机构

• 上海药物研究所 [9]
• 金属研究所 [3]
• 上海神经科学研究所 [3]
• 上海生物化学与细胞生... [3]
• 大连化学物理研究所 [2]
• 南海海洋研究所 [1]
• 更多

采集方式

• OAI收割 [23]

内容类型

• 期刊论文 [23]

发表日期

• 2018 [2]
• 2013 [1]
• 2011 [2]
• 2010 [3]
• 2009 [3]
• 2008 [2]
• 更多

学科主题

• Neuroscien... [4]
• Biochemist... [2]
• Biochemist... [1]
• Biotechnol... [1]
• Cell Biolo... [1]
• Chemistry,... [1]
• 更多

筛选

浏览/检索结果: 共23条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Synthesis, biological evaluation and structure-activity relationship of a novel class of PI3K alpha H1047R mutant inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 707-719 作者:  Zhang, Ning;  Yu, Zhimei;  Yang, Xiaohong;  Zhou, Yan;  Wang, Jia   |  收藏  |  浏览/下载：94/0  |  提交时间：2019/01/08 Anticancer drug  Phosphatidylinositol 3-kinase  Structure-activity relationship   Difuran-substituted quinoxalines as a novel class of PI3K alpha H1047R mutant inhibitors: Synthesis, biological evaluation and structure activity relationship 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 37-49 作者:  Zhang, Ning;  Yu, Zhimei;  Yang, Xiaohong;  Zhou, Yan;  Tang, Qing   |  收藏  |  浏览/下载：37/0  |  提交时间：2019/01/08 Proliferation  Anticancer drug  Phosphatidylinositol 3-kinase inhibitor  Apoptosis  Structure-activity relationship   Functional characterization of KlippelTrenaunay syndrome gene AGGF1 identifies a novel angiogenic signaling pathway for specification of vein differentiation and angiogenesis during embryogenesis 期刊论文  OAI收割 HUMAN MOLECULAR GENETICS, 2013, 卷号: 22, 期号: 5, 页码: 963-976 作者:  Chen, Di;  Li, Lei;  Tu, Xin;  Yin, Zhan;  Wang, Qing 收藏  |  浏览/下载：26/0  |  提交时间：2013/10/31 KLIPPEL-TRENAUNAY-SYNDROME  CORONARY-ARTERY-DISEASE  LYMPHATIC ENDOTHELIAL-CELLS  PHOSPHATIDYLINOSITOL 3-KINASE  MOLECULAR CHARACTERIZATION  KINASE PATHWAYS  TRANSGENIC MICE  SMOOTH-MUSCLE  ZEBRAFISH  EXPRESSION   Chitosan oligosaccharides inhibit LPS-induced over-expression of IL-6 and TNF-alpha in RAW264.7 macrophage cells through blockade of mitogen-activated protein kinase (MAPK) and PI3K/Akt signaling pathways 期刊论文  OAI收割 carbohydrate polymers, 2011, 卷号: 84, 期号: 4, 页码: 1391-1398 作者:  Ma, Pan;  Liu, Hong-Tao;  Wei, Peng;  Xu, Qing-Song;  Bai, Xue-Fang 收藏  |  浏览/下载：20/0  |  提交时间：2015/11/12 Chitosan oligomers  Inflammation  Mitogen-activated protein kinase  Phosphatidylinositol 3-kinase  Macrophage cells   Chitosan oligosaccharides suppress LPS-induced IL-8 expression in human umbilical vein endothelial cells through blockade of p38 and Akt protein kinases 期刊论文  OAI收割 acta pharmacologica sinica, 2011, 卷号: 32, 期号: 4, 页码: 478-486 作者:  Liu, Hong-tao;  Huang, Pei;  Ma, Pan;  Liu, Qi-shun;  Yu, Chao 收藏  |  浏览/下载：27/0  |  提交时间：2012/07/09 anti-inflammatory agents  arteriosclerosis  lipopolysaccharides  endothelial cells  chemokine  MAPK  phosphatidylinositol 3-kinase  interleukin-8  NF-kappa B  chitosan oligosaccharides   Up-regulation of PIK3CA promotes metastasis in gastric carcinoma 期刊论文  OAI收割 WORLD JOURNAL OF GASTROENTEROLOGY, 2010, 卷号: 16, 期号: 39, 页码: 4986-4991 Liu, JF; Zhou, XK; Chen, JH; Yi, G; Chen, HG; Ba, MC; Lin, SQ; Qi, YC 收藏  |  浏览/下载：54/0  |  提交时间：2011/07/03 PIK3CA  Phosphatidylinositol 3-kinase/Akt pathway  Metastasis  Gastric cancer  Akt   Inhibition of autophagy induced by overexpression of mda-7/interleukin-24 strongly augments the antileukemia activity in vitro and in vivo 期刊论文  OAI收割 CANCER GENE THERAPY, 2010, 卷号: 17, 期号: 2, 页码: 109-119 作者:  Yang, C;  Tong, Y;  Ni, W;  Liu, J;  Xu, W 收藏  |  浏览/下载：25/0  |  提交时间：2015/07/22 mda-7  interleukin-24  autophagy  Beclin-1  replication-competent adenovirus  phosphatidylinositol 3-kinase inhibitor   Adenosine triphosphate-sensitive potassium channel opener protects PC12 cells against hypoxia-induced apoptosis through PI3K/Akt and Bcl-2 signaling pathways 期刊论文  OAI收割 NEURAL REGENERATION RESEARCH, 2010, 卷号: 5, 期号: 22, 页码: 1706-1711 作者:  Zhang Hong;  Jia Chunhong;  Zhao Danyang;  Lu Yang;  Wang Runling   |  收藏  |  浏览/下载：14/0  |  提交时间：2021/02/02 BRAIN  ISCHEMIA  AKT  NEUROPROTECTION  EXPRESSION  SURVIVAL  DEATH  ATP-sensitive potassium channel  PC12 cells  hypoxia  apoptosis  pinacidil  phosphatidylinositol-3 kinase/v-akt murine thymoma viral oncogene homolog  Bcl-2   Neuregulin-1 enhances differentiation of cardiomyocytes from embryonic stem cells 期刊论文  OAI收割 MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING, 2009, 卷号: 47, 期号: 1, 页码: 41-48 作者:  Wang, Z;  Xu, GT;  Wu, YL;  Guan, Y;  Cui, L 收藏  |  浏览/下载：17/0  |  提交时间：2015/07/22 Neuregulin-1  Embryonic stem cells  Cardiomyocytes  Phosphatidylinositol 3-kinase   Alisol B acetate induces apoptosis of SGC7901 cells via mitochondrial and phosphatidylinositol 3-kinases/Akt signaling pathways 期刊论文  OAI收割 WORLD JOURNAL OF GASTROENTEROLOGY, 2009, 卷号: 15, 期号: 23, 页码: 2870-2877 作者:  Xu YongHong;  Zhao LiJie;  Li Yan   |  收藏  |  浏览/下载：63/0  |  提交时间：2021/02/02 RHIZOMA DRIED RHIZOME  PROTEIN-KINASE-B  PROSTATE-CANCER  ALISMATIS-RHIZOMA  BCL-2 FAMILY  TERPENE COMPONENTS  METHANOL EXTRACT  AKT  ORIENTALE  SURVIVAL  Alisol B acetate  Apoptosis  Mitochondria  Phosphatidylinositol 3-kinases/Akt  SGC7901 cells