中国科学院机构知识库网格系统: 检索

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	Structure-based design of a novel inhibitor of the ZIKA virus NS2B/ NS3 protease 期刊论文 OAI收割 BIOORGANIC CHEMISTRY, 2022, 卷号: 128, 页码: 7 作者: Xiong, Yanchao; Cheng, Fei; Zhang, Junyi; Su, Haixia; Hu, Hangchen \| 收藏 \| 浏览/下载：37/0 \| 提交时间：2022/11/11 Zika virus Fragment -based hit screening Protein -inhibitor interactions NS2B NS3 protease Crystal structure
	Uncoupling of protease trans-cleavage and helicase activities in pestivirus ns3 期刊论文 iSwitch采集 Journal of virology, 2017, 卷号: 91, 期号: 21, 页码: 19 作者: Zheng, Fengwei; Lu, Guoliang; Li, Ling; Gong, Peng; Pan, Zishu 收藏 \| 浏览/下载：58/0 \| 提交时间：2019/05/08 Pestivirus Ns3 Protease Helicase Crystal structure
	The Second-generation of Highly Potent Hepatitis C Virus (HCV) NS3/4A Protease Inhibitors: Evolutionary Design Based on Tailor-made Amino Acids, Synthesis and Major Features of Bio-activity 期刊论文 OAI收割 CURRENT PHARMACEUTICAL DESIGN, 2017, 卷号: 23, 期号: 30, 页码: 4493-4554 作者: Wang, Shuni; Wang, Yibing; Wang, Jiang; Sato, Tatsunori; Izawa, Kunisuke \| 收藏 \| 浏览/下载：49/0 \| 提交时间：2019/01/08 Hepatitis C virus (HCV) pandemic direct-acting antiviral agents (DAAs) NS3/4A protease inhibitor tailor-made amino acids structure-activity relationship (SAR) asymmetric synthesis ring-closing metathesis (RCM)
	Policresulen, a novel NS2B/NS3 protease inhibitor, effectively inhibits the replication of DENV2 virus in BHK-21 cells 期刊论文 OAI收割 ACTA PHARMACOLOGICA SINICA, 2015, 卷号: 36, 期号: 9, 页码: 1126-1136 作者: Wu, Deng-wei; Mao, Fei; Ye, Yan; Li, Jian; Xu, Chuan-lian \| 收藏 \| 浏览/下载：30/0 \| 提交时间：2019/01/08 Dengue virus antiviral drug NS2B/NS3 protease policresulen molecular docking molecular modeling
	policresulenanovelns2bns3proteaseinhibitoreffectivelyinhibitsthereplicationofdenv2virusinbhk21cells 期刊论文 OAI收割 actapharmacologicasinica, 2015, 卷号: 36, 期号: 9, 页码: 1126 作者: Wu Dengwei; Mao Fei; Ye Yan; Li Jian; Xu Chuanlian \| 收藏 \| 浏览/下载：54/0 \| 提交时间：2020/07/01 SMALL-MOLECULE INHIBITORS STRUCTURE-BASED DISCOVERY DRUG-LIKE MOLECULES DENGUE VIRUS SERINE-PROTEASE NS3 PROTEASE PEPTIDE INHIBITORS NS2B-NS3 PROTEASE ACCURATE DOCKING IN-VITRO Dengue virus antiviral drug NS2B/NS3 protease policresulen molecular docking molecular modeling
	Discovering novel anti-HCV compounds with inhibitory activities toward HCV NS3/4A protease 期刊论文 OAI收割 ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 8, 页码: 1074-1081 作者: Yu, Ye; Jing, Jing-feng; Tong, Xian-kun; He, Pei-lan; Li, Yuan-chao \| 收藏 \| 浏览/下载：24/0 \| 提交时间：2019/01/08 hepatitis C virus NS3/4A protease secreted embryonic alkaline phosphatase (Seap) 2,4-diaminoquinazoline carboxamide telaprevir
	discoveringnovelantihcvcompoundswithinhibitoryactivitiestowardhcvns34aprotease 期刊论文 OAI收割 actapharmacologicasinica, 2014, 卷号: 35, 期号: 8, 页码: 1074 作者: Yu Ye; Jing Jingfeng; Tong Xiankun; He Peilan; Li Yuanchao \| 收藏 \| 浏览/下载：20/0 \| 提交时间：2020/07/01 HEPATITIS-C VIRUS PLUS RIBAVIRIN REPLICATION TELAPREVIR POTENT EPIDEMIOLOGY BOCEPREVIR hepatitis C virus NS3/4A protease secreted embryonic alkaline phosphatase (Seap) 2,4-diaminoquinazoline carboxamide telaprevir
	Identification of Novel Small Molecules as Inhibitors of Hepatitis C Virus by Structure-Based Virtual Screening 期刊论文 OAI收割 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2013, 卷号: 14, 期号: 11, 页码: 22845-22856 作者: Li, Jing; Liu, Xian; Li, Shanshan; Wang, Yulan; Zhou, Nannan \| 收藏 \| 浏览/下载：24/0 \| 提交时间：2019/01/08 hepatitis C virus (HCV) NS3 NS4A serine protease structure-based drug design (SBDD) virtual screening
	Biological characteristics of dengue virus and potential targets for drug design 期刊论文 OAI收割 ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2008, 卷号: 40, 期号: 2, 页码: 91-101 作者: Qi, RF; Zhang, L; Chi, CW 收藏 \| 浏览/下载：18/0 \| 提交时间：2015/07/22 dengue virus NS3 protease polyprotein processing drug target