中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共59条,第1-10条 帮助

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One stone two birds: Introducing piperazine into a series of nucleoside derivatives as potent and selective PRMT5 inhibitors 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 18
作者:  
Li, Huaxuan;  Yang, Hong;  Liu, Li;  Zheng, Jiahong;  Shi, Qiongyu
  |  收藏  |  浏览/下载:15/0  |  提交时间:2024/12/11
Structure-based discovery of a new series of nucleoside-derived ring-opening PRMT5 inhibitors 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 267, 页码: 19
作者:  
Chen, Yuting
  |  收藏  |  浏览/下载:11/0  |  提交时间:2024/05/07
Structure-activity relationship study of a series of nucleoside derivatives bearing sulfonamide scaffold as potent and selective PRMT5 inhibitors 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 130, 页码: 20
作者:  
Chen, Yuting;  Shi, Qiongyu;  Yang, Hong;  Li, Jiayi;  Zhou, Kaixin
  |  收藏  |  浏览/下载:35/0  |  提交时间:2023/04/10
Xanthine dehydrogenase rewires metabolism and the survival of nutrient deprived lung adenocarcinoma cells by facilitating UPR and autophagic degradation 期刊论文  OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2023, 卷号: 19, 期号: 3, 页码: 772-788
作者:  
Chen, Man-man;  Guo, Wei;  Chen, Si-meng;  Guo, Xiao-zhen;  Xu, Lan
  |  收藏  |  浏览/下载:18/0  |  提交时间:2024/03/27
Development and validation of an LC-MS/MS method for simultaneous determination of remdesivir and its hydrolyzed metabolite and nucleoside, and its application in a pharmacokinetic study of normal and diabetic nephropathy mice 期刊论文  OAI收割
BIOMEDICAL CHROMATOGRAPHY, 2022, 页码: 10
作者:  
Yuan, Meng;  Hu, Wenjuan;  Feng, Yingying;  Tong, Yue;  Wang, Xin
  |  收藏  |  浏览/下载:33/0  |  提交时间:2022/06/15
Safety, tolerability, and pharmacokinetics of VV116, an oral nucleoside analog against SARS-CoV-2, in Chinese healthy subjects 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 9
作者:  
Qian, Hong-jie;  Wang, Yu;  Zhang, Meng-qi;  Xie, Yuan-chao;  Wu, Qing-qing
  |  收藏  |  浏览/下载:58/0  |  提交时间:2022/06/15
Chromatographic performance of zidovudine imprinted polymers coated silica stationary phases 期刊论文  OAI收割
TALANTA, 2022, 卷号: 239, 页码: 8
作者:  
Song, Zhihua;  Song, Yanqin;  Wang, Yinghao;  Liu, Jinqiu;  Wang, Yumeng
  |  收藏  |  浏览/下载:36/0  |  提交时间:2022/08/13
Chromatographic performance of zidovudine imprinted polymers coated silica stationary phases 期刊论文  OAI收割
TALANTA, 2022, 卷号: 239, 页码: 8
作者:  
Song, Zhihua;  Song, Yanqin
  |  收藏  |  浏览/下载:5/0  |  提交时间:2024/11/15
Synthesis and antiviral activity of 2 '-deoxy-6 '-substituted carbocyclic nucleosides 期刊论文  OAI收割
CHEMICAL BIOLOGY & DRUG DESIGN, 2021, 页码: 12
作者:  
Xue, Haitao;  Guo, Shuang;  Hu, Tianwen;  Wei, Daibao;  Xie, Yuanchao
  |  收藏  |  浏览/下载:54/0  |  提交时间:2022/01/18
Significant Inhibition of Porcine Epidemic Diarrhea Virus In Vitro by Remdesivir, Its Parent Nucleoside and beta-d-N-4-hydroxycytidine 期刊论文  OAI收割
VIROLOGICA SINICA, 2021, 页码: 9
作者:  
Xie, Yuanchao;  Guo, Xiaozhen;  Hu, Tianwen;  Wei, Daibao;  Ma, Xiuli
  |  收藏  |  浏览/下载:45/0  |  提交时间:2021/05/24