 卷号: 17, 期号: 6, 页码: 693-708
作者:
Ge, Zhiming
;
Fan, Zisheng
;
He, Wei
;
Zhou, Guizhen
;
Zhou, Yidi
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/04/24
RAS
cancer
mutation
degrader
PROTAC
Potential roles of the sirtuins in promoting longevity for larger
Argopecten
scallops
期刊论文
OAI收割
MARINE LIFE SCIENCE & TECHNOLOGY, 2025, 页码: 18
作者:
Zhao, Yang
;
Ning, Junhao
;
Wang, Yuan
;
Liu, Guilong
;
Xu, Xin
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/05/09
Scallops
SIRTs
Genetic mutation
Evolution
Nutrient restriction
Longevity
IHCH9033, a novel class I HDAC inhibitor, synergizes with FLT3 inhibitor and rescues quizartinib resistance in FLT3-ITD AML via enhancing DNA damage response
期刊论文
OAI收割
EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2025, 卷号: 14, 期号: 1, 页码: 19
作者:
Yao, Mingyue
;
Yan, Wenzhong
;
Wang, Yafang
;
Zhao, Yu
;
Xu, Xiaowei
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/04/01
Acute myeloid leukemia
HDAC inhibitor
FLT3-ITD mutation
DNA damage response
Synergistic effect
Drug resistance
Analysis of Deformation and Ultimate Bearing Capacity of the Arch Dam of the Dagangshan Hydropower Station
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF GEOMECHANICS, 2025, 卷号: 25, 期号: 2, 页码: 17
作者:
Guo, Deyu
;
Zhang, Lewen
;
Wu, Jing
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/06/27
Dagangshan Hydropower Station
High arch dam
Measured deformation behavior
Ultimate bearing capacity
Cusp mutation model
Numerical simulation
MGAT4A/Galectin9-Driven
N
-Glycosylation Aberration as a Promoting Mechanism for Poor Prognosis of Endometrial Cancer with
TP53
Mutation
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 19
作者:
Zhu, Zhen
;
Sun, Jingya
;
Xu, Weiqing
;
Zeng, Qinghe
;
Feng, Hanyi
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/12/11
endometrial cancer
glucose metabolism
MGAT4A
N
-glycosylation
TP53
mutation
An overview of the functions and mechanisms of APOBEC3A in tumorigenesis
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 11, 页码: 4637-4648
作者:
Yang, Yuqi
;
Liu, Nan
;
Gong, Likun
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/01/06
Tumor-associated viruses
Tumor microenvironment
APOBEC3A
Deaminase
Mutation
DNA damage
Tumorigenesis
Tumor-associated viruses
Macrophage
Tumor microenvironment
Aberrant copper metabolism and hepatic inflammation cause neurological manifestations in a mouse model of Wilson's disease
期刊论文
OAI收割
JOURNAL OF NEUROINFLAMMATION, 2024, 卷号: 21
作者:
Dong, Jianjian
;
Xiang, Guanghai
;
Xia, Xiaoxue
;
Xu, Lewen
;
Wen, Peihua
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/11/20
Wilson's disease
ATP7B gene
R778L point mutation
Hepatic inflammation
Neurological manifestations
CRISPR/Cas9
A synonymous mutation of rs1137070 cause the mice
Maoa
gene transcription and translation to decrease
期刊论文
OAI收割
FRONTIERS IN MOLECULAR NEUROSCIENCE, 2024, 卷号: 17
作者:
Li, Kai Xin
;
Fan, Lei
;
Wang, Hongjuan
;
Tian, Yushan
;
Zhang, Sen
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/11/20
Maoa EcoRV polymorphism
Monoamine oxidase A
synonymous mutation
rs1137070
mouse model
BRAF-induced
EHF
Expression Affects
TERT
in Aggressive Papillary Thyroid Cancer
期刊论文
OAI收割
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2024
作者:
Xu, Yiyi
;
Gao, Jiwei
;
Wang, Na
;
Zedenius, Jan
;
Nilsson, Inga-Lena
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/11/20
EHF
TERT promoter mutation
BRAF(V600E)
thyroid carcinoma
prognosis
Development of DNA Insertion-specific Markers Based on the Intron Region of
Oplegnathus punctatus itih4b
for Genetic Sex Identification
期刊论文
OAI收割
MARINE BIOTECHNOLOGY, 2024, 页码: 9
作者:
Ma, Yuting
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/12/20
Oplegnathus punctatus
Sex molecular marker
Genetic sex identification
itih4b
Intron mutation