中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共239条,第1-10条 帮助

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Olmesartan prevents cardiac rupture in mice with myocardial infarction by modulating growth differentiation factor 15 and P53 期刊论文  OAI收割
出版物, 3111, 期号: 0, 页码: 1-37
作者:  
Baihe Chen;  Di Lu;  Yujuan Fu;  Jingwen Zhang;  Xiaobo Huang
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Withanolides from Physalis angulata as Potent Antimelanoma Agents: Activation of the p53 Pathway In Vitro and In Vivo 期刊论文  OAI收割
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2026, 卷号: 74, 期号: 6, 页码: 5237-5255
作者:  
Hu, Bintao;  Li, Han;  Tang, Chunping;  Ke, Chang-Qiang;  Ding, Jian
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Targeting p53 activation: Recent therapeutic advances in cancer and diabetic macular edema 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 297, 页码: 20
作者:  
Wang, Zhiyi;  Zhang, Shijie;  Irakoze, Loica Melita;  Zhao, Yujun
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A network pharmacology approach and experimental validation to investigate the protection mechanism of Ganoderma lucidum (Leyss. ex Fr.) Karst spore for acute kidney injury through induction of apoptosis via p53/ Caspase 3 signaling pathway 期刊论文  OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2025, 卷号: 351, 页码: 12
作者:  
Zhou, Yue;  Zhang, Baowen;  Wang, Xiaodan;  Liu, Xiaoqin;  Zhao, Jinna
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Design, synthesis, and activity evaluation of indole derivatives as potential stabilizers for p53 Y220C 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 121, 页码: 9
作者:  
Li, Linquan;  Gu, Xi;  Meng, Jingyi;  Wen, Yiming;  Yi, Jing
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Discovery of novel covalent stabilizers for p53 Y220C using structure-based drug discovery methods 期刊论文  OAI收割
MOLECULAR DIVERSITY, 2025, 页码: 14
作者:  
Wen, Yiming;  Xu, Peijia;  Chen, Yijie;  Meng, Jingyi;  Zheng, Mingyue
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Transcriptomic Landscape Analysis Reveals a Persistent DNA Damage Response in Metabolic Dysfunction-associated Steatohepatitis Post-dietary Intervention 期刊论文  OAI收割
JOURNAL OF CLINICAL AND TRANSLATIONAL HEPATOLOGY, 2024, 页码: 15
作者:  
Zou, Zi-Yuan;  Ren, Tian-Yi;  Jiao, Ting-Ying;  Wang, Meng-Yu;  Huang, Lei-Jie
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An overview of PROTACs targeting MDM2 as a novel approach for cancer therapy 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 272, 页码: 8
作者:  
Li, Huiwen;  Cai, Xinhui;  Yang, Xiaoyu;  Zhang, Xuan
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Synthesis and biological evaluation of 4-imidazolidinone-containing compounds as potent inhibitors of the MDM2/p53 interaction 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 270, 页码: 16
作者:  
Lin, Zhitong;  Liu, Chen;  Yan, Ziqin;  Cheng, Jing;  Wang, Xiancheng
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LIM domain-containing protein Ajuba inhibits chemotherapy-induced apoptosis by negatively regulating p53 stability in colorectal cancer cells 期刊论文  OAI收割
MOLECULAR ONCOLOGY, 2023, 卷号: 17, 期号: 8, 页码: 1678-1691
作者:  
Xu, Beihui;  Li, Qi;  Zhang, Jianjun;  Chen, Fuxiang
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