中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [10]
昆明植物研究所 [2]
采集方式
OAI收割 [12]
内容类型
期刊论文 [12]
发表日期
2021 [1]
2016 [1]
2015 [1]
2012 [3]
2011 [1]
2008 [1]
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学科主题
Pharmacolo... [1]
Toxicology [1]
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Discovery of pseudolaric acid A as a new Hsp90 inhibitor uncovers its potential anticancer mechanism
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 104963
作者:
Liu,Jiangxin
;
Wu,Xing-De
;
Li,Wenyan
;
Yuan,Zaifeng
;
Yang,Kun
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/04/02
Pseudolaric acid A
Hsp90 inhibitor
Apoptosis
NMR
Structure-activity relationship
Photoaffinity-based probe
Protein-ligand interaction
MOLECULAR CHAPERONE
PROTEIN
TARGET
CANCER
KINASE
NMR
IDENTIFICATION
SELECTIVITY
BINDING
DESIGN
Modified Release and Improved Stability of Unstable BCS II Drug by Using Cyclodextrin Complex as Carrier To Remotely Load Drug into Niosomes
期刊论文
OAI收割
MOLECULAR PHARMACEUTICS, 2016, 卷号: 13, 期号: 1, 页码: 113-124
作者:
Chi, Liandi
;
Wu, Delin
;
Li, Zhuo
;
Zhang, Minmin
;
Liu, Hongchun
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/01/08
niosomes
pseudolaric acid B
remote loading
pH gradient
retarded release
enzymatic stability
Dramatic improvement of the solubility of pseudolaric acid B by cyclodextrin complexation: Preparation, characterization and validation
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2015, 卷号: 479, 期号: 2, 页码: 349-356
作者:
Chi, Liandi
;
Liu, Ruihao
;
Guo, Tao
;
Wang, Manli
;
Liao, Zuhua
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
Cyclodextrins (CDs)
Pseudolaric acid B (PAB)
Solubilization
Molecular simulation
Validation
Newly discovered angiogenesis inhibitors and their mechanisms of action
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2012, 卷号: 33, 期号: 9, 页码: 1103-1111
作者:
Miao, Ze-hong
;
Feng, Jian-ming
;
Ding, Jian
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
cancer therapy
angiogenesis inhibitor
antiangiogenic mechanism
hypoxia-inducible factor 1 alpha
pseudolaric acid B
AL3810
Pseudolaric acid B-driven phosphorylation of c-Jun impairs its role in stabilizing HIF-1alpha: a novel function-converter model
期刊论文
OAI收割
JOURNAL OF MOLECULAR MEDICINE-JMM, 2012, 卷号: 90, 期号: 8, 页码: 971-981
作者:
Yu, Bing
;
Li, Mei-Hong
;
Wang, Wei
;
Wang, Ying-Qing
;
Jiang, Yi
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
c-Jun
Hypoxia inducible factor 1 alpha
JNK
Pseudolaric acid B
Ser63/73 phosphorylation
Pseudolaric acid B induces apoptosis via proteasome-mediated Bcl-2 degradation in hormone-refractory prostate cancer DU145 cells
期刊论文
OAI收割
TOXICOLOGY IN VITRO, 2012, 卷号: 26, 期号: 4, 页码: 595-602
作者:
Zhao, Dandan
;
Lin, Feng
;
Wu, Xingde
;
Zhao, Qinshi
;
Zhao, Binjiahui
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2012/06/07
Pseudolaric acid B
Hormone-refractory prostate cancer
Apoptosis
Bcl-2 degradation
Proteasome
Reactive oxygen species
Biotransformation of pseudolaric acid B by Chaetomium globosum
期刊论文
OAI收割
PROCESS BIOCHEMISTRY, 2011, 卷号: 46, 期号: 10, 页码: 2064-2067
作者:
Zhang, Xing
;
Ye, Min
;
Gong, Yu-jing
;
Feng, Lin-Min
;
Tao, Si-Jia
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
Biotransformation
Chaetomium globosum
Pseudolaric acid B
Antifungal activity
Candida albicans
Construction of the core of pseudolaric acid A and mechanistic studies on intramolecular [4+3] cycloaddition
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2001, 卷号: 12, 期号: 2, 页码: 113-116
作者:
Jiang, XT
;
Ou, LG
;
Han, DM
;
Zhai, YF
;
Bai, DL
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
pseudolaric acid A
5, 7-membered fused ring
hemiacetal
intramolecular [4+3] cycloaddition
mechanism
Studies on the total synthesis of Pseudolaric acid A stereocontrolled synthesis of the seven-membered lactone
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 1999, 卷号: 10, 期号: 4, 页码: 281-284
作者:
Hu, YH
;
Ou, LG
;
Wang, XL
;
Bai, DL
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Pseudolaric acid A
stereocontrol synthesis
seven-membered lactone