机构

• 上海药物研究所 [11]
• 合肥物质科学研究院 [4]
• 近代物理研究所 [2]
• 海洋研究所 [1]

采集方式

• OAI收割 [18]

内容类型

• 期刊论文 [17]
• 学位论文 [1]

发表日期

• 2024 [1]
• 2023 [1]
• 2022 [4]
• 2020 [2]
• 2019 [3]
• 2018 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共18条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Quinazoline-2,4(1 H,3 H)-dione Scaffold for development of a novel PARP-targeting PET probe for tumor imaging 期刊论文  OAI收割 EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2024, 页码: 14 作者:  He, Chunfeng;  Shi, Hui;  Tan, Boyu;  Jiang, Zhaoning;  Cao, Rui   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/08/22 PARP  Oncology  Quinazoline-2,4(1H,3H)-dione  PET/CT   Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 19 作者:  Wang, Pingyuan;  Zhu, Wen-Ting;  Wang, Yajing;  Song, Shan-Shan;  Xi, Yong   |  收藏  |  浏览/下载：71/0  |  提交时间：2023/10/17 PARP1 inhibitor  Synthetic lethality  Drug resistance  Anticancer  Structure -activity relationship   Darinaparsin (ZIO-101) enhances the sensitivity of small-cell lung cancer to PARP inhibitors 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022 作者:  Cao, Guo-Zhen;  Ma, Li-Ying;  Zhang, Zong-Hui;  Wang, Xiao-Lin;  Hua, Jing-Han   |  收藏  |  浏览/下载：49/0  |  提交时间：2022/12/22 small-cell lung cancer  H3  3  PARP1  PARP inhibitor  darinaparsin  combination treatment   Design, synthesis and pharmacological evaluation of new PARP1 inhibitors by merging pharmacophores of olaparib and the natural product alantolactone 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 240, 页码: 114574 作者:  Kayumov, Muzaffar;  Jia, Li;  Pardaev, Azizbek;  Song, Shan-Shan;  Mirzaakhmedov, Sharafitdin   |  收藏  |  浏览/下载：35/0  |  提交时间：2024/03/21 PARP1  Olaparib  Alantolactone  Syntheticlethality  BRCA1/2mutant   Vanguard is a Glucose Deprivation-Responsive Long Non-Coding RNA Essential for Chromatin Remodeling-Reliant DNA Repair 期刊论文  OAI收割 ADVANCED SCIENCE, 2022 作者:  Zhang, Ben;  Thorne, Rick Francis;  Zhang, Pengfei;  Wu, Mian;  Liu, Lianxin   |  收藏  |  浏览/下载：35/0  |  提交时间：2022/12/23 genomic stability  HMGB1  long non-coding RNAs  PARP inhibitors  Vanguard   Repeated treatments of Capan-1 cells with PARP1 and Chk1 inhibitors promote drug resistance, migration and invasion 期刊论文  OAI收割 CANCER BIOLOGY & THERAPY, 2022, 页码: 14 作者:  Guo, Ne;  Li, Meng-Zhu;  Wang, Li-Min;  Chen, Hua-Dong;  Song, Shan-Shan   |  收藏  |  浏览/下载：38/0  |  提交时间：2022/06/15 Combination therapy  PARP1  resistance  CXCL3-ERK1/2 signaling  migration and invasion   The dual HDAC-PI3K inhibitor CUDC-907 displays single-agent activity and synergizes with PARP inhibitor olaparib in small cell lung cancer 期刊论文  OAI收割 JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2020, 卷号: 39 作者:  Ma, Liying;  Bian, Xing;  Lin, Wenchu   |  收藏  |  浏览/下载：43/0  |  提交时间：2020/11/30 SCLC  PI3K  HDAC  CUDC-907  PARP1  Olaparib  DSB repair  Combination treatment   The MYC Paralog-PARP1 Axis as a Potential TherapeuticTarget in MYC Paralog-Activated Small Cell Lung Cancer 期刊论文  OAI收割 FRONTIERS IN ONCOLOGY, 2020, 卷号: 10 作者:  Bian, Xing;  Wang, Xiaolin;  Zhang, Qiuyan;  Ma, Liying;  Cao, Guozhen   |  收藏  |  浏览/下载：40/0  |  提交时间：2020/11/30 small cell lung cancer  MYCparalog  PARP1  BET  DNA damage response   USP9X stabilizes BRCA1 and confers resistance to DNA-damaging agents in human cancer cells 期刊论文  OAI收割 CANCER MEDICINE, 2019, 卷号: 8, 期号: 15, 页码: 6730-6740 作者:  Lu, Qin;  Zhang, Fang-Lin;  Lu, Da-Yun;  Shao, Zhi-Ming;  Li, Da-Qiang   |  收藏  |  浏览/下载：37/0  |  提交时间：2020/07/01 BRCA1  breast cancer  deubiquitinase  PARP inhibitor  USP9X   Increased PARP1-DNA binding due to autoPARylation inhibition of PARP1 on DNA rather than PARP1-DNA trapping is correlated with PARP1 inhibitor's cytotoxicity 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF CANCER, 2019, 卷号: 145, 期号: 3, 页码: 714-727 作者:  Chen, Hua-Dong;  Chen, Chuan-Huizi;  Wang, Yu-Ting;  Guo, Ne;  Tian, Yu-Nan   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/03/21 PARP1 inhibitor  PARP1-DNA binding  PARP1-DNA trapping  poly(ADP-ribose) polymerase activity  cytotoxicity