中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共13条,第1-10条 帮助

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Targeting epigenetic machinery: Emerging novel allosteric inhibitors 期刊论文  OAI收割
PHARMACOLOGY & THERAPEUTICS, 2019, 卷号: 204, 页码: 24
作者:  
Ye, Fei;  Huang, Jing;  Wang, Hongbo;  Luo, Cheng;  Zhao, Kehao
  |  收藏  |  浏览/下载:33/0  |  提交时间:2020/07/01
AZD9291 inactivates the PRC2 complex to mediate tumor growth inhibition 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1587-1595
作者:  
Zhang, Kai-li;  Shen, Qian-qian;  Fang, Yan-fen;  Sun, Yi-ming;  Ding, Jian
  |  收藏  |  浏览/下载:56/0  |  提交时间:2020/07/01
C10ORF12 modulates PRC2 histone methyltransferase activity and H3K27me3 levels 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 11, 页码: 1457-1465
作者:  
Shi, Yi;  Ma, Hong-lei;  Zhuang, You-wen;  Wang, Xiao-xi;  Jiang, Yi
  |  收藏  |  浏览/下载:33/0  |  提交时间:2020/07/01
c10orf12modulatesprc2histonemethyltransferaseactivityandh3k27me3levels 期刊论文  OAI收割
actapharmacologicasinica, 2019, 卷号: 40, 期号: 11, 页码: 1457
作者:  
Shi Yi;  Ma Honglei;  Zhuang Youwen;  Wang Xiaoxi;  Jiang Yi
  |  收藏  |  浏览/下载:16/0  |  提交时间:2020/07/01
Development of a high-throughput fluorescence polarization assay for the discovery of EZH2-EED interaction inhibitors 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 2, 页码: 302-310
作者:  
Zhu, Mao-rong;  Du, Dao-hai;  Hu, Jun-chi;  Li, Lian-chun;  Liu, Jing-qiu
  |  收藏  |  浏览/下载:42/0  |  提交时间:2019/01/08
developmentofahighthroughputfluorescencepolarizationassayforthediscoveryofezh2eedinteractioninhibitors 期刊论文  OAI收割
actapharmacologicasinica, 2018, 卷号: 39, 期号: 2, 页码: 302
作者:  
Zhu Maorong;  Du Daohai;  Hu Junchi;  Li Lianchun;  Liu Jingqiu
  |  收藏  |  浏览/下载:23/0  |  提交时间:2020/07/01
Structure of the PRC2 complex and application to drug discovery 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 963-976
作者:  
Shi, Yi;  Wang, Xiao-xi;  Zhuang, You-wen;  Jiang, Yi;  Melcher, Karsten
  |  收藏  |  浏览/下载:28/0  |  提交时间:2019/01/08
structureoftheprc2complexandapplicationtodrugdiscovery 期刊论文  OAI收割
actapharmacologicasinica, 2017, 卷号: 38, 期号: 7, 页码: 963
作者:  
Shi Yi;  Wang Xiaoxi;  Zhuang Youwen
  |  收藏  |  浏览/下载:17/0  |  提交时间:2020/07/01
BASIC PENTACYSTEINE Proteins Repress ABSCISIC ACID INSENSITIVE4 Expression via Direct Recruitment of the Polycomb-Repressive Complex 2 in Arabidopsis Root Development 期刊论文  OAI收割
PLANT AND CELL PHYSIOLOGY, 2017, 卷号: 58, 期号: 3, 页码: 607-621
作者:  
Mu, Ying;  Zou, Meijuan;  Sun, Xuwu;  He, Baoye;  Xu, Xiumei
  |  收藏  |  浏览/下载:22/0  |  提交时间:2022/03/28
Identification of novel ezh2 inhibitors through pharmacophore-based virtual screening and biological assays 期刊论文  iSwitch采集
Bioorganic & medicinal chemistry letters, 2016, 卷号: 26, 期号: 15, 页码: 3813-3817
作者:  
Wu, Yunlong;  Hu, Junchi;  Ding, Hong;  Chen, Limin;  Zhang, Yuanyuan
收藏  |  浏览/下载:43/0  |  提交时间:2019/05/09